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Both sympathetic and parasympathetics are part of the __ nervous system and have how many neurons in their pathway?
part of the autonomic nervous system, have 2 neurons in their pathway (one preganglionic, one postganglionic)
What are splanchnic nerves? What do they innervate? Do they have sensory or motor fibers?
Splanchnic nerves innervate the internal organs in the chest, abdomen, and pelvis. They have both sensory and motor fibers.
Only this type of splanchnic nerves carry parasympathetic (rest and digest) fibers
Pelvic splanchnic nerves
What are the differences in the two types of cholinergenic receptors? What neurotransmitter binds here? Are they in the parasympathetic or sympathetic nervous system?
Nicotinic = always excitatory, muscarinic = can be excitatory or inhibitory
Acetylcholine binds here. Found in both parasympathetic and sympathetic nervous system.
What are the two different types of adrenergic receptors? What neurotransmitter binds here? Are these in the sympathetic or parasympathetic nervous system?
Alpha type = smooth muscle contraction, vasoconstriction
Beta type = cardiac stimulation, smooth muscle relaxation, vasodilation
Norepinephrine/epinephrine binds here
Found in postganglionic parts of the parasympathetic nervous system
What four cranial nerves have parasympathetic functions?
CN III - oculomotor
CN VII - facial
CN IX - glossopharyngeal
CN X - vagus
Where on the spinal cord do sympathetics originate vs. parasympathetics?
Sympathetics = thoracolumbar origins
Parasympathetics = craniosacral origins
Which part of the nervous system has LONG PREganglionics and SHORT POSTganglionics?
Parasympathetic
Which part of the nervous system has SHORT PREganglionics and LONG POSTganglionics?
Sympathetic
What is “tone?" Describe sympathetic tone vs. parasympathetic tone.
Both sympathetics and parasympathetics are always activated at a consistent level at rest.
sympathetic = blood vessels
parasympathetic = heart and smooth muscle of digestive and urinary tracts
What is referred pain? What is an example?
Referred pain: autonomic aspects of pain crossfire/synapse/integrate with somatics slightly
Ex: pain in gall bladder can manifest as pain in the shoulder
What is the difference between exteroreceptors, interoreceptors, and proprioceptors?
Exteroreceptors - stimuli arising outside the body
Interoreceptors - stimuli arising inside the body
Proprioceptors - stimuli in skeletal muscles, tendons, ligaments, joints, and connective tissue
What are the differences between A-delta type fibers and C type fibers?
A-delta = fast-adapting (stop firing fairly quickly even if stimulus is still being applied), myelinated
C = slow-adapting (continue to fire longer after persistent stimulus is applied), unmyelinated
What is a free nerve ending? What are the different classifications of these, aka NONENCAPSULATED fibers
free nerve ending is an unspecialized, unencapsulated sensory nerve terminal that detects pain, temperature, mechanical pressure, and touch.
General - detect crude touch and pain
Merkel discs - light touch and texture, slow adapting
Hair root plexuses - light touch and movement on hair, fast adapting
What do Meissner’s (encapsulated) corpuscles do?
Rapid-adapting, detects light touch and low frequency vibrations
What do lamellar/Pacinian (encapsulated) corpuscles do?
Rapidly adapting, detects deep stretch, pressure, high frequency vibrations
What do Ruffini (encapsulated) corpuscles do?
Slow adapting, deep within skin, joint capsules, and ligaments
What do muscle spindles vs. golgi tendon organs do?
muscle spindle - in muscle, senses stretch and the speed of stretch
golgi tendon organ - in tendon, senses tension
Explain the muscle stretch reflex and the two efferent signals it sends
The muscle spindle senses stretch and sends an afferent signal to the spinal cord.
efferent - excitatory to contract quad
efferent - inhibitory to prevent antagonist contraction
Describe the tendon reflex and its two interneurons.
Tendon organs sense contraction, then send afferent signal to spinal cord
Interneuron - excitatory to antagonist
Interneuron - inhibitory to agonist
What five nerves innervate the eye?
Optic, oculomotor, trochlear, opthalmic (first branch of trigeminal), abducens
The three components of the surface anatomy of the eye are the palpebral fissure, iris, and conjunctiva. What do they each do?
Palpebral fissure - space between upper and lower eyelids
iris - colored portion around pupil
conjunctiva - thin clear mucus membrane covering front portion of eye
What does the lacrimal gland do?
Lubricates eye surface with lacrimal fluid aka tears. Moves down and across eye inwards towards nasolacrimal duct
What is the posterior cavity of the eye?
Everything behind the lens/ciliary body
What is the anterior cavity? It has two parts, what are these?
Anterior cavity - in front of ciliary body and lens
anterior chamber - in front of iris
posterior chamber - behind iris
What are the two fibrous parts of the eye? What do they do?
Cornea and sclera are continuous with each other. Sclera = white part of eye, cornea = clear and covers iris/pupil/lens
What structures are located deep to the fibrous part of the eye?
choroid, ciliary body, iris
What are the two muscles in the iris and what do they do?
Sphincter pupillae - size decreases, parasympathetic
Dilator pupillae - size increases, sympathetic
What does the ciliary body produce?
Aqueous humor for anterior segment.
What is the process of parasympathetic control of the eye?
via OCULOMOTOR nerve
parasympathetics of oculomotor nerve exit edinger westphall nucleus, travel to ciliary ganglion and synapse, go to sphincter pupillae
What is the process of sympathetic control of the eye?
fibers work their way up from thoracolumbar region, redistribute themselves around carotid and become carotid plexus, exit, then go to dilator pupillae
The retina is essentially an extension of ___.
The optic nerve
What is the optic disc?
“blind spot,” where all nerve fibers bundle together and form optic nerve
What is the macula?
Light is focused here for fine detailed vision
What are the six extraocular muscles that control eye movement? What nerves are they controlled by?
Lateral and medial rectus, superior and inferior rectus, superior and inferior oblique
All controlled by oculomotor except for lateral rectus (abducens) and superior oblique (trochlear)
What does the lens do?
Focuses light on specific areas of retina for detail vision
What is the difference between myopic and hyperopic eyes?
myopic - eye is too long, nearsighted (can only see close)
hyperopic - eye is too short, farsighted (can only see far)
What do rods and cones do?
convert light into electrical and chemical signals to the brain. embedded in pigment cells
What are the two main visual pigments in rods and cones? What is the cyclic process that occurs here?
Rhodopsin and opsin.
Starts as rhodopsin in the dark. (opsin + 11-cis-retinal)
light hits it, turns it into opsin + 11-trans-retinal, then components separate
Enzymes convert it back into 11-cis-retinal and it recombines with opsin to once again form opsin
What happens when these changes occur in retinal?
A G-protein pathway is activated and a signal is sent
Vision is a three-neuron pathway. What are the three parts of this pathway?
Photoreceptor
Bipolar neuron
Ganglion cell
What are the differences between rods and cones?
RODS- noncolor vision, high sensitivity (low light), more
CONES - color vision, low sensitivity (bright light), less
What is the nasal vs. temporal retina?
nasal - inner half, detects outer visual field
temporal - outer half, detects inner visual field
Describe the steps of vision processing
Light detected by cones
Signal passed to bipolar neuron
Signal passed to ganglion cell
Axons of ganglion cell come together to form optic nerve
Optic nerve travels back and forms optic chiasm, where fibers from nasal retina cross
Nerve fibers travel down the optic tract. Will have fibers from nasal retina of contralateral side and fibers from temporal retina of ipsilateral side.
How is smell detected?
Odorants dissolve into nasal epithelium
They bind to receptors on olfactory neurons (which are bipolar)
Olfactory neurons form olfactory bulb, then travel through nasal cavity to synapse in olfactory tract
What are the receptor cells for taste?
Gustatory epithelial cells
What three nerves innervate the tongue?
Anterior 2/3 - facial
epiglottis - vagus
posterior 1/3 - glossopharyngeal
What are the function of the ossicles and tympanic membrane in the middle ear?
Tympanic membrane recieves sound and rattles ossicles, which communicates sound to inner ear
What are the three ossicle bones?
malleus, incus, stapes
What is the function of the pharyngotympanic tube?
Communication between the pharynx and middle ear, helps regulate pressure from external environment
The inner ear is innervated by one nerve and has two main parts. What are these?
The vestibular system (balance) and cochlea (hearing). innervated by vestibulocochlear nerve, which splits into two
How do otolith organs (utricle, macula, saccule) function in the vestibular system?
These organs are flat, jelly-like slabs weighed down by calcium crystals (otoconia). when these crystals move, stereocilia in neurons detect these changes
How do semicircular canals function in the vestibular system?
They are filled with fluid; changes in acceleration of the fluid shifts cupula, which is detected as movement
Which cranial nerve innervates most of the visceral organs?
vagus