krebs cycle

where does the krebs cycle take place

• matrix of the mitochondria

what does the Krebs cycle involve

• coenzymes NAD, CoA, FAD

how many stages of krebs are there

6 stages

stage 1

• CoA and acetate detach

• CoA can now be reused

• Acetate (2C) joins with oxaloacetate (4C) to make CITRATE (6C)

stage 2 of the krebs cycle

• Citrate is decarboxylated and dehydrogenated to form a 5C compound

• ( a co2 molecule is released)

• The pair of hydrogen atoms are accepted by NAD to become reduced NAD

stage 3

• the 5C compound is decarboxylated and dehydrogenated to from a 4C compound

• co2 is released

• the pair of hydrogen atoms are accepted by NAD to become reduced NAD

stage 4

• the 4C compound is changed into another 4C compound using CoA enzyme.

• this enzyme is reused in this part of the cycle again and again

• a molecule of ATP is produced through substrate level phosphorylation of ATP

stage 5

• the second 4C compound is converted into a third 4C compound

• the pair of hydrogen atoms are accepted by FAD to become reduced FAD

stage 6

• the third 4C compound is then dehydrogenated back into oxaloacetate 4C

• the pair of hydrogen atoms are accepted by NAD to become reduced NAD

krebs cycle diagram

products of krebs per cycle

• 3 reduced NAD

• 1 reduced FAD

• 2 co2

• 1 ATP

products of krebs per molecule of glucose

• 6 redcued NAD

• 2 reduced FAD

• 4 Co2

• 2 ATP

why can krebs cycle repeat

• the acceptor molecule oxaloacetate is regenerated throughout the reaction so it can start all over again by adding another acetyl CoA