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Biochemistry of the Eye, Lecture 5
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Retinoic acid
Carboxylic acid functional group
Used for the synthesis of glycoproteins
Retinal
Aldehyde functional group
Used for vision
Retinol
Alcohol functional group
Used for transport and hormones
Retinyl Ester
Attached to a fatty acid
Used for storage
Retinol Binding Protein (RBP) and Prealbumin (PA)
Carry retinol between the liver and the retina
Cellular Retinol Binding Protein (CRBP)
Carries retinol in the RPE and Müller cells
Cellular Retinoic Acid Binding Protein (CRABP)
Carries retinoic acid in amacrine and Müller cells
Cellular Retinaldehyde Binding Protein
Carries 11-cis-retinal in RPE and Müller cells
Interphotoreceptor Retinoid Binding Protein
Carries 11-cis-retinal and retinol in the interphotoreceptor matrix