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What is observational research?
nonexperimental research
What is unique of observational research?
researchers do not intervene
What are correlational designs?
examine relationships between variable
What is used in observational research?
correlational designs
What may observational research be used to address?
disease/burden prevalence, prognosis, etiology
What are the three major observational research designs?
case-control, cohort, cross-sectional/descriptive
What is a case-control design?
researchers investigate factors associated with a disease or outcome
When is a case-control design done?
when the outcome of interest is rare
What do researchers study in a case-control design?
group of individuals with or without the disease of interest and look back in time to see whether a historical exposure is more common among the cases or controls
Can case-control studies support temporality (i.e., passage of time)?
depends
What is a cohort study?
used to evaluate factors associated with a disease or determining the prognosis of a disease
How is a cohort study performed?
a group of individuals exposed and not exposed to a variable and followed over time to compare the impact of a particular exposure on different outcomes
Can cohort studies support temporality?
yes
What are descriptive studies?
researchers describe or quantify a certain attribute/phenomena
What is descriptive correlational?
researchers investigate relationships between attributes/phenomena
Can cross-sectional descriptive studies support temporality?
no
What are advantages of observational studies?
can collect large amount of data in a small amount of time, can identify relationships between variables, can support temprality
What studies can support temprality?
cohort and case control
What are limitations of observational studies?
provides weak evidence for causal interference; subject to bias
What studies are subject to bias?
case control and cohort
What differs among observational study designs?
timing of data collection
What can case-control and cohort studies provide?
evidence of temporality and weak evidence to support causality
What is selection bias?
was the cohort representative of a defined population? was everyone included who should have been?
What is measurement bias?
was the exposure and outcome measured using valid and reliable instruments? were participants studied long enough to detect study outcomes?
What is confounding?
were extraneous variables controlled through the research design or statistical procedures?
The follwoingn is characteristic of observational research?
researchers observe phenomena as they naturally occur
In this type of study design, a group of individuals exposed and not exposed to a variable are followed prospectively over time to compare the impact of a particular exposure o different outcomes?
cohort study
What is a population?
the aggregate of cases in which a researcher is interested
What is accessible population?
the aggregate of cases that conform to designated criteria and that are accessible for a study
What is a target population?
the aggregate of cases about which the researcher would like to generalize
What is egibility criteria/inclsuive criteria?
criteria that specify population characteristics
What are kinds of eligibility criteria?
cost, practical constraints, people’s ability to participate, design considerations
What is sampling?
selection of a portion of the population to represent the entire population
What are elements?
basic population unit about which information is collected
What is a sample?
a subset of population elements
What is a nonprobability sample?
nonrandom methods
What is a probability sample?
random selection
What is convenience sampling?
using the most conveniently available people as participants
What are examples of convenience campling?
snowball and respondent-driven
What is snowball sampling?
network sampling/chain sampling
What is quota sampling?
selecting participants to ensure that diverse segments are represented in the sample according to predetermined population characterisitics
What is consecutive sampling?
recruiting all the people from an accessible population who meet the elibility criteria over a specific time interval or for a specified sample size
What is purposive sampling?
purposely selecting people who are consdiered particularly knowledgeable about the issue under study
What is simple random sampling?
using a sampling frame (a complete list of all elements in the population), particopants are chosen randomly
What is stratified random sampling?
dividing the population into two or more homogenous strata and randomly selecting participants from each stratum
What is multistage cluster sampling?
when a complete list of all elemets is unavailable, broad groups (clusters) are selected first, followed by random sampling within the chosen clusters
What is systematic sampling?
selecting every 4th case from a list (e.g., every 10th person on a patient roster)
What is part of nonproabability sampling?
convenience, quota, consectuive, purposive
What is probability sampling?
simple random, stratified random, multistage cluster, systematic
What factors affect sample size?
effect, homogeniety of the population, cooperation and attrition, subgroup analyses
What is effect size?
refers to the strength of relationships among research variables. When the relationship between the independent and depedent variables is strong, a relatively small sample size may be adequate to detect the relationship statistically
What is homogeneity of the population?
if the population is realtively homogenous, a small sample may be adequate to provide reliable results
What is cooperation and attrition?
the level of participant cooperation and the anticipated rate of attrition can affect sample size requirements
What is subgroup analyses?
when the sample is divided into subgroups to examine differences or subgroup effects, the sample must be large enoguh to support analyses
What is the first step in sampling?
identify the population
What is the second step in sampling?
specify the eligibility criteria
What is the third step in sampling?
specify the sampling plan
What is the fourth step in sampling?
recruit the sample
A nurse researcher identified their accessible population as women with high-risk pregnancies in the state of New York. Which group might be the researcher’s target population?
all women with high-risk pregnancies in the united states
A nurse researcher recruits study participants by placing a recruitment poster at the entrance to a reproductive healthcare center. What type of sampling did the researcher use?
convenience sampling
A researcher extracts information about hosptial readmissions from a population of 6,000 client records. The researcher samples every 20th record from the population, beginning with record number 5. What type of sampling did the researcher use?
systematic sampling
What are selecting types of measures?
self-reports, observations, biomarkers, records
What are considerations for selecting instruments?
resources, population appropriateness, norms and comparisons, clinical significance, administration issues, reputation
What is pretesting the data colleciton package?
identify parts hard to read or understand, identify questions found objectionable or offensive, assess if sequencing is sensible, evaluate training needs of data collectors, do measures yield data with sufficient variability
What are specific types of closed-ended questions?
dichotomous, multiple-choice, rank-order, forced-choice, rating scale, checklists, visual analog scales
What are likert-tupe summated rating scales?
agree vs, disagree, positive vs. negative statements
What are cogitive and neurophysiological tests?
intelligence tests, mini-mental status examination (MMSE)
What is administering structured self-report instrumetns?
collecting interview data, collecting questionnaire data through in-person distribution, collectiong questionnaire data through the mail, collection questionnaire data via the internet, follow-up reminders, patient-reported outcomes measurement information system
What is a response bias?
a systematic tendency for respondents to give biased answers i reaction to the interviewer’s beahavior, appearance, or manner of questioning
What is a social desirability response bias?
the tendency of some individuals to provide answers that they believe are socially acceptable or favorable
What are exxtreme responses?
a bias to consistently select the most extreme reponse options
What are yea-sayers/acquiescence response set?
a tendency to agree with statements regardless of their content
What are nay-sayers?
a tendency to disagree with statements regardless of their content
What is structured observation?
recording behaviors, interactions, and events in a systematic way
What is time-sampling?
the time frames may be selected systematically or at random
What is event sampling?
using integral behaviroal sets or events for observation
What are technical aids in observations?
auditory, video, mobile apps
What is evaluation of structured observation?
assimilatory biases, halo effect, error of leniency, error of severity
What are advantages of questionnaires?
cost, anonymity, interviewer bias
What are advantages of interviews?
response rates, audience, clarity, depth of questioning, missing information, supplementary data
What are biomarkers?
a characteristic that is objectively measured and evaluated as an indicator of normal biolgoical processes, pathogenic processes, or pharmacological response toa therapeutic intervention
What are types of biomarkers?
routine clinical measurements, laboratory tests of blood, other blood fluids, and tissue samples
What are advantages of biomarkers?
objective measures of biological processes, more accurate and precise than self-report or psychological measures, provide valid indicators of target variables
What are disadvantages of biomarkers?
often expensive to collect and analyze, procedures may infleunce the variables being studies, variability across laboratory protocols can affect results, normative values may be biased or not generalizable across populations
What are physical performance tests?
measure clients’ abilities and skills; various tests to measure balance, mobility, endurance, and flexibility
What is selecting research personnel?
experience, congruence with sample characteristics, unremarkable appearance, personality
What are training data collectors?
demosntrations, mock interviews
Which statement about interviews and questionaires is true?
questionnaires are appropriate for broader audiences than interviews; response rates tend to be higher with interviews than with questionnaires
Which statement about biomarkers (biophysiologic measures) is true?
oxygen saturation is an example of a measurement