⭐️Vet Path Exam #6 Quiz

Sclera

The uvea is composed of all components (iris, choroid, ciliary body) EXCEPT?

Ciliary body

Which ocular structure forms the iridocorneal angle which aids in the drainage of aqueous humor and is decreased in glaucoma?

Clear hydrogel composed of collagen, hyaluronic acid, and hyalocytes

What is the vitreous?

Synopthalmia

What is this lesion in a calf?

Charolais cattle

Which cattle breed is predisposed to the lesion in the optic nerve pictured here

Diffuse iris melanoma

A cat presents with the following lesion in the eye. What is the top differential?

Goniodysgenesis

In primary glaucoma, what condition results because of a defect in the structure and function of the iridocorneal angle affecting the pathway for aqueous humor drainage?

Retinal hypertrophy

All of the following (Collapse of the iridocorneal angle, sclereal thinning, atrophy of the ciliary processes and optic nerve head cupping) features are histologic lesions present in glaucoma EXCEPT?

Ectropion

What condition is present in this dog?

Inflammation secondary to leakage of meibomian gland secretions

Chalazion is defined as?

Habronema

Which nematode is responsible for the eosinophilic granulomas present in this equine eye?

Infection with Moraxella Bovis; transmission is via mechanical vectors

A cow presents with the following lesion. What is the cause and what do you tell the owner?

Descemetocele

A horse presents with the following lesion. What is the consequence if left untreated?

Uveodermatologic syndrome

A 4 year old, female spayed Siberian Husky is presented to you for a second opinion. The owner tells you that when the dog was young, she had mostly black fur with some white spots then as the dog aged the white fur started to become more prominent starting around the eyes and muzzle (top image). The husky is now mostly white like the image on the bottom. The owner also states that the dog is stumbling around the house more frequently. What is the top differential?

Hemidesmosomes

Basal layer keratinocytes function to attach the epidermis to the basement membrane, and thus the dermis, via which structure?

Melanocytes

Which cell is located in the basal layer of the epidermis and is responsible for giving skin and hair their color?

Dermis

Which layer of the skin provides structure, toughness, and flexibility to the skin?

Do not scrub the skin before biopsying

What basic principle do you need to follow when obtaining samples from the skin?

Plasmacytoma

A dog presents to you with an interdigital mass. The histology report describes it as a round cell tumor with abundant amyloid deposition. What is your diagnosis?

Comedone

Which term is given to a lesion that may or may not be raised and is a small dilated follicular opening and infundibulum that is plugged by follicular hyperkeratosis and sebum.

Lentigo simplex

Which lesion describes a hyperpigmented macule that is incidental and considered congenital?

Papule

You are presented with a dog that has a raised dermal lesion that is less than 1 cm in diameter. What term do you use to describe it?

3

Which hypersensitivity reaction is thought to contribute to many cases of vasculitis

Purpura hemorrhagica

A horse presents with limb edema (first image). After some time the owner notes that the horse has started to develop red to purple patches on the skin and mucous membranes that you recognize as macules (second and third image). What is the top differential?

Degradation of the adhesion between keratinocytes that results in separation and clefting

What disease type best describes acantholytic disease

Pemphigus vulgaris

A dog is presented to you for worsening skin lesions. The histology report describes deep vesicular lesions causing flaccid vesicles and bullae that progress to deep erosions and ulcers particularly in the oral mucosa and mucocutaneous junctions. On physical examination, the dog is febrile and depressed. What is the top differential?

Autoantibodies directed at self antigens within the basement membrane of the skin resulting in vesicles or Bullae

Bulbous dermatoses or subepidermal blistering disease, is caused by what?

Thymoma

A dog is necropsied and the below image is the pluck taken out. The star indicates the lesion. You also appreciate the esophagus to be slightly more dilated than normal. On the histology report, it is noted that the lesion is composed of multiple nodules of thymic epithelial cells with loss of distinction between normal thymic nodules and neoplastic nodules. What is the top differential?

Corynebacterium pseudotuberculosis

A goat presents with the following lesion (first image) and multiple other goats on the farm have similar lesions. The second image is the lesion on cut surface. Based on the history and gross lesion, what is the most likely etiology?

Porcine circovirus 2

You get called out to a pig farm and the farmer mentions that a large number of grower and finisher pigs particularly have been losing weight. You necropsy a clinically affected pig and appreciate a generalized lymphadenopathy. The histology report notes the lymph nodes are infiltrated with numerous macrophages and occasionally there are large botryoidal cytoplasmic inclusions. What is the diagnosis?

Mycobacterium bovis

This is the lymph node from a cow that was firm on palpation. Histologically the areas of caseous necrosis are composed of granulomatous inflammation and acid-fast coccobacilli. What is the top differential?

Lymphoid hyperplasia

You appreciate splenomegaly on abdominal ultrasound of a dog. On necropsy, the splenic parenchyma contains multifocal, white to tan, distinct nodules that are soft to firm on palpation. Based on this gross appearance of the spleen on cut surface, what is the top differential?

Petechiations and hemorrhage in the lymph nodes and kidneys; splenic infarcts

Which gross depiction fits best with the necropsy findings from classical swine fever

Shar pei

In which breed is canine langhans cell histiocytosis most common

Peribronchial

A 12 year old cat is diagnosed with feline pulmonary Langerhans cell histiocytosis. Histologically, which location do histiocytes (aka macrophages) preferentially occupy in this condition?

Bernese Mountain dog

Which breed is predisposed to histiocytic sarcoma?

Spleen and bone marrow

Hemophagocytic histocytic sarcoma primary affects which sites?

It can affect any age

Which is true regarding lymphoma

Biopsy with IHC

Which method of diagnosing lymphoma is the gold standard and considered the most diagnostic?

T cell rich large B cell Lymphoma

Which type of lymphoma is the most common in equids

Splenic

Which of the following is not a form of sporadic bovine lymphoma

Uterus, heart, spinal cord, and abomasum

A cow is necropsied, and you appreciate a generalized lymphadenopathy. On cut surface all of the lymph nodes are expanded by multifocal, white, soft, bulging masses like those in the image below. What other locations are the most common location in cows for this condition?

generalized lymphadenopathy

Which gross presentation of lymphoma is considered the most common in dogs?

Immunohistochemistry

Which method is the best for differentiating DLBCL (diffuse large B cell lymphoma) and PTCL-NOS (peripheral T cell lymphoma-not otherwise specified)?

Marginal zone lymphoma

Splenectomy is the treatment of choice for which type of nodal lymphoma especially if caught early?

Epitheliotropic T cell lymphoma occurring at mucocutaneous junctions

Which of the following descriptions best fits mycosis fungoides?

Leukemia

A hemolymphatic neoplasm that originates in the bone marrow is called?

Acute leukemia

Which neoplasm is composed of immature neoplastic lymphocytes originating from the bone marrow that has a poor prognosis (days)?

Trauma

Which of the following is the most common cause of auricular hematomas?

Young cats with bilaterally swollen and painful auricles

Which presentation is the most common in auricular chondritis?

Dermatophilus congolensis

A goat presents with multifocal dermal proliferations that are crusted and in some areas ulcerated. Histologically there are gram positive bacteria that form "rail road tracks." What is the diagnosis?

Cats

In which species are ceremonious adenocarcinomas the most common auricular neoplasms?

Pasteurella multocida

In pigs, which organism is considered the most common cause of otitis media?

Tympanokeratoma

An aural mass composed of keratin, granulomatous inflammation, and cholesterol crystals within a fibrovascular stroma is called?

Stratum corneum

Which epidermal layer is responsible for acting as a barrier to water loss?

Dermis

In which layer are a majority of the structures (adnexal, sebaceous and sweat glands) of the skin found?

Clinicians, dermatologists, and pathologists should work together

What is one of the most important things to consider related to dermatology issues in an animal?

Dermoid cyst

A Rhodesian ridgeback dog presents with a soft slightly fluid filled mass on dorsal midline. What is the top differential?

Inappropriate NSAID use

Epidermal/dermal atrophy can result from all of the following except?

Papilloma

Which term best fits the gross lesion seen here?

Epidermal hyperplasia

Which feature is a hallmark of cutaneous pox virus lesions?

Severe ulceration with secondary bacterial infection

All of the following (latent infection without skin lesions, Proliferative nonneoplastic lesions, and malignant transformation) are possible outcomes of papillomavirus except for?

Pyoderma

Collarettes are common lesions that develop in which condition?

Psoroptes

Which non-burrowing mite is responsible for crusting, slope in, and pruritic dermal lesions in large animals?

Cheyletiella

Which mite lives on the skin surface and causes hyperkeratosis like seen in this image

Phaeohyphomycosis

Which pigmented fungus can result in cutaneous nodules in cattle, cats, and horses?