Anti neoplastics: non specific

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Pharm exam 2

Last updated 7:44 PM on 10/11/26
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5 Terms

1
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Doxorubicin

Use: Cancer

Special considerations: Pulmonary and cardiac toxicity. urine my turn red 1-2 days after admin (Harmless). Cardioprotective durg (dexrazoxane may be given)

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Cardiac toxicity (Doxorubicin)

Weight gain ( 2 lb in 24 hrs or 3-5lb in a week)

Lung sounds (crackles)

Report: SOB, edema, fatigue

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Hormonal drugs

Used to block growth of cancer cells that are hormone specific Ex. breast and prostate cancer

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Tamoxifen (Hormonal drugs)

Competes with estrogen to treat breast cancer

  • Menopause symptoms (hot flashes, spotting, moodiness, vaginal dryness)

  • Hypercalcemia (monitor calcium and bone denstiy)


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Cisplatin (alkalining agent)

AE: Nephrotoxicity, neurotoxic, ototoxicity

NI: 2-3 liters of water daily, drug interactions with aminogylosids