PRX 340 Recalled Drugs

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14 Terms

1
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Terfenadein (seldane)

  • an antihistamine

  • caused heart complications when taken with erythromycin or ketoconazole


2
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Zantac (Ranitidine)

  • Used for heartburn and acid reflux 

  • Caused dizziness and gastrointestinal distress 

  • Taken off the market because it led to cancer 


3
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Isotretinoin (Accutane) 

  • Serious side effects when taken by pregnant women 

    • Severe abnormalities in birth 

    • Depression, psychosis, IBS


4
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Omniflox (Temafloxacin)

  • Recalled only 6 months after approval 

  • Used to treat bacterial infections 

  • Reports of severe responses: 

    • low blood sugar

    • Kidney malfunction 


5
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Bromfenac (Duract)

  • a painkiller

  • resulted in: 4 deaths, 8 liver transplant, 12 cases of serious liver damage, Severe jaundice and hepatitis


6
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Able Labs

  • Closed in 2005 

  • Manufacturing quality concerns: 

    • Too low of doses 

    • Too high of doses

    • Contamination


7
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Troglitazone (Rezulin)

  • An anti-inflammatory and anti-diabetic drug 

  • Associated with hepatitis 

    • At least 63 deaths and multiple cases of liver failure


8
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Posicor

  • Used to treat hyper tension 

  • Recalled due to the death of 123 people who took the medication 

  • Fatal when taken with other drugs 


9
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Fen-Phen

  • Mixture of fenfluramine and phentermine 

    • Never approved for use together 

  • Miracle weight loss medication 

  • Reports of severe lung issues → pulmonary hypertension 


10
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Diethylstilbestrol (DES)

  • Minimized risk of miscarriage

  • Caused vaginal cancer in girls exposed to it in the womb


11
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Vioxx (Rofecoxib)

  • A pain reliever for arthritic pain

  • Raised risk of stroke or heart attack 

  • Voluntarily recalled 


12
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Thalidomide (Immunoprin)

  • A sedative to alleviate morning sickness 

  • Causes severe birth defects

  • Bad for pregnant women


13
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Tylenol (Acetaminophen) 

  • Recalled due to product tampering (1982) 

  • Recalled due to musty odor caused by TBA presence and quality control issues (2010) 


14
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Duloxetine

  • Antidepressant 

  • Contains higher-than acceptable levels of nitrosamines 

    • Increased cancer risk over long period of time