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Where is oxytocin synthesised?
supraoptic and paraventricular nuclei of the hypothalamus
Where is oxytocin stored and released?
posterior pituitary gland
What are the main effects of oxytocin?
stimulates myoepithelial contractions in the uterus during childbirth
stimulates milk ejection from lactating mammary gland (suckling is a major stimulus for release)
What triggers oxytocin release?
childbirth
breast feeding
physical touch
exercise
listening to music
orgasm/sexual arousal
What type of feedback loop does oxytocin have?
positive feedback loop
For childbirth and breastfeeding, oxytocin release creates a positive feedback loop: the hormone causes an action (contraction/milk let-down), which stimulates more oxytocin release, intensifying the effect until the trigger stops.
What can suppress oxytocin release?
relaxin; This hormone acts in the brain to inhibit oxytocin release, helping to prevent premature uterine contractions, especially around childbirth.