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o2 carrying capacity
hb (g/dL) x 1.34 = mL of o2 / 100 mL blood
raw hematocrit
(total rbc volume/ total blood volume) x 100
true hematocrit
raw hct x 0.96
lambert-beer law
A1/C1=A2/C2
MCV (average rbc size)
80-100 fL
MCH (average hb inside a single rbc)
27-31/32 pg
MCHC (average hb concentration of rbc)
32-36%
RDW (rbc variation)
11.5-14.5%
platelets
150-400 × 103/ uL
WBC
about 4.5-11 × 103/ uL
Hb
male 15-16 g/dL; female 13-14 g/dL
Hct
male 42-52%; female 37-47%
PT (clotting time)
11-13 sec; extrinsic + common
INR
0.8-1.2 normally; warfarin monitoring
aPTT
intrinsic + common; heparin monitoring
vitamin k factors
ii, vii, ix, x
universal rbc donor
O-
universal rbc recipient
AB+
rhoGAM (injection of Rh immunoglobulin)
28 weeks + within 72 hours after Rh+ delivery
hypertonic
water leaves cell; shrink/ crenate
hypotonic
water enters cell; swell, possibly lyse
isotonic
no net volume change
NaCl
mw = 58.44; dissociation factor 2
glucose
mw = 180; dissociation factor 1
pepsin optimum
pH 2 at 37 C
PTU
blocks thyroid hormone → TSH rises → goiter