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Functions of the Skin
protection → from trauma and pathogens & UV radiation
waterproofs skin
sweating regulates body temperature
layers of the skin
epidermis, dermis, hypodermis
layers of epidermis
stratum basale (bottom layer), stratum lucidum (middle layer), stratum corneum (top layer)
what does the stratum basale include
superior to dermis
constantly dividing cells that go up to the dermis each division and then eventually die off because there is no blood supply
melanocytes present (pigment cells)
sensory receptors here (pain & temp sensations)
tactile cells → touch receptors
what does the stratum lucidum include
calluses form here
only in thick skin areas
protection from friction
what does the stratum corneum include
flat hard cells
keratinization occurs here → living skin cells turn into tough, dead, waterproof protein filled cells
protects body from water loss and gives barrier to microbes
What does the dermis include
thickest layer of the skin
sebaceous glands
dermal papillae
hair
arector pili
dense connective tissue
sweat glands
blood vessels
what are sebaceous glands
duct empties into follicle so hair follicle and sebaceous gland is connected
secrete sebum
lubricates hair and skin
waterproofing
kills bacteria
acne caused by inflammation
what is the dermal papillae
connects to epidermis
fingerprints
little bump stuff
what is hair
follicles in dermis
initially fed by blood supply
cells pushed to the top and die
root/shaft
alopecia → immune system attacks hair follicles
what is the arector pili
what are dense connective tissue
contains collagen/elastic fibers → keeps skin firm and plump and bounce and allow it to movie with your facial expressions
sweat glands
90cm² on leg
400 cm² on hand & feet
coiled & tubular
lowers body temperature → water holds in heat b/c high specific heat so releasing the water also releases the heat
blood vessels
present causing blushing/pallor/cyanotic
what is in the hypodermis
subcutaneous tissue
loose connective tissue
nerves
adipose
arteries & veins
function —> energy storage, insulation, absorb shock
what is adipose
fat tissue
insulates the body
padding against injury
is hypodermis considered part of the skin
not technically b/c hypodermis acts as a bride and thethers the skin to the underlying fascia, muscles, and bones
made of loose connective tissue & adipose instead of dense cellular layers designed for barrier protection & sensation
1st degree burn
superficial burn
epidermis
redness & pain → pain b/c of the pain receptors
no blistering
ex. moderate sunburn
2nd degree burn
entire epidermis into dermis
blistering → epidermis is pulling away from dermis & there is fluid
enlarges as time passes → heat is pushing the cells/speading them
10-14 day recovery
if deep into dermis 30-105 day recovery
3rd degree burn
full thickness burn
leathery
brown-red color skin
no pain
no sweating or hair growth
all the way from dermis into hypodermis
affects: blood supply, sebaceous glands so no oil, damaging nerves, sweat glands so you can’t regulate temperature
4th degree burn
tissue down to bone so burned through muscle
critical burn patient criteria
automatic → on face (lung damage), hands or feet (joint damage), front of chest near mouth opening
2nd degree burn 25% or more
3rd degree burn 10% or more
4th degree burn any amount
impetigo
contagious bacterial infection
athlete’s foot
fungal infection
itchy dermal skin condition
ringworm
fungal infection
psoriasis
chronic autoimmune disease
possibly hereditary
overactive cell division
pink/red patches w/ scales
excema
inflammation
sensitivity to chemicals
dandruff
increased rate of kerinization
causes flaking & itching
dry skin
can be caused by a yeast that eats oil on the skin
urticaria
hives
allergic reactions
red elevated patches
basal cell carcinoma
common type of skin cancer
UV radiation
immune system suppresses
surgical removal
recurrence is common
on surface of skin so epidermis → less serious b/c of this and doesn’t spread
to check → check margins for cancer cells and if clear no cancer
squamous cell carcinoma
excessive UV exposure
metastasis (can spread to nearby organs)
melanoma
melanocytes with cancer
spilled ink spot
irregular mole
skin around mole is red
ABCDE
A → asymmetry
B → border
C→ color
D → diameter
E → evolving
kaposi’s sarcoma
skin cancer seen in AIDS patients
b/c of decreased immune system
responds to AIDS cocktail
moles
overgrowth of melanocytes
usually not cancerous
warts
viral infection
process of skin healing
hemostatis, inflammation, growth & rebuilding, strenghtening
hemostasis
stopping the bleeding → blood cells clump together and clot protecting the wound and preventing further blood loss
inflammation
once closed w/ clot blood vessels open a bit and allow fresh nutrients and oxygen into the wound for healing
white blood cells called macrophage take on role as wound protector and fight infection and oversees repair process
growth & rebuilding
blood cells arrive to help build new tissue
chemical signals tell cells to create collagen
scar eventually dulls from its red state
strengthening
tissue gets stronger → stretching, itching, & puckering of the wound
hair follicle
surrounds the hair root so in epidermis and dermis
hair root
inside follicle and extends down into dermis
hair shaft
visible part that extends out of the body surface
sweat glands
blood vessels
decubitus ulcers (bed sores)
decreased blood flow
areas with little fat and muscle over bony prominences are common sites
developed from pressure, shear (when two parallel forces move in opposite directions) and friction
lipsuction
fat removed from the body
taking the fat out of the hypodermis
popular areas: thighs, buttocks, abdomen and neck
10-15 lbs generally taken off
tattoos
ink into dermis b/c the epidermis skin falls off
tattoo removal → breaking the ink into smaller particles so the body eats it up
complications from burns
fluid loss → b/c of blisters, happens soon as pass 1st degree
heat loss → skin more open so lose heat
infection
rule of 9s
each entire arm (not hands) → 9%
each entire leg → 18%
perineum → 1%
entire torso + chest combo → 36%
entire head → 9%
healing of burns
dead skin removed
skin grafting → autografts, allografts
autografting
taking skin from own body
pros: permanent, body will accept it
cons: scarring, second wound site that has to heal
use for: deep partial/full thickness burns
allogradting
taking skin from other body
pros: readily available, can get a lot of skin
cons: body could reject it, temporary
use for: temporary wound coverage, when autograft isnt available
nails
special epithelial cells at base
visible part is nail body which is pink & vascular
grows 1mm/week
cuticle → thin layer of dead skin that is waterproof and protects underlying nail from bacteria, dirt, & infections
lunula → crescent shape thick layer of reproducing cells
thicker skin characteristics
offer more protection
has thicker stratum coreum and epidermis
no hair follicles and sebaceous glands
contains less sweat glands
less flexible
how does epidermis get oxygen & nutrients
from capillaries in dermis
oxygen & nutrients diffuse upward into the living skin part of the epidermis (stratum basale)
why cant full thickness burn heal on their own
affects all skin layers so there is no healthy skin to regenerate
blood vessels and nerve endings are destroyed so no oxygen and nutrients and those r needed for repair
why elevate burns?
to reduce fluid buildup and swelling
why r third degree burns not painful
b/c pain receptors/nerves r burned off
broad spectrum antibiotic
protection from infections and different kinds of bacteria, all around protection
escharotomy
surgical procedure where doctor cuts through the hard burn layer to relieve dangerous pressure
lymphatic system in wound healing
gives O2, nutrients, clotting proteins
integumentary system in wound healing
forms primary physical barrier against infection by traveling across wound and forming a protective epithelial layer
why heat helpful in wound healing
accelerates cellular activities so wound heals faster
types of wounds
abrasions, lacerations, puncture wounds, avulsions
abrasians
scrape where epidermis is rubbed off by rough surface
lacerations
deep cut/tear in skin w/ jagged/irregular edges
puncture wounds
deep narrow wound caused by sharp pointed object piercing the skin
avulsions
partial or complete piece of skin and underlying tissue forcibly torn away from the body