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IV Hydration Solutions
Isotonic
Hypotonic
Hypertonic
Isotonic IV Solution Water movement/effect
Expands extracellular volume without major tonicity-driven cell shef
Isotonic IV Solution Examples
0.9% Saline (Normal Saline)
Lactated Ringer (LR)
Isotonic IV Solution Use
Replace volume lossess; watch for overload
Hypotonic IV Solution Water movement/effect
Lower effective particle concentration than body fluids; cells swell
Hypotonic IV Solution Examples
0.45% saline
Hypotonic IV Solution Use
Selected water deficits / Hypertonic dehydration
Hypernatremia after stabilization
Can worsen cellular swelling or hypotension
Hypertonic IV Solution Water movement/effect
Pulls water from cells into extracellular space; Cells shrink
Hypertonic IV Solution Examples
3% saline; D10W and dextrose-saline mixtures are hyperosmolar in the bag
Hypertonic IV Solution Use
Product-specific indications; hypotonic dehydration; 3% saline for selected severe symptomatic hyponatremia.
IV Complication Recognition
Phlebitis
Infiltration
Extravasation
Infection
Circulatory Overload
Phlebitis
Inflammation of the blood vessels
Phlebitis Clues
Warmth, pain, redness along vein; possible cord
Infiltration
leakage of a non vesicant IV fluid or medication out of the vein into surrounding tissue.
Infiltration Clues
Cool, pale, swollen, painful IV site
Extravasation
leakage of a vesicant IV fluid or medication out of the vein into surrounding tissue (Infiltration but IV Fluid itself causes tissue damage aswell as leakage)
Extravasation Clues
Burning, swelling, pain; tissue injury risk
Infection
Microorganisms enter and multiply at the IV site or in the bloodstream
Infection Clues
Redness, warmth, drainage, fever
Circulatory Overload
Too much fluid in the bloodstream for the body to handle, potentially causing fluid buildup in the lungs.
Circulatory Overload Clues
Dyspnea, crackles in lungs, HTN, edema
Phlebitis Response
Stop/discontinue affected peripheral IV; warm compress and further care per policy
Infiltration Response
Stop infusion, manage site, and elevate per policy
Extravasation Response
Stop infusion, do not flush. Retain catheter initially for aspiration/antidote as directed; notify and follow drug specific protocol
Infection Response
Assess, stop/use alternate access as indicated, notify, cultures/treatment per protocol
Circulatory Overload
Stop/adjust fluid per emergency protocol, assess ABCs, elevate HOB, oxygen and notify
Before Blood Transfusion
Verify the order and signed informed consent
Establish baseline
Bedside verification by two qualified staff members
Gather equipment
Blood Transfusion Equipment
Appropriate patent IV
Blood administration tubing/filter
0.9% Normal Saline to prime and flush
Adult peripheral 20-22 gauge
Blood can be given through suitiable
20-22 gauge adult access
Blood Transfusion Timing
After issuing of blood from blood bank
First 15 minutes
After first 15 minutes
Completion
After issue from blood bank
Be ready before obtaining blood.
Start within 30 minutes of acquiring
Do not store blood in an ordinary unit refrigerator
First 15 Minutes
Start slowly; the textbook example is about 2 mL/min (120 mL/hr)
Stay with the patient
Observe closely and measure vital signs every 5-15 minutes
After first 15 minutes
If no reaction, increase to the prescribed rate
Continue assessing symptoms and vital signs every 1-2
Blood Transfusion should be completed within
4 hours of removal from blood-bank refrigeration
Completion
Flush with normal saline, obtain final vital signs, evaluate response, and handle tubing/bag per policy
If you suspect a transfusion reaction
STOP THE TRANSFUSION IMMEDIATELY!!!!!!!!!!
Assess ABCs, vital signs, SpO2, lung sounds and symptoms (call RRT)
Maintain IV access with normal saline through NEW tubing
Notify the provider and blood bank
Follow the reaction protocol
Document
Transfusion Complications
Acute hemolytic reaction
Febrile nonhemolytic reaction
Allergic/anaphylactic reaction
Bacterial Contamination
TACO: circulatory overload
TRALI
Acute Hemolytic
Fever / chills, back / chest pain , dyspnea, hypotension, dark urine; risk of shock / renal injury
Febrile nonhemolytic
Temp rises/chills; first exclude serious causes rather than assuming harmless fever
Allergic / anaphylactic
Itching / hives; severe cases include wheeze, airway swelling, hypotension
Bacterial contamination
High fiver, rigors, GI symptoms, hypotension/sepsis
TACO: Transfusion-Associated Circulatory overload
Dyspnea, pulmonary edema, often hypertension/JVD and excess volume
TRALI: Transfusion-Related Acute Lung Injury
Acute Hypoxemia and lung injury without primary circulatory overload, during or within 6 hours
Packed Red Blood Cells
Increase hemoglobin and oxygen-carrying capacity; still add fluid volume
Platelets
Treat low platelets/platelet dysfunction
Plasma
Supplies clotting factors
Cryoprecipitate
Supplies fibrinogen and selected clotting proteins
Whole blood
Used in selected major bleeding situations
Universal Donor
O-
Universal Recipient
AB+