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the bodt must use one of three energy systems to produce the energy which is required to resynthesise ATP from ADP + Pi
ATP-PC system
Glycolytic system
Aerobic system
ATP-PC system
resynthesises ATP from breakdown of phosphocreatine
glycolytic system
resynthesises atp from the breakdown of glycogen
aerobic system
resynthesises ATP from the breakdown of glycogen, glucose and free fatty acids
site of reaction in ATP-PC
cytoplasm of a muscle cell
what chemical does it use
produces energy by breaking down phosphocreatine
the energy and phosphate molecule released from the breakdown of PC are then used to resynthesise 1 ATP and 1 ADP
what is the enzyme used in the ATP-PC system
creatine kinase
is the ATP-PC system aerobic or anaerobic
anaerobic system
therefore supplies energy for actions such as sprinting
ATP yield from the ATP-PC system
1 ATP molecule
time frame from ATP-PC system
up to 10 secs of exercise
due to limited stores of PC in the body
by products of ATP-PC system
no by products
what is the ATP-PC system used for
used to provide energy very quickly, as PC is readily available and doesn’t require oxygen to be delivered
process of ATP-PC system
system kicks in after high intensity exercise after 1st 2 secs depletes original stores of ATP
ATP levels fall dramatically and ADP + PI levels increase
triggers the release of creatine kinase which triggers the breakdown of the immediately available fuel phosphocreatine (PC)
PC is made up of creatine with a high energy phosphate bond and is stored in muscle cells
bond is broken which releases energy for ATP synthesis
every one mol of PC broken down, one mol of ATP is resynthesized
when does the glycolytic system kick in
used to produce energy once the PC stores have been used up when performing anaerobically
where does the glycolytic system take place
in the cytoplasm of a muscle cell
what type of reaction is the glycolytic system
anaerobic
(if it has oxygen it goes to aerobic)
what is the chemical used in the glycolytic energy system
glucose in the blood
or glycogen
what is the controlling enzyme for glycolytic system
as ADP + Pi levels rise, an enzyme is released which catalyses the breakdwon of glucose in the blood
phosphofructokinase (PFK)
what happens if glucose levels in blood are low
glycogen (stored glucose in muscle cells) is broken down by an enzyme
glycogen phosphorylase (GPP)
to retaain concentration of glucose back in blood
what happens in glycolytic system if there is no oxygen available
glucose is used as a fuel and broken down to continue the resynthesis of ATP in the cytoplasm
a process called anaerobic glycolysis
ATP yield from glycolytic system
2 ATP molecules
actual products from glycolytic system
glucose is converted into pyruvic acid
2 ATP mols
NADH is by-product
by products from glycolytic system
NADH
lactic acid
duration of glycolytic system
2-3 mins
process of glycolytic system
kicks in during high intensity activity after first 10 secs exhausts the PC stores and ATP levels fall- ADP + P levels will increase again
this triggers the release of PFK-catalyses the breakdown of glucose
if low glucose- GPP catalyses the breakdown of stored glycogen
anaerobic glycolysis results in production of pyruvic acid
one molecule of glucose= 2 ATP produced
consequences of glycolytic system peaking at 1 min at falling at 3
at high intensity, oxygen is not available to continue the energy extraction from pyruvic acid
lactate dehydrogenase is released
this is a enzyme which catalyses the conversion of pyruvic acid into lactic acid which accumulates and slows ATP synthesis
problems with anaerobic glycolysis
frees only 5% of potential energy held in glucose molecule
lactic levels rising= pH decrease and acidity increases
this inhibits enzyme activity preventing further breakdown of fuel and ATP resynthesis, causing local muscular fatigue
point at which blood lactate levels significantly rise is known as OBLA
what occurs in the glycolytic system if oxygen is available
the final stage of glycolic energy system will involve pyruvic acid being converted to acetyl CoA (instead of lactic acid)
this will enter krebs cycle of aerobic system
what type of reaction is the aerobic system
aerobic
what chemicals are used in aerobic system
glucose
glycogen
triglycerides/ fats
site of aerobic system
mitochondria
specifically cytoplasm, matrix and cristae
controlling enzyme for aerobic system
GPP
PFK
acetyl coenzyme A
lipase
ATP yield from aerobic system
2 ATP from aerobic glycolysis
2 ATP from krebs cycle
34 ATP from electron transport train
38 overall
by products of aerobic system
carbon dioxide
water
what are the 3 stages in the aerobic system
aerobic glycolysis
krebs cycle
electron transport chain
aerobic glycolysis
in cytoplasm converts glucose into pyruvic acid with the enzyme PFK
releases enough energy to resynthesise two moles of atp
converting glycogen into glucose (by GPP) maintains this process for extended periods of time
oxygen is now in sufficient supply, the pyruvic acid is no longer converted into lactic acid
goes through link reaction catalysed by coenzyme A which produces acetyl CoA
krebs cycle
acetyl CoA combines with oxaloacetic acid to from citric acid which is oxidised through a cycle of reaction
co2, hydrogen and enough energy to resynthesise 2 mols of ATP are released
occurs in the matrix of mitochondria
electron transport chain
3rd stage of aerobic system producing enough energy to resynthesise 34 ATP in the mitochondrial cristae
aerobic system and FFAs
glycogen stores can fuel the system for a long time
triglycerides or fats can also be metabolised as free fatty acids (FFAs) which provide a huge potential fuel store
on the release of lipase- responsible for breaking down fats and triglycerides- they are converted into ffas and glycerol.
ffas converted to acetyl coa and follow the same path through krebs and etc and pyruvic acid
total number of ATP released in aerobic system
2 from aerobic glycolysis
2 from krebs
34 from electron transport chain