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Synaptic Transmission
Process of transferring information across a synapse.
Synapse
Junction where one neuron communicates with another neuron or target cell.
Who coined the term synapse?
Charles Sherrington in 1897.
Who demonstrated chemical synaptic transmission?
Otto Loewi in 1921.
Who helped demonstrate electrical synaptic transmission?
Furshpan and Potter in the late 1950s.
Presynaptic Neuron
The sending neuron that releases neurotransmitter.
Postsynaptic Neuron
The receiving cell containing neurotransmitter receptors.
Direction of Information Flow in Most Synapses
From presynaptic neuron to postsynaptic cell.
Electrical Synapse
Connection between cells through gap junctions allowing direct ion flow.
Major Advantage of Electrical Synapses
Extremely fast transmission.
Direction of Electrical Synapses
Usually bidirectional.
Gap Junction
Direct channel connecting two cells.
Connexin
Protein subunit that forms a connexon and enables direct cell-to-cell communication and metabolic support
Connexon
Channel composed of six