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Deviations from the typical chromosomal structure are called
chromosomal aberrations
Aberrations may be caused by problems during
meiotic recombination or during DNA break repair
Breakage and rearrangement may occur
spontaneously within an individual, or the altered chromosome may be inherited from a parent
Inversion
Broken chromosome part joins it again but is turned around 180 degrees

Translocation
Non homologous chromosomes exchange segments

Deletetion
The chromosome fragment breaks down

Duplication
Chromosome segments double
