FINALS: RBC Disorders (3)

32P treatment

Which treatment is described as having radiation issues among its disadvantages?

Antimetabolite

Hydroxyurea is classified as which type of drug?

DNA

Hydroxyurea inhibits the synthesis of which molecule?

Chronic myeloid leukemia (CML)

Which condition is listed as a use of hydroxyurea?

Sickle cell disease

Which blood disorder is listed as a use of hydroxyurea besides CML and PV?

It reduces spleen size

Which is an advantage of hydroxyurea listed?

Close monitoring is needed

Which is a disadvantage of hydroxyurea?

Daily medication compliance

Which practical issue is associated with hydroxyurea treatment?

Gastrointestinal (GI) toxicity

Which toxicity is described as rare with hydroxyurea?

Hydroxyurea

Compared with 32P, which treatment is noted to have a low leukemia risk in the slide's advantages?

Anemia of bone marrow failure

Aplastic anemia is placed under which broad category?

Pancytopenia

Which blood-count pattern is associated with aplastic anemia?

Hypoplastic

How is the marrow described in aplastic anemia?

Primary and secondary

Which classification is listed for aplastic anemia?

Fanconi anemia

Which congenital condition is mentioned under primary aplastic anemia?

Chloramphenicol

Which drug is listed among possible causes of secondary aplastic anemia?

Chlordane

Which insecticide is listed among chemicals associated with secondary aplastic anemia?

Chlorophenotane (DDT)

Which chemical name is listed alongside chlordane?

Gold preparations

Which preparation is included among drug-related causes of secondary aplastic anemia?

Hydantoins

Which drug class is listed among causes of secondary aplastic anemia?

Sulfonamides

Which additional drug class is listed as a possible cause of secondary aplastic anemia?

Radiotherapy

Which radiation exposure is listed as a cause of secondary aplastic anemia?

Radioactive isotope administration

Which medical exposure is listed under radioactive causes of aplastic anemia?

Immune mechanisms

Which mechanism is included among causes of secondary aplastic anemia?

Non-A, non-B (NANB) hepatitis

Which infection is specifically listed as a possible cause of secondary aplastic anemia?