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what is the function of the skeletal system?
support, protection, production of blood cells, storage of inorganic materials
how are bones classified?
shape
what are the classifications of bones (+ examples)?
long (femur)
short (wrist)
flat (pelvic)
irregular (vertebrae)
sesamoid (knee cap/patella)
what is the epiphysis?
expanded portion at the end of the bone that forms the joint
what is the epiphyseal disk?
the growth plate (thin line of cartilage)
what is the diaphysis?
the shaft of the bone
what is the medullary cavity?
the hollow camber in the center of the diaphysis
what is spongy/cancellous bone?
lighter bone that is found in the epiphysis
what is compact bone?
dense, tightly packed bone that surrounds the entire bone for strength and protection
what is the periosteum?
tough exterior of the bone that is vascular and nerve-covered
what is the endosteum?
membrane of osteoblasts on the walls of the medullary cavity
what is articular cartilage?
layer of hyaline cartilage on the epiphysis
what is red marrow? where is it found?
forms red and white blood cells and platelets
flat bones and epiphysis of long bones
what is yellow marrow? where is it found?
stores fat
diaphysis
what is a perforating/Volkmann’s canal?
horizontal canals that connect central canals in compact bone
what is a central/Haversian canal?
vertical canals with blood vessels and nerves in compact bone
what is an osteon?
a circular unit of bone that surrounds a central canal
what makes up an osteon?
calcified rings of lamella
what are triabecula?
plates of bone in spongy bone that make it lighter
what are canaliculi
canals between osteocytes in spongy and compact bones
what are osteoblasts?
bone building cells which deposit Ca and P into dense collagen framework and eventually become osteocytes
what are osteoclasts?
large, multi-nucleated cells that secrete acid to break down bone matrix
what is the purpose of osteoclasts?
help with releasing Ca and P into the bloodstream, bone remodeling, and resorption
what occurs when there is too much calcium in the bloodstream?
thyroid gland senses and releases calcitonin which tells osteoblasts to pull Ca into bones
what occurs when there is not enough calcium in the bloodstream?
parathyroid gland senses and releases parathyroid hormone which tells osteoclasts to break down bone
what type of bone does intramembranous ossification form?
flat bone
what does intramembranous ossification do?
changes mesenchymal (undifferentiated) tissue into bone
what are the steps to intramembranous tissue?
layers of undifferentiated connective tissue appear at sites of future bone
connective tissue cells differentiate into osteoblasts around blood vessels
osteoblasts become osteocytes when completely surrounded by bony matrix
connective tissue on the surface forms the periosteum
what are the steps of endochondral ossification?
hyaline cartilage model forms at the site of future bone
cartilage cells die in lacunae
blood vessels come in with osteoblasts which add Ca and P to cartilage
osteoblasts become osteocytes when completely surrounded by bony matrix
what is the primary ossification center?
first point that develops into bone
what is the secondary ossification center?
appears in epiphysis last to form endochondral bone
why is a primary and secondary ossification center necessary in endochondral ossification?
to form the growth plate between the diaphysis and epiphysis
what are the four layers of the growth plate?
resting zone
proliferation zone
maturation & hypertrophy
calcified matrix