OChem Functional Groups and pKas

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Last updated 4:39 AM on 10/18/26
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24 Terms

1
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alkyl halide/halo group

R — X, halogen attached

<p>R — X, halogen attached</p>
2
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hydroxyl group

R — OH

<p>R — OH</p>
3
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ether/alkoxy group

R — OR

<p>R — OR</p>
4
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amine/amino group

R — NH2, R2NH, R3N

<p>R — NH2, R2NH, R3N</p>
5
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thiol/thio group

R — SH

<p>R — SH</p>
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sulfide/thioether/alkylthio group

R — S — R

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carboxy group

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cyano group

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nitro group

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pKa < 0

oxygen with triple bond, attached to at least one H

<p>oxygen with triple bond, attached to at least one H</p>
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pKa = 5

carboxylic acid

<p>carboxylic acid</p>
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pka = 10

protonated amines

<p>protonated amines</p>
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pKa = 15

alcohol and water

<p>alcohol and water</p>
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pKa = 25

alkines

<p>alkines</p>
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pKa = 35

ammonia family, amines

<p>ammonia family, amines</p>
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pKa = 45

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pKa = 50

hydrocarbon chains

<p>hydrocarbon chains</p>
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aldehyde

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ketone

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carboxylic acid/carboxyl group

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ester

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amide

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acid chloride

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anhydride

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