Key Drugs P2 Fall -- Side effects, renal adjustments and counseling

ACE inhibitors

Cough, hypotension, dizziness, hyperkalemia, renal adjustment

Norepinephrine bitartrate

Bradycardia, arrhythmia, anxiety, headache

Epinephrine

Anxiety, disorientation, headache, restlessness

Dopamine HCl

Tachycardia, arrhythmias, excessive vasoconstriction

Doxazosin

Orthostatic hypOtension, tachycardia, sexual dysfunction

Clonidine

Drowsiness, headache, dizziness, rash, dry mouth

ARBs

Dizziness, fatigue, hypOtension, headache, hyperkalemia

Adenosine

Immediately after administration: sudden and transient chest pressure and sense of impending doom

Amiodarone

Epithelial keratopathy (eyes), hypOtension, N/V

Flecainide

Dizziness, ventricular arrhythmias, visual disturbances

Atropine

Drying, constipation, dizziness, drowsiness

Heparin sodium, unfractionated

Bleeding, osteoporosis, thrombocytopenia

Vasopressin

Drink 1-2 glasses of water when given to reduce nausea/cramps

Clopidogrel

Hemorrhage, bruising, hematoma

Beta blockers

Bradycardia, hypOtension, fatigue

Which beta blocker is renally adjusted and can lead to supraventricular tachycardia

Atenolol

Which beta blocker can lead to bronchospasm or sleep disorders?

Propranolol

Diltiazem

HF exacerbation (edema, SOB), bradycardia, hypotension, constipation, headache, serious skin reactions weeks after starting

Verapamil HCl

Constipation, edema, headache

Amlodipine

Edema, fatigue, headache, flushing, hypOtension

Nifedipine ER

Edema, fatigue, headache, flushing, hypOtension, avoid grapefruit

Digoxin

Nausea, dizziness, fatigue, yellow halos in vision, renally adjusted

Lidocaine HCl (injection)

Headache, bradycardia, hypOtension

Argatroban

Bleeding

Rivaroxaban

Bleeding, hemorrhage, vomiting, cough, rash, abdominal pain, renally adjusted

Apixaban

Bleeding, hemorrhage, renally adjusted

Magnesium sulfate

Flushing, hypOtension, vasodilation

KCl

Bradycardia, chest pain, skin rash, abdominal pain

Phytonadione

Dizziness, flushing, hypOtension

Fenofibrate

Abdominal pain, myopathy, renally adjusted

Statins

Diarrhea, myalgia, avoid grapefruit juice

Which statin needs to be renally adjusted

Rosuvastatin

Loop diuretics

Electrolyte abnormalities, dizziness, frequently urination

Enoxaparin sodium

Anemia, hemorrhage, renally adjusted

Scubitril/valsartan

HypOtention, dizziness, cough, renally adjusted

Aspirin

GI ulcer, hypersensitivity

Evolocumab

injection site reactions, flu-like, headache, nasopharyngitis

Spironolactone

Gynecomastia, frequent urination, with or without food but same way each time

Triamterene

Dizziness, fatigue, hypOtension, headache, hypERkalemia

Ezetimibe

Myalgia, arthralgia

Chlorthalidone

Dizziness, hypOtension, frequent urination

HCTZ

Electrolyte abnormalities, dizziness, hypOtension, frequent urination

Alteplase

Bleeding

Hydralazine

Lupus like syndrome, edema, flushing

Isosorbide mononitrate

Headache, hypOtension, bradycardia, dizziness

Sodium nitroprusside

Bradycardia, ECG changes, dizziness, headache, renally adjusted

Warfarin

Bleeding, bruising, hemorrhage, consistent vitamin K intake

Naphazoline HCl (ophthalmic)

Pupil dilation, irritation

Phenylephrine HCl

Flushing, loss of appetite, restlessness, use for less than 7 days

Brimonidine tartrate (ophthalmic)

Drowsiness, eye itching, blurred vision, light sensitivity

Benzoyl peroxide

Skin peeling, redness, contact dermatitis, dryness, bleaching of skin or cloth

Tolnaftate

Itching, stinging

Ketoconazole

Itching, burning, dryness

Miconazole nitrate

Itching, burning, dryness

Tacrolimus

Itching, burning, redness, avoid excessive sunlight

Carbamide peroxide (otic)

Irritation, redness, rash

Clobetasol propionate

Burning, nasopharyngitis, UR infection

Hydrocortisone

Burning, irritation, redness, dryness, even itching

Methylpredisolone (oral)

Insomnia, increased appetite, mood changes, nausea, take with food

Predisolone sodium (oral)

Insomnia, increased appetite, mood changes, nausea, take with food

Prednisolone acetate (ophthalmic)

irritation

Prednisone

Insomnia, increased appetite, mood changes, nausea, take with food

Triamcinolone acetonide

Irritation, rash, itching, burning, dryness

Adalimumab

injection site reaction, rash, headache, UR infection

Infliximab

Abdominal pain, nausea, abscess, headache, cough, flushing

Ofloxacin (otic and ophthalmic)

Burning, stinging, itching, blurred vision

Hydroxyzine HCl and pamoate

Drowsiness, dizziness, dry mouth, itching

Olopatadine HCl (ophthalmic)

Headache, blurred vision

Ketotifen fumarate (ophthalmic)

Local irritation, redness

Dupilumab

injection site reactions, conjunctivitis, dry eyes

Salicylic acid

Burning, irritation

Lidocaine HCl (topical)

Skin blanching, hypersensitivity

Pramoxine HCl

Tingling/numbing

Timolol maleate (ophthalmic)

Burning, stinging, blurred vision

Latanoprost

Eye pain, irritation

Tretinoin

Dryness, redness, peeling, irritation, avoid excessive sun exposure

Adapalene

Dryness, redness, irritation, avoid excessive sun exposure

Nicotine gum

throat irritation, abnormal dreams, flatulence, headache, insomnia

Nicotine patches

Abnormal dreams, flatulence, headache, insomnia

Bacitracin, neomycin, polymixin B

Side effects are rare

Gauifenesin

Headache, stomach pain, nausea, take with glass of water/maintain hydration

Chlorpheniramine maleate

Drowsiness, dizziness

Dextromethorphan

Dizziness, drowsiness, nervousness, restlessness

Sodium bicarbonate

Flatulence/eructation (burping), edema

Sodium chloride

Acid-base imbalance