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PNS is split into
sensory division and motor division
motor division is split into
somatic and autonomic
autonomic is split into
sympathetic, parasympathetic, and enteric
multipolar
multiple dendrites, one axon, ex. motor neurons and interneurons
bipolar
1 dendrite, 1 axon, sensory neurons like auditory, visual, vestibular neurons
pseudounipolar
peripheral process and central process, sensory non-bipolar like muscle spindles and cutaneous afferents
nerve
collection of axons/neuronal cell processes in PNS, will have supportive cells (schwann cells) and CT cells (fibroblasts)
tract
collection of axons/neuronal cell processes in CNS
ganglion
collection of neuron cell bodies in PNS
nucleus
collection of neuron cell bodies in CNS
groups of neurons
primary afferent neurons, final efferent neurons, interneurons, projection neurons
primary afferent neurons
conduct pulses from periphery to the CNS
final efferent neurons
conduct impulses from CNS to periphery, lower motor neurons, a,b, y, and autonomic
alpha final efferent neuron
intrafusal fibers in muscle spindle
beta final efferent neuron
extrafusal fibers in muscle spindle
y final efferent neuron
innervate both fiber types
primary afferent neurons and final efferent neurons together form _
reflex arcs/pathways
interneurons
short neurons interposed between afferent synpase and efferent cell body, completely in CNS, may be excitatory or inhibitory but synapses with both
withdrawal reflex
does not need pain, happens locally without brain involvment only spinal cord
projection neurons
in the CNS, can be ascending (spinal cord to brain) or descending (brain to spinal cord) which are known as upper motor neurons
functional types of neurons
based on region of body supplied: GSA, GSE, GVA, GVE
based on direction of impulses: SSA, SVA, SVE
general somatic efferent
multipolar neurons that supply most skeletal muscles, extends ffrom CNS to muscle fibers
general visceral efferent
multipolar neurons that supply smooth muscle, cardiac muscle, and glands, form autonomic nervous system, have two neuron chain between CNS and effector organ
special visceral efferent
multipolar neurons that supply skeletal muscle that are derived from branchial arches (face, neck, shoulders), single neuron from CNS to muscle fibers
general somatic afferent
pseudounipolar neurons that carry sensory info from somatic body systems, cell bodies in sensory ganglia/dorsal root ganglia
general visceral afferent
pseudounipolar neurons that carry sensory info from visceral body systems, cell bodies in sensory ganglia/dorsal root ganglia
special somatic afferent
bipolar neurons that carry visual and auditory information
special visceral afferent
bipolar and pseudounipolar neurons that carry taste and smell information
_ join to form spinal nerve that divides into _
dorsal root and ventral root, dorsal branch, ventral branch, and communicating branch
dorsal and ventral roots are broken down into _
rootlets
_ pairs of spinal nerves
31
cervical spinal nerves
8 pairs, cranial to corresponding vertebrae
thoracic and lumbar spinal nerves
13 and 7 pairs, caudal to corresponding vertebrae
where does c1 come from
lateral vertebral foramen
sacral spinal nerves
3 pairs, from dorsal and ventral sacral foramina
_ pairs of cranial nerves
12
what is the main nerve with autonomic system?
general visceral efferent, but also general visceral afferents and hypothalamus
autonomic
self rule, controls smooth muscle, cardiac muscle, and glands, 2 neuron system, originates in lateral horn of cranial nuclei, target is visceral organ, neurotransmitters are Ach and NE
somatic division
general somatic efferent, 1 neuron system, originates in ventral horn, target is skeletal muscle, neurotransmitter is Ach
sympathetic division
2 neurons, short-long, originates in lateral horn of thoracolumbar segments of spinal cord, neurotransmitters are Ach and NE, ganglia is chain/paravertebral or prevertebral
pre-vertebral ganglia
will be long-short
parasympathetic division
2 neuron system, long-short, originates in cranio sacral region, has brain stem and spinal cord nerves, neurotransmitters are Ach and Ach, ganglia is terminal (in body wall)
brain stem nerves of parasympathetic system
III - ocular motor, VIII - facial, IX - glossopharyngeal, X - vagus
sacral spinal cord nerve of parasympathetic
pelvic nerve
sympathetic actions with no parasympathetic pair
glucose production by liver, renin secretion by kidney, muscle vessels dilation, constriction of cutaneous and visceral vessels, contraction of piloerector muscles, secretion of sweat glands, lipolysis of adipose cells, adrenal medulla epinephrine secretion
sympathetic vs parasympathetic for eye/pupil, heart, lung bronchioles, gut wall, gut sphincter, bladder detrusor, bladder-urethra smooth sphincter, penis, gallbladder bile & duct, salivary glands, nasal and lacrimal glands
dilation vs constriction, increased rate and force vs decreased rate, dilation vs constriction, decreased motility vs increased motility, constrict vs relax, relax vs contraction, constrict vs relax, ejaculation vs erection, relax vs contract, concentrated viscous saliva vs abundant watery saliva, vasoconstriction vs abundant secretion
rami communicantes/communicating branch
connects spinal nerves to the sympathetic trunk, can be white rami or gray rami
white rami
preganglionic sympathetic axons, only with T1-L2 nerves, whitish due to myelination, similar to entrance ramps on highway
gray rami
postganglionic sympathetic axons, connect to all spinal nerves, grayish due to unmyelinated axons, similar to exit ramps off highway, disperses sympathetic info from thoracolumbar to all body parts
4 ways preganglionic neurons can connect with postganglionic neurons
spinal nerve pathway, post-ganglionic sympathetic nerve pathway, splanchnic pathway, adrenal medulla pathway
what is unique about sweat glands?
they are cholinergic in sympathetic, so neurotransmitters are Ach and Ach
spinal nerve pathway
preganglionic neuron comes from lateral horn out of ventral root, comes through white ramus, then synapses with postganglionic neuron that travels through gray ramus, goes back into spinal nerve, then goes to target tissue
post ganglionic sympathetic nerve pathway
synapses in chain gang, does not go back to spinal nerve, comes out of the ganglia
splanchnic nerve pathway
long pre synaptic neuron that goes through white ramus and synapses in prevertebral ganglion, primarily for visceral organs
adrenal medulla pathway
2 neuron system, synapse in adrenal medulla with post-ganglionic neuron as chromaffin cells that secrete epinephrine and norepinephrine
where are cell bodies of parasympathetic preganglionic neurons?
brain stem nuclei and lateral gray matter of 1st through 3rd sacral segments of spinal cord
ciliary ganglia
near optic nerve, oculomotor preganglionic eyeball muscles
pterygopalatine ganglia
near sphenopalatine foramen, facial preganglionic, nasal mucosa, palate, pharynx, lacrimal glands
four ganglia pairs of parasympathetic cranial outflow
ciliary, pterygopalatine, submandibular, otic
submandibular ganglia
near submandibular ducts, facial preganglionic, submandibular and sublingual glands
otic ganglia
below foramen ovale, glossopharyngeal, preganglionic, parotid glands
vagus nerve
has terminal ganglia so synpase in target organ, preganglionic axons here carry 80% of craniosacral outflow
what all do preglanglonic axons of vagus nerve innervate?
heart, lungs, liver, gallbladder, stomach, pancreas, small intestine, and part of large intestine
sacral parasympathetic outflow
has preganglionic axons from S1-S3 that form pelvic splanchnic nerves
what all do postganglionic axons of pelvic nerve innervate?
colon, ureters, bladder, and reproductive organs
sympathetic innervation to body wall and limbs
preganglionic from lateral horn, will exit out of ventral root and go through spinal nerve and communicating branch and synapse in sympathetic trunk
sympathetic innervation to head, neck, and thorax
preganglionic nerve will enter communicating branch then chain gang and then
thorax: synpase at cervicothoracic ganglion
neck: go around axillary artery as ansa axillaris, and synapse at middle cervical ganglion
head: go around axillary artery as ansa axillaris, go through vagosympathetic trunk, and synapse at cranial cervical ganglion
ansa subclavia
loop around subclavian artery, cardiac nerves come off of it
sympathetic innervation to abdominal cavity
will go through communicating branch and chain gang, will leave as
caudal abdominal cavity: lumbar splanchnic nerve and synapse at caudal mesenteric ganglion
abdominal cavity: major and minor splanchnic nerves and synapse at celiacomesenteric ganglion and plexus
sympathetic innervation to pelvic cavity
will go through communicating branch and chain gang, will leave as lumbar splanchnic nerve and synapse at caudal mesenteric ganglion, post ganglionic nerves are vertebral and hypogastric nerves that will go through the pelvic plexus
parasympathetic innervation to head, cervical, thorax, and abdomen
vagus nerve will split into dorsal and ventral branch, R and L dorsal branches will make a dorsal vagal trunk that goes towards celiacomesenteric plexus, R and L ventral branches make a ventral vagal trunk that goes towards cranial mesenteric plexus
parasympathetic innervation to pelvic cavity
will leave lateral horn and go through ventral root, go through spinal nerve and lumbosacral plexus, leave as pelvic nerve and go through pelvic plexus
what does celiac plexus control?
stomach, spleen, liver, gallbladder, pancreas
what does cranial mesenteric plexus control?
small intestines, cecum, ascending and transverse colon
what does ventral vagal nerve trunk control?
liver and stomach
arterial supply of thoracic limb
subclavian artery → axillary artery → brachial artery → median artery → superficial palmar arch → palmar common digital arch
when does axillary artery become brachial artery?
after cranial circumflex humeral artery comes off
what does caudal circumflex humeral artery supply blood to?
latissimus dorsi
when does brachial artery become median artery?
after common interosseous artery comes off
what is superficial palmar arch formed by?
median artery and superficial branch of caudal interosseous artery
what conects the cephalic vein and the axillary vein?
axillobrachial vein
what connects the cephalic vein and the brachial vein?
median cubital vein
afferent lymph vessels
bring unfiltered lymph from the body to lymph node where it is filtered
efferent lymph vessels
carry filtered lymph to another lymph node, vein, or to a larger lymph duct
terminal lymph node
lymph node which all or most of lymph from a region must drain
sentinel lymph node
first node that drains a particular area and thus the node that is likely to be removed or biopsied in the event of neoplasia/infection
superficial cervical lymph node location
cranial to shoulder joint, covered by brachiocephalicus and omotransversarius
superficial cervical lymph node afferent lymph vessels
skin of caudal portion of the head, part of the ear, lateral surface of neck, most of thoracic limb except for medial side of arm, forearm, and shoulder
superficial cervical lymph node efferent lymph vessels
thoracic duct on left side, right tracheal trunk on right side, external jugular vein on both sides
axillary lymph node location
caudal to shoulder joint, ventral to thoracodorsal vessels and latissimus dorsi, at distal part of teres major muscle
axillary lymph node afferent lymph vessels
first three mammary glands, skin of shoulder and arm, all of bones except digits, humeral, cubital and carpal joints, muscles of thoracic limb, accessory axillary lymph node
axillary lymph node efferent lymph vessels
external jugular vein on both sides, thoracic duct on left side, right and left tracheal trunk
accessory axillary lymph node location
ventral to latissimus dorsi, dorsal to deep pectoral, in the 2nd and 3rd intercostal space
accessory axillary lymph node afferent lymph vessels
first three mammary glands, skin of lateral and ventral thoracic wall, lateral and medial regions of the shoulder, arm, and elbow
accessory axillary lymph node efferent lymph vessels
axillary lymph node
brachial plexus
made up of nerves from C6 - T2
nerves of brachial plexus
suprascapular, subscapular, cranial pectoral, musculocutaneous, axillary, thoracodorsal, radial, median, ulnar, lateral thoracic, caudal pectoral
nerves of brachial plexus that have cutaneous branches
musculocutaneous, axillary, radial, median, ulnar
all brachial plexus nerves have axons for _ and _, and all have _
sensory info and motor info, sympathetic fibers
muscles innervated by suprascapular, subscapular, cranial pector, musculocutaneous, axillary, thoracodorsal, radial, median, ulnar, lateral thoracic, caudal pectoral
supraspinatus, infrapspinatus
subscapularis
superifical pectorals
biceps brachii, brachialis, coracobrachialis
deltoid, teres major, teres minor, (subscapularis)
latissimus dorsi
triceps brachii, extensor carpi radialis, ulnaris lateralis, common digital extensor, lateral digital extensor
flexor carpi radialias, superficial digital flexor, (deep digital flexor)
flexor carpi ulnaris, deep digital flexor
cutaneous trunci muscles and reflex
deep pectoral