cardio b3 ahmed portion

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Last updated 3:18 AM on 10/3/26
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7 Terms

1
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statin mo

  • INHIBIT hmg-CoA → increased LDL synthesis → increased ldl removal


2
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pro-drug statins

lovastatin and simvastatin

3
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PCSK9 moa

inhibits PCSK9 interaction with ldl and reduces ldl degradation

4
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bile acid moa

increased synthesis of bile acids → increases clearance of LDL

5
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precursor of bile acids

cholesterol

6
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bile acid drugs

cholestyramine, colestipol, and colesevelam

7
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niacin moa

reduces cAMP → decreased lipolysis → decreased VLDL and LDL