Lymphoma Translocations and Immunohistochemistry

0.0(0)
Studied by 0 people
call kaiCall Kai
learnLearn
examPractice Test
spaced repetitionSpaced Repetition
heart puzzleMatch
flashcardsFlashcards
GameKnowt Play
Card Sorting

1/15

encourage image

There's no tags or description

Looks like no tags are added yet.

Last updated 2:02 AM on 10/2/26
Name
Mastery
Learn
Test
Matching
Spaced
Call with Kai
Chat

No analytics yet

Send a link to your students to track their progress

16 Terms

1
New cards

t(8;14) disease

Burkitt lymphoma

2
New cards

t(8;14)

Immunoglobulin gene promoter overexpressing proto-oncogene c-myc

3
New cards

t(9;22) disease

CML (required for diagnosis, AML and ALL also possible)

4
New cards

t(9;22)

Philadelphia chromosome, misregulation of tyrosine kinase, BCR-ABL fusion

5
New cards

t(14;18) disease

Follicular lymphoma

6
New cards

t(14;18)

Fusion of anti-apoptotic factor BCL-2 with immunoglobulin promoter, cell immortality

7
New cards

t(15;17) disease

APML

8
New cards

t(15;17)

Fusion of retinoic acid receptor with tumor suppressor PML (PML-RARα), treat with vitamin A derivative

9
New cards

t(11;14) disease

Mantle cell lymphoma

10
New cards

t(11;14)

Fusion of cyclin D1 with immunoglobulin promoter, cyclin overexpression promotes G1→S

11
New cards

APML markers

MPO+, TdT-, CD34-

12
New cards

ALL markers

CD34+, TdT+, CD19+, CD10+, CD3-, MPO-

13
New cards

Mantle cell lymphoma markers

CD5+, CD19+, CD20+, CD23-

14
New cards

SLL/CLL markers

CD5+, CD19, CD20+, CD23+

15
New cards

Hodgkin lymphoma markers

CD30+, CD15+, frequently EBV+, PD-L1, PD-L2

16
New cards

DLBCL markers (diffuse large B cell lymphoma)

CD19+, CD20+, BCL-6, BCL-2