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this originally was Calabria ch 7 but altered to fit my 101 class
what are the parts of the skeletal system?
bones, joints, cartilage, and ligaments
structural functions of bone
gives shape to things, support (ie: vertebrae), protection (like ribs protect organs), and movement (interact with muscles and move at joints, also stabilizes)
function of bone- blood cell formation
hematopoiesis (process of blood cell formation) occurs in bone marrow. bone marrow produces ALL types of blood cells and platelets. The marrow is a net-like mass of CT found within the bones
function of bone- yellow marrow
yellow marrow stores fat, inactive in blood cell produciton
inorganic salt storage: what does the extracellular matrix of the bone tissue include
collagen and inorganic mineral salts. 70% of the EC matrix is calcium phosphate
inorganic salt storage- what is calcium required for?
blood clot formation, nerve impulse conduction, and muscle contraction
inorganic salt storage- what happens when the blood is low on calcium?
the parathyroid hormone stimulates osteoclasts to break down bone tissue and release calcium from the EC and into the blood.
inorganic salt storage- what happens when the blood is high on calcium?
osteoclast activity is inhibited, and calcitonin stimulates osteoblasts to form bone tissue, storing/depositing excess calcium in the bone tissue
what kinds of tissues do bones contain?
bone tissue, cartilage, dense, CT, blood, and nervous
what r the 2 major subdivision of the skeleton
axial and appendicular
what does the appendicular skeleton include
bones of upper and lower limbs. ex: pectoral and pelvic gridle, bones of arms and legs
what does the axial skeleton include?
boney cartilage to protects and support the organs of the head, neck, and trunk. Exs: skull, vertebrae, ribs, and sternum
How are bones classified?
according to shape
long bones +examples
longer than they are wide. expanded/rounded ends. ex: femur, tibia, metacarpals
short bones + examples
same width and length- cube like. Examples: wrist bones (carpals) and ankle bones (tarsals)
sesamoid bones r a short bone that form with tendons (patella)
flat bones + examples
very thin and broad in shape, almost like a plate, a sandwich of compact bone with layer of spongy bone in between. protects underlying organs and muscle attachment. ex: sternum, ribs, scapula
Irregular Bones
+examples
unique shape, fits location. ex: skull, vertebrae, hip bones
what are the 2 basic types of bone (osseus) tissue
compact bone: smooth and homogenous
spongy bone: many open spaces
how can you define spongy bone?
as light, low density, flexible, and weak bone
what's other names for spongy bone?
trabeculae or cancellous
where is spongy bone found
on epiphysis of long bones, near joints, and inside vertebrae
describe the formation of spongy bone
the spongy bone itself is the bony rods/branches- the trabeculae. the osteocytes are within the trabeculae (which are within lacuna). unlike compact bone, the osteocytes do not get their nutrients from canals, instead their canaliculi branch to the surface of the trabeculae, which is where blood vessels are. between the lacunae is the lamella.

describe the formation of the trabeculae, why's it the way it is?
to bear mechanical stress. the cavities in between the spongy bone contain bone marrow.
osteoblasts
secrete bone matrix that consists of collagen and other proteins. responsible for bone growth. synthesizes bone and mineralizes it.
how do osteoblasts become osteocytes
once it's surrounded by enough of the matrix it produced, it has completed its job and turns into an osteocyte
osteocytes
mature bone cells that monitor and maintain bone matrix, communicating the info to other cells. remain in lacuna
osteoclasts
multinucleate cells that can break down bone with the help of enzymes.
lamellae
layers that are parallel inside trabeculae and compact bone that help with bone strength. kinda like layers of tree trunk rings
what are units of compact bone called
osteons
describe the lamellae within each osteon
made of collagen, each layer having a different direction of collagen opposite of the one next to it. the purpose of this is to resist torsion
middle of osteon
Haversion canal/central canal. contains blood vessels and nerve fibers that nourish the osteon (to get to the osteocytes, canaliculi branch to it through the lacuna)
Volkmann/perforating canal
run perpendicular to the Haversion canals. allows for connections to run all the way from the periosteum (outside) to central canals, to medullary cavity
where is compact bone usually found?
diaphysis. In 80% of skeleton, crucial for resisting stress. Also a layer around the epiphysis to protect the spongy bone
proximal epiphysis
closest point of attachment, closest to shoulder or hip joints. identifiable by that ball that sticks out, goes into the glenoid cavity
distal epiphysis
farthest from point of attachment
what is found at both epiphyses to articulate
articular cartilage, made of hyaline. this is to stop friction of bones rubbing together when they're connected
where is red bone marrow found (in relation to the long bone)
at the epiphysis, but also a small bit on the outside of the medullary cavity. it will be found in between the spaces of the trabeculae (spongy bone)
epiphyseal plate
where your bone will grow as it gets longer. made of hyaline cartilage.
-once fully grown, you can see the epiphyseal line, which is a remnant of the plate
yellow bone marrow
fills the medullary cavity within the diaphysis. stores fat and nutrients
medullary cavity
hollow space inside the diaphysis, but is filled with yellow bone marrow. contains red marrow until around 6/7
Periosteum
outer layer of bone material. it is a covering of dense CT, and helps repair the bone (bc osteoblasts line it)
perforating (Sharpey’s) fibers secure periosteum to underlying bone
endosteum
the inner layer, kinda lines the medullary cavity and is made of CT. if the compact bone needs to grow thicker, it deposits new bone material along the endosteum
ossification
process of bone formation
for this class, what is the way (long bone) grows and develops?
endochondral ossification
what are the 2 major phases of ossification in long bones
osteoblasts cover the cartilage model and form the bone matrix
the cartilage is covered by bone, and the cartilage starts to break down to eventually form the medullary cavity
endochondral ossification- or long bone formation in an embryo, fetus, and young child
1) hyaline cartilage model is made for future bones
2) as cartilage degenerate, a calcified periosteum form around the cartilage. blood is located on the sides, so that a bony collar can be made
3) (now fetus) blood penetrates into the empty spaces left by the degeneration of the chondrocytes. bones starts to get made on the inside. note that the blood carries osteoblasts and osteoclasts. you first start making bone in the diaphysis, around the area of where the medullary cavity will be.
4) blood penetrates into the epiphysis and creates spongy bone
5) note that as the child grows, the medullary cavity will cut using osteoclasts to make the middle bigger and grown appositionally using osteoblasts
5) the space between spongy bone compact bone of the diaphysis is the epiphyseal plate, and once the 2 meet, it all becomes bone
how do bones grow like upwards when a person is a child?
cartilage is constantly formed on the epiphyseal plate and on the articular cartilage
old cartilage constantly broken down and replaced by bony matrix
bone resorption
osteoclasts break down bone, take away calcium
bone deposition
osteoblasts form new bone
how is a bone remodeled and have appositional growth?
appositional growth: outwards bone growth
osteoblasts in periosteum add bone matrix to outside of diaphysis
osteoclasts inside, in endosteum remove bone from it
basically, just changes the proportions, just reshaping
what controls bone growth?
hormones
what are the 2 reasons why bone would ever need to be remodeled (breaking down or building up)
blood calcium level
break a bone
Vitamin D
necessary for absorption of calcium
how is the axial skeleton divided into 3 ways?
skull, vertebral column, and bony thorax
what are parasinuses and what do they do?
they’re hollow portions of bone around the nasal cavity that lighten the skull and amplify sound
what are examples of paranasal sinuses?
frontal, ethmoid, sphenoid, maxillary
primary curvatures
curve outwards, a c-shape. is the thoracic and sacrum and the shape is present at birth, like developed first
secondary curvatures
curves that are develop after birth, go inwards and point anteriorly. includes the cervical and lumbar region
bony thorax
is the thoracic cage, which is the sternum, ribs, and the thoracic vertebrae
what parts make up the appendicular skeleton?
limbs, pectoral girdle, and pelvic girdle
shoulder/pectoral girdle
composed of clavicle and scapula. very weak girdle
pelvic girdle
formed by 2 coxal (hip) bones, which formed by 3 pairs of fused bones: the ilium, ischium, and the pubis.
the girdle also includes the sacrum
what does the pelvis include?
same as pelvic girdle, but also includes the coccyx
what functions does the pelvic girdle have
holds weight of body
protects organs
arches of feet
the 2 longitudinal arches run front to back. medial and lateral
transverse arch goes across
bones usually form those arches, but if any of them are fallen it can result in flat feet
what do bones start out as?
-long bones r hyaline cartilage
-flat bones r fibrous membranes
growth of cranium and in relationship to body
growth related to brain growth
2 yrs: skull is ¾ size of adult skull
8 or 9: skull is near adult in size and proportion
6 through 11: face grows out from the skull
skeletal changes
at birth, head and trunk are proportionately longer than limbs
during puberty, the female pelvis broadens, while the male skeleton becomes robust
osteoporosis
loss of bone density, bones become very brittle. due to low intake of dietary calcium, lack of physical activity, and decrease of blood estrogen in females
affects mainly women, 50% of women over 65
still affects men, 20% over 70