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Carbohydrates
Provides energy, primary fuel source for the brain, nerve tissues, and red blood cells, promotes healthy gut function. DRI 130g/day, different than AMDR. Carbs are essential nutrients coming from the diet
Monosaccharides
Simple, glucose, fructose, galactose.
Disaccharides
2 monosaccharides together, maltose, sucrose, lactose
Maltose
Starch, glucose + glucose
Sucrose
table sugar, fructose + glucose
Lactose
Sugar in milk and yogurt, galactose + glucose
Lactose Intolerance
Insufficient production of lactose. 65-75% people lose ability to produce lactose, more than 1/3 of the US has this. Food sources can be milk and yogurt. Symptoms include nausea, pain, diarrhea, excessive gas.
High fructose corn syrup
Found in many processed products, inexpensive sweeteners or desserts and sodas. 55% fructose generally, the remainder is glucose. Hormonal response may be different, ghrelin (appetite stimulating hormone) not as suppressed by HFCS, meaning you don’t feel full when eating HFCS. Adverse effect on certain blood lipids (triglycerides) has been confirmed
Non-sugar sweeteners
Aspartame, stevia, sucralose (splenda). World helath organization reccomends against using them to control body weight or reduce risk of noncommunicable disease. Aspartame ‘limited evidence’ for cancer in humans, specifically liver cancer, acceptable level is 40mg/kg body weight. American heart association reccomends replacing sugary & diet drinks with plain, carbonated, or unsweetened water.
Starch
Complex, occasionally-branched glucose chains. Plants store glucose as this, which we then consume. Some easily digested (white flour); others take longer (beans) while some aren’t digested (resistant starch-technically a type of fiber)
Wheat bran
Protective coating
Wheat endosperm
Stores protein
Wheat germ
Grows in fat
Enriched
Adds things that woudl’ve been there if the whole grain was kept.
Glycogen
Doesn’t come from food, highly branched glucose chains (cellulose), body’s storage form of glucose, structure is ideal for rapid release of glucose
Dietary fiber
Cannot break down, an example is cellulose, long strands of glucose. Provides structure to plant cell walls, bonds can’t be broken. Large intestine feeds off this fiber. Reccomended fiber intake is 14 grams per 1000 kcal
Water insoluble fiber
Make up cell walls and tough structures of plants (skin, heavy portion). EX: cellulose, hemicellulose, and lignin. Seem to make development of certain types of cancer less likely. Improves digestive function. Resistant to fermentation > easier to use bathroom
Water soluble fiber
Viscous fibers that can make a gel, occur in various watery compartments of plant tissue. EX: pectins, gums, and mucilages (oat, barely, citrus fruit). Lower blood cholesterol
Strategies for increasing fiber
Choose high fiber cereals and breads, eat legumes, choose fruits and veggies with edible skins or seeds, add fiber gradually and maintain a high fluid intake
Benefits of fiber
Lowers cholesterol through soluble fibers such as fruits, veggies, oat bran, and legumes, it regulates blood glucose levels, encourages healthy bowel function through insoluble fibers which are the bulk of stool such as wheat bran, skins, and seeds, it also helps with weight management
Carbohydrate digestion
Beginning in the mouth, chewing and grinding is occuring and salivary amylase is breaking down starch. In the esophagus, peristalsis is occuring. In the stomach, gastric juices including hydrochloric acid which stops digestion. The stomach also is very acidic so it denatures proteins. The pyloric valve turns food into chyme. In the liver, delivered monosacharrides are converted into glucose when glucagon tells it to and then enters the circulatory system to be used. In the pancreas, enzymes are produced such as sucrase, maltase, lactase, amylase, insulin (glycogen) and glucagon. In the small intestine enzymes are working from the pancreas and in the large intestine insoluble fiber remains
Lipid digestion
In the mouth, lingual lipase is in babies only. In the stomach, fats are delaying gastric emptying which moves slower into the small intestine. In the liver, it is producing bile then giving it to the gallbladder to store along with the CCK hormone. The pancreas produces lipase to work on lipids.
Celiac disease
Not an allergy, but an autoimmune disease. Sensitivity to proteins (gluten) in wheat, rye, and barley. Consumption triggers an immune response and the small intestine villi and microvilli are damaged which affects the absorption of nutrients and causes bloating, gas, and diarrhea and long term consequences. Needs to be diagnosed by a health care professional. Individuals can consume quinoa, rice, soy, and corn but no oats due to cross contamination.
Small intestine digestion
Digestive enzymes from pancreas assist in digestion and absorption. Lactase, maltase, sucrase, and amylase digest starch, starch digests to disaccharides then enzymes split into monosaccharides. Monosaccharides delivered to liver and here, galactose and fructose are converted to glucose. From liver glucose enters the circulatory system to transport cells
Blood glucose regulation
Hormones from the pancreas help control it, insulin opens the door for glucose to enter and signals the body to uptake glucose. Glucagon is a pancreatic hormone that prevents blood sugar from dropping too low by signaling the liver to release stored glucose into the bloodstream (triggers the breakdown of liver glycogen)
Glycemic index (GI)
Ranks CHO foods on how quickly they enter bloodstream and elevate blood sugar. Based on 50 grams of CHO (food) and compared to score of standard food (glucose or white bread). High GI foods are quickly digested and the blood sugar response is fast and high. Low GI foods are slowly digested and blood sugar response is slow and steady. You should choose low GI foods if it is eaten alone, and high GI foods after exercise
Usefulness of fats
Fats in body: Energy stores (80% of energy), muscle fuel, padding (fat pads within bones, protection), insulation (warmth), emergency reserve (body feeds off fat when hungry). Fats in food: Nutrient, energy, transportation, sensory appeal, satiety, texture
Lipids AMDR
20-35%, 9kcal/g
Triglycerides
glycerol, food fat and body fat is stored fat. 3 Fatty acids: saturated, trans, and unsaturated. Unsaturated can be mono or poly. Most common lipid in foods, sources of fat in the US diet are fats and oils; red meats, poultry, fish, and dairy products. Body fat is composed mainly of these, and they consist of glycerol + 3 fatty acids.
Saturated fats
<10% RDA, Single bonds, the #1 food is sandwiches, then it can also come from tropical oils like coconut or palm, and dessert foods due to high levels of butter. Animal products can be saturated if they are full fat dairy like whole milk, cheese, butter, or ice cream. A diet too high in sat. fat can lead to high LDL levels.
Trans fat
Produced by making liquid fats more solid and makes the product more shelf stable (hydrogenating unsaturated fats). Increases LDL cholesterol.
Unsaturated
Can be mono or poly, mono is one degree of unsaturation and poly is multiple degrees of unsaturation
Monounsaturated fats
1 double bond, oleic acid in olive, avocado, peanut, and canola oil. Hydrogens are missing which causes a point of unsaturation.
Polyunsaturated fats
Multiple double bonds, Omega-3 (alpha linolenic) > essential, DHA, EPA. Can come from oils like flaxeed, walnut or canola oil. Omega 3 can come from fatty fishes like salmon, sardines, and tuna. Omega 6 (linoleic) > essential, coming from vegetable oils. DRI established the omegas to possibly reduce total cholesterol
Phospholipids
emulsifiers. EX: lectin in eggs helps oil and water stay together in mayo. glycerol + 2 fatty acids
Sterols (cholesterol)
This produces the cholesterol needed. In food, it can be found in animal products (the actual flesh and what comes from them) and in the body can be found as vitamin D, testosterone, and bile.
Lipoproteins
Endogenous or exogenerous
Endogenous lipoproteins
Inside the body (liver). VLDL or HDL proteins.
Exogenerous lipoproteins
Outside body, comes from diet, goes through small intestine, then into chylomicron and then into the lymphatic system.
VLDL lipoprotein
Endogenous, primarily triglycerides. LDL is “bad cholesterol'“, so the lower level the better. Can be accumulated in circulation and cause problems like clogged arteries (saturated fat). Half triglyceride: carry TG from liver to body tissues and shrink after triglycerides removed and eventually gather cholesterol to form LDL
HDL protein
Remaining cholesterol from cells > liver. High protein content compared to LDL and VDL. Physical activity impacts this and the higher the amount of this the better. Transport cholesterol back to the liver from peripheral cells which reduces buildup of cholesterol.
chylomicrons
Transport lipids from intestinal cells to the liver and other tissues. Highest fat content.
LDL protein
Found in something like blood, bad cholesterol. Derived from VLDLs as cells removed TG from them. Circulate through the body making their contents available to cells of all tissues.
How to limit saturated fats
Choose meats that are loin or round cuts, and prepare them by baking or grilling. Choose low fat dairy products such as 1% or skim milk, reduced fat or low fat cheeses, and avoid tropical oils commonly found in processed foods (coconut, palm, palm kennel)
Protein digestion
Hydrochloric acid denatures proteins in the stomach, and the proteins become strands of amino acids that break down further. In the small intestine, amino acids are absorbed. The enzymes split peptide strands into tripeptides and dipeptides and the enzymes on the surface of the small intestine further break down di and tripeptides into amino acids which are then absorbed into the bloodstream
Amino acids
Building blocks of proteins, containn nitrogen. Each amino acid has a backbone made of an amine group and an acid group, then a side chain.
Nonessential amino acids
Body produces these amino acids
Conditionally essential amino acids
Obtain from diet if insufficient amount produced
Essential amino acids
Body cannot produce them, omega 3 and omega 6
Structure of amino acids
Same basic structure, central carbon with an amino group and an acid group, side group differs from one amino acid to the next. Chains are amino acids linked together, and they form a strand of amino acids, which is part of a protein. There is only one correct sequence of amino acids for each kind of protein, and that is determined by genetics.
Step 1 of building proteins
The first shape of a strand of amino acids is a chain, which can be very long.
Step 2 of building proteins
coiling the strand. The strand of amino acids takes on a springlike shape as the side chains variously attract and repel each other
Step 3 of building proteins
Folding the coil. The coil then folds and flops over on itself to take a functional shape
Step 4 of building proteins
Once coiled and folded, the protein may be functional as is, or it may need to join with other proteins or to add a carbohydrate molecule or a vitamin or mineral, as the iron of the protein hemoglobin demonstrates
Complete protein
High quality proteins. Animal foods such as eggs, milk, meat and also includes soy. These contain all of the essential amino acids (9).
Incomplete protein
Plant foods such as corn
Complementary proteins
Combining two incomplete proteins. EX: legumes and grains
How much protein?
AMDR: 10-35% total calories
RDA: .8g per kg body weight (gxkg) kg=lb/2.2
Dietary guidelines: 1.2-1.6g/kg/day
Some individuals may require more than RDA. More protein alone doesn’t build more muscle. Populations: pregnancy, infants/children, older adults (avoid sarcopenia)
nitrogen balance
Positive: Intake > excretion (times of growth like pregnancy and childhood)
Negative: Excretion > intake (sick)
Equilibrium: intake = excretion (healthy)
Where protein comes from
Protein: 1 ounce of meat, 1 egg, ½ cup beans = 7g of protein
Dairy: 1 cup milk/yogurt, 1 ounce cheese = 8g protein
Grains: ½ cup cooked= 3 ish g of protein
Protein functions
Energy: protein can be used for energy and glucose. Blood clotting, the structure is a component of many body tissues, acid-base and fluid & electrolyte balance: act as buffers or maintain body fluids, hormones: messenger molecules, insulin is a protein. Transportation: carry nutrients, Enzymes: build up and break down all the compounds the body makes and uses- acts as a catalyst, Antibodies: giant proteins formed in response to body invaders
Protein metabolism (feasting)
Cannot store protein as is > excrete amino group > use to make glucose for storage as glycogen or fat for energy
protein metabolism (fasting)
Deplete glycogen stores > draw on triglycerides > draw on proteins from blood then muscles
How much carbohydrate?
AMDR: 45-65% total kcals
RDA: 130g
DRI: grams fiber: 14g per 1000 kcal
Dietary guidelines: added sugar limit: 10g or less/meal
AHA: <6% total kcals
How much fat?
AMDR: 20-35%
Dietary guidelines: saturated fat limit: <10% total kcals
AI for 2 fatty acids: alpha linolenic acid and linoleic acid
Metabolism
How the body obtains and uses energy from food
Anabolic/Anabolism reactions
Requires energy, build up: building of proteins from amino acids.
catabolism
Releases energy, Break down: break down of protein into amino acids
Enzymes
Catalysts of metabolic reactions. EX: lactase, lipase, amylase
Coenzymes
Organic, associate with enzymes, without coenzyme, an enzyme cannot function
Feasting metabolism
Metabolism favors fat formation, regardless whether excess kcal from protein, fat, or carbohydrates. Dietary fat to body fat is most direct and efficient conversion. Carbohydrate and protein have other roles to fufill before conversion to body fat/
Transition from feasting to fasting
Glucose, glycerol, and fatty acids are used then stored. Fasting state draws on these stores: glycogen first then fat are released, preventing ketosis because it is expensive and protein sparing is important. Fasting is in between meals or overnight, starving is more chronic
Factors influencing metabolic rate
age, body composition, height, growth, fever, physiological stress, environmental twmperature, thyroxine (hormone), Fasting/starving/malnutrition (role of popular diets)
Low carb diet
lowers insulin levels (carbs>glucose> glycogen> insulin production), burns stored fat for energy, typically < AMDR for carbs, South beach was a popular low carb diet, Short term: weight loss Long term: low CHO versus other diets = no difference in weight loss in a year
Low carb diet pros and cons
Pros: Short term weight loss, may reduce intake of refined carbohydrates, studies have shown reduction in triglyceride levels.
Cons: May lead to increased saturated fat intake > LDL levels rise leading to heart problems. May also lead to decreased fiber intake
Ketogenic diet
Severe carbohydrate restriction that induces ketosis, high fat (usually saturated fat) intake, moderate protein intake (Atkins is a popular keto diet). Forces the body to switch from using glucose to using fats, The body is in a state of ketosis (producing ketone bodies) due to glycogen depletion. Used to be used to treat epilepsy because the brain converts carbs into glucose which the brain prefers
Ketogenic diet pros and cons
Pros: Sezuire reduction, short term weight loss, water loss from loss of glycogen stores
Cons: constipation (not enough fiber), muscle cramps (water loss), weakness (drawing too much from protein stores), difficulty concentrating (glucose) , rashes, bad breath (ketone bodies), increased risk of kidney stones, increased LDL cholesterol (saturated fat), nutrient deficiencies (carb is primary source of vitamins and minerals), poor bone health, studies have shown loss in muscle mass on this diet
Dietfits
12 month healthy low fat vs healthy low carb diet. Both groups instructed to: maximize vegetable intake, minimize intake of refined fibers, added sugars, and trans fats, focus on whole foods that were minimally processed, nutrient dense, and prepared at home whenever possible. Results: no difference in mean weight loss between groups. LDL increased in healthy low carb group, triglyceride decreased less in healthy low fat group.