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Active Immunity
Immunity produced by the body's own immune response following exposure to an antigen or vaccine
Adaptive Immunity
Targeted immune response that develops over time and creates long-lasting immune memory
Adjuvant
An ingredient added to a vaccine to boost the immune response
Adverse Event
Any unexpected or harmful medical occurrence following vaccination
Alcohol Swab
An alcohol-soaked pad used to clean the skin before an injection to prevent infection
Anaphylaxis
A severe, potentially life-threatening allergic reaction
Antibody
A protein produced by the immune system to neutralize specific pathogens
Antigen
A substance that triggers an immune response
B Cell
A type of white blood cell that produces antibodies
Bevel
The slanted opening at the tip of a needle
Booster Dose
An extra dose of a vaccine given to maintain or restore immunity over time
CAIR (California Immunization Registry)
A confidential database tracking vaccine doses administered in California
Coadministration
Giving two or more vaccines during the same clinical visit
Cold Chain
The temperature-controlled supply chain required to safely store and transport vaccines
Conjugate Vaccine
A vaccine combining a weak antigen with a strong carrier protein to improve immune response
Contraindication
A condition or factor that makes receiving a vaccine unsafe
Diluent
A liquid used to reconstitute a powdered vaccine
EUA (Emergency Use Authorization)
FDA authorization permitting unapproved medical products during a public health emergency
Immunity
The body's ability to resist a specific disease or pathogen
Immunization Schedule
Recommended timeline for administering vaccines based on age or health risk
Immunoglobulin (Ig)
Antibodies present in blood plasma used to provide immediate, short-term passive protection
Inactivated Vaccine
A vaccine containing a killed version of the disease-causing pathogen
Injection Sites
Specific anatomical locations where injections are administered
Innate Immunity
The body's non-specific, immediate first line of defense against pathogens
Intradermal (ID)
An injection given directly into the dermis
Intramuscular (IM)
An injection given deep into muscle tissue
Intranasal (IN)
A needle-free medication or vaccine delivered into the nasal cavity
Live Attenuated Vaccine
A vaccine containing a weakened form of a live pathogen
Memory Cell
Long-lived immune cells that recognize past antigens to trigger a rapid response upon re-exposure
Minimum Intervals/Ages
The shortest allowed timeframe between vaccine doses or youngest age for administration
mRNA Vaccine
A vaccine using genetic material to instruct cells to build a viral protein that triggers immunity
Needle Gauge
Standard measurement of needle thickness where larger numbers mean thinner needles
Passive Immunity
Temporary protection provided by receiving antibodies from an outside source
Polysaccharide Vaccine
A vaccine made from long chains of sugar molecules found on certain bacteria outer coats
Precaution (Vaccines)
A condition that increases risk of an adverse event or compromises vaccine efficacy
Recombinant Vaccine
A vaccine created using genetic engineering to insert pathogen DNA into another cell
Reconstitution
Mixing a dried or powdered vaccine with a liquid diluent prior to administration
Seroconversion
The development of detectable specific antibodies in serum after vaccination or infection
Serology / Titer
A blood test measuring antibody levels to check for immunity
Sharps Container
A puncture-resistant box used for safe disposal of needles and medical sharps
Subcutaneous (SC)
An injection given into the fatty layer of tissue just under the skin
Subunit Vaccine
A vaccine containing only specific isolated fragments of a pathogen rather than the whole germ
T Cell
A white blood cell involved in cell-mediated immunity and destroying infected cells
Toxoid Vaccine
A vaccine made using an inactivated toxin produced by a pathogen
Vaccination
The act of introducing a vaccine into the body to produce immunity to a specific disease
Vaccine
A biological preparation that stimulates immunity against a specific pathogen
VAERS (Vaccine Adverse Event Reporting System)
A national safety monitoring system for reporting post-vaccination adverse events
Vector Vaccine
A vaccine that uses a modified harmless virus to deliver genetic code for an antigen
VIS (Vaccine Information Statement)
An educational document detailing benefits and risks given to vaccine recipients
VSD / VFC
Vaccine Safety Datalink / Vaccines for Children assistance program
Acute Pain
Sharp, sudden-onset pain usually caused by tissue injury that resolves as healing occurs
Afebrile
Having no fever
Analgesia
Relief from pain without loss of consciousness
Analgesic
A medication used to relieve pain
Antipyretic
A medication used to reduce fever
Arthralgia
Joint pain
Aura
Sensory disturbances preceding a headache or seizure
Cephalalgia
Medical term for a headache
Chronic Pain
Persistent or recurrent pain lasting longer than 3 to 6 months
Cluster Headache
Severe, unilateral, recurring headaches often centered around one eye
Febrile
Characterized by or showing symptoms of a fever
Fever / Pyrexia
An elevation in body temperature above normal baseline
Migraine
A throbbing, often unilateral headache frequently accompanied by nausea and light sensitivity
Myalgia
Muscle pain or soreness
Neuropathic Pain
Pain caused by damage or disease affecting the nervous system
Nociceptive Pain
Pain resulting from tissue damage detected by intact pain receptors
Nociceptor
A specialized nerve receptor that detects painful or tissue-damaging stimuli
NSAID
Nonsteroidal Anti-inflammatory Drug that reduces pain, fever, and inflammation
Pain
An unpleasant sensory and emotional experience associated with actual or potential tissue damage
Paresthesia
An abnormal skin sensation like tingling or prickling
Photophobia
Extreme sensitivity to or discomfort from light
Somatic Pain
Pain originating from skin, muscles, bones, joints, or connective tissue
Status Migrainosus
A severe, debilitating migraine attack lasting longer than 72 hours
Tension Headache
A common, dull, aching headache often felt like a tight band around the head
Thermoregulation
The body's process of maintaining an internal temperature within a normal range
Visceral Pain
Pain originating from internal organs within the chest, abdomen, or pelvis
Abdomen
The region of the body between the chest and pelvis containing stomach, intestines, and liver
Anorectal
Pertaining to the anus and rectum
Antacid
A medication that neutralizes stomach acid for quick relief from heartburn
Antiemetic
A medication used to prevent or relieve nausea and vomiting
Barrett Esophagus
Precancerous changes in the lower esophageal lining caused by chronic acid reflux
Borborygmi
Rumbling or gurgling noises caused by fluid and gas moving through the intestines
Bowel Movement (BM)
The discharge of waste matter from the large intestine through the anus
Bristol Stool Form Scale
A diagnostic tool classifying human feces into seven categories based on shape and consistency
Cathartic
A strong substance that accelerates defecation or bowel evacuation
CINV
Chemotherapy-Induced Nausea and Vomiting
Clostridium difficile
A bacterium causing severe diarrhea and colitis, often following antibiotic use
Colitis
Inflammation of the inner lining of the colon
Colostomy
A surgical opening connecting the colon to the abdominal surface to divert waste
Constipation
Infrequent, difficult, or painful passage of hard stools
Diarrhea
Unusually frequent, loose, or watery bowel movements
Dyspepsia
Indigestion marked by upper abdominal fullness, pain, or discomfort
Dysphagia
Difficulty or pain when swallowing
Enema
Fluid injected into the rectum to stimulate bowel evacuation or deliver medication
Emesis
The act of vomiting
Endoscopy
Procedure using a flexible scope with a camera to visually examine the GI tract interior
Esophagus
The muscular tube connecting the throat to the stomach
Esophagitis
Inflammation or irritation of the esophageal lining
Fecal Impaction
A large, hard mass of immobile stool trapped in the rectum or colon
Fiber Supplement
Dietary additive used to add bulk to stool and improve bowel regularity