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Systemic Circuit
Carries blood to and from gas exchange surfaces of the body.
Systemic Circuit Function
Carries oxygenated blood from heart to all tissues except lungs and returns deoxygenated blood carrying waste products, such as carbon dioxide, back to heart.
Oxygen-Rich Blood Ejection
Ejected under high pressure out of left ventricle (hearts main pumping chamber) through aorta (largest artery)
Smaller Arteries Origin
Branch off from the aorta to various parts of the body.
Arterioles Formation
Smaller arteries branch out into even smaller arteries known as arterioles.
Capillaries Formation and Pressure
Arterioles become progressively smaller, eventually forming capillaries where blood pressure is greatly reduced.
Pulmonary Circuit Definition
Carries blood to and from the gas exchange surfaces of the lungs.
Return of Deoxygenated Blood
Travels from organs and tissues from right atrium to right ventricle.
Pathway to Lungs
Deoxygenated blood is pushed through the pulmonary artery to the lung.
Pulmonary Artery Division
Divides forming the pulmonary capillary region.
Alveoli Gas Exchange
Microscopic vessels pass adjacent to alveoli (air sacs) where gases are exchanged across thin membrane.
Gas Exchange Mechanics
Oxygen crosses membrane into blood while carbon dioxide leaves blood through same membrane.
Newly Oxygenated Blood Flow
Flows into pulmonary veins and is collected by left atrium of the heart (collecting pool for Left ventricle)
Completion of Circulatory Loop
Contraction of left ventricle sends blood into the aorta.
Three Types of Blood Vessels
Arteries, veins, and capillaries.
Arteries Function
Carry blood away from the heart.
Veins Function
Carry blood to the heart.
Capillaries Location
Form networks between arteries and veins.
Exchange Vessels
Alternative name for capillaries; exchange materials between blood and tissues.
Capillary Exchanged Materials
Dissolved gases, nutrients, and wastes.
Heart Chambers Count
4 chambers total: 2 for each circuit (left and right - ventricles and atria).
Left Atrium Function
Collects blood from the pulmonary circuit.
Left Ventricle Function
Pumps blood to the systemic circuit.
Right Atrium Function
Collects blood from the systemic circuit.
Right Ventricle Function
Pumps blood to the pulmonary circuit.
Heart Location
Located directly behind the sternum.
Base of the Heart
Location of great veins and arteries.
Apex of the Heart
The pointed tip of the heart.
Thoracic Cavity Relation
Surrounded by pericardial sac and located between 2 pleural cavities.
Mediastinum Definition
Central tissue mass that divides the thoracic cavity into 2 pleural cavities.
Pericardium Definition
Double lining of the pericardial cavity.
Parietal Pericardium
Outer layer that forms the inner layer of the pericardial sac.
Visceral Pericardium
Inner layer of the pericardium, also known as the epicardium.
Structures of Pericardium
Pericardial cavity and pericardial sac.
Pericardial Cavity Location
Located between parietal and visceral layers; contains pericardial fluid.
Pericardial Fluid Function
Acts as a lubricant to reduce friction between heartbeats.
Pericardial Sac Composition
Made of fibrous tissue containing collagen; surrounds and stabilizes the heart.
Pericarditis Definition
An infection of the pericardium.
Pericarditis Signs
Scratching sound heard due to rubbing of surfaces and fluid collecting around heart.
Atria Structure
2 thin-walled chambers with expandable outer auricles.
Sulci Coronary Sulcus
Divides the atria and ventricles.
Interventricular Sulci
Anterior and posterior sulci separate left and right ventricles and contain blood vessels of cardiac muscle.
Layers of the Heart Wall
Epicardium, myocardium, and endocardium.
Epicardium
The outer layer of the heart wall.
Myocardium
The middle layer of the heart wall.
Endocardium
The inner layer of the heart wall.
Epicardium Characteristics
Visceral pericardium, covers the heart, serous membrane, exposed mesothelium, areolar connective tissue.
Myocardium Characteristics
Muscular wall of the heart forming atria and ventricles; contains concentric cardiac muscle tissue, blood vessels, and nerves.
Atrial Myocardium
Wraps around great vessels like the pulmonary artery and aorta.
how many ventricular myocardium divisions are there?
2
Superficial Ventricular Muscles
Muscles that surround the ventricles.
Deep Ventricular Muscles
Muscles that spiral around and between the ventricles.
Intercalated Discs
Structures that interconnect cardiac muscle cells.
Desmosomes in Intercalated Discs
Secure cardiac muscle cells together.
Gap Junctions in Intercalated Discs
Link cardiac muscle cells to convey force of contraction and propagate action potentials.
Cardiac Muscle Cell Characteristics
Small size, single central nucleus, branching interconnections, and intercalated discs.
septa/ Interatrial Septum
Separates the left and right atria.
Interventricular Septum
Separates the left and right ventricles.
Vena Cava Function
Delivers systemic circulation to the right atrium.
Superior Vena Cava Receives blood From
Head, neck, upper limbs, and chest.
Inferior Vena Cava Receives blood From
Trunk, viscera, and lower limbs.
Coronary Sinus Function
Cardiac veins return blood to coronary sinus; coronary sinusopens into the right atrium.
Foramen Ovale Definition
An opening through the interatrial septum before birth that connects the two atria.
Fossa Ovalis
Formed when the foramen ovale seals off at birth.
Pectinate Muscles
Contain prominent muscular ridges on anterior atrial wall and inner surfaces of right auricle.
Valve Cusps
Fibrous flaps that form bicuspid (2) and tricuspid (3) valves.
Free Edges of Cusps
Attach to chordae tendineae from papillary muscles of the ventricle.
Valve Cusp Prevention
Cusps prevent valves from opening backward.
Right Atrioventricular (AV) Valve / Tricuspid Valve
Opening from right atrium to right ventricle with 3 cusps; prevents backflow.
Trabeculae Carneae
Muscular ridges on the internal surface of the right ventricle.
Moderator Band
Ridge in right ventricle containing part of conducting system that coordinates cardiac muscle cell contractions.
Right vs Left Ventricle Wall
Right ventricle wall is thinner and develops less pressure than the left ventricle.
Right vs Left Ventricle Shape
Right ventricle is pouch-shaped while the left ventricle is round.
Atrioventricular (AV) Valves Location
Located between atria and ventricles; one-way valves prevent backflow during contraction.
Blood Pressure on AV Valves
Closes valve cusps during ventricular contraction.
Papillary Muscles Function
Tense chordae tendineae to prevent valves from swinging into atria.
Semilunar Valves Function
Pulmonary and aortic tricuspid valves prevent backflow from pulmonary trunk and aorta into ventricles.
Semilunar Valves Structure
Have no muscular support; 3 cusps support like a tripod.
Aortic Sinuses Location
Located at the base of the ascending aorta.
Aortic Sinuses Functions
Prevent valve cusps from sticking to aorta and serve as origin of right and left coronary arteries.
Carditis Definition
An inflammation of the heart that can result in valvular heart disease (VHD). can cause rheumatic fever
Rheumatic Fever Cause
Develops after a streptococcal infection.
Rheumatic Fever Symptoms
High fever, joint pain, and rash.
Rheumatic Fever Cardiac Impact
50-60% develop carditis and scar tissue in myocardium and heart valves.
Rheumatic Fever Latency
May not appear for 10-20 years.
Rheumatic Fever Valve Changes
Valves become thick and calcified, though blood flow is not totally blocked.
Rheumatic Fever Infection Risk
Heart is more susceptible to bacterial infections causing endocarditis (hence antibiotics from dentist).
Coronary Circulation Components
Coronary arteries and cardiac veins supplying blood to heart muscle tissue.
Coronary Arteries Origin
Left and right arteries originate at aortic sinuses.
Coronary Arteries Blood Flow
Driven by high pressure and elastic rebound forcing blood between contractions.
Right Coronary Artery Supplies
Right atrium, portions of both ventricles, cells of sinoatrial SA and atrioventricular AV nodes, marginal arteries (surface of right ventricle) , and posterior interventricular artery.
Marginal Arteries Location
On the surface of the right ventricle.
Left Coronary Artery Supplies blood to
Left ventricle, left atrium, and interventricular septum.
Branches of Left Coronary Artery (2 main branches)
Circumflex artery and anterior interventricular artery.
Cardiac Veins List
Great cardiac vein, anterior cardiac vein, posterior, middle, and small cardiac veins.
Great Cardiac Vein Function
Drains blood from area of anterior interventricular artery into coronary sinus.
Anterior Cardiac Vein Function
Empties directly into the right atrium.
Posterior, Middle, and Small Cardiac Veins
Empty into the great cardiac vein or coronary sinus.
The Heartbeat Definition
A single contraction of the heart.
Heart Contraction Sequence
The entire heart contracts in series: first the atria, then the ventricles.