TOP 300 Indication ILE 6

Amlodipine(Norvasc)

HTN, Chronic stable angina, Vasospastic angina

Atenolol(Tenormin)

cardioselective β adrenergic 🚫 Angina pectoris, HTN, AMI

Atorvastatin(Lipitor)

Primary/2ndary ASCVD prevention, Familial hypercholesterolemia

benazepril(Lotensin)

diabetic nephropathy, HF, kidney disease

Bisoprolol(Zebeta)

cardioselective β adrenergic 🚫 Angina, A-fib, HF, Ventricular arrhythmia

Canagliflozin(Invokana)

Atherosclerotic heart disease, diabetic kidney disease

candesartan(Atacand)

HF, HTN

Chlorthalidone(Thalitone)

HTN, Calcium nephrolithiasis

Clonidine(Catapres)

ADHD, refractory HTN

Dapagliflozin(Farxiga)

HrEF

Diltiazem(Cardizem)

HTN, stable chronic vasospastic angina

Doxazosin(Cardura)

α1 adrenergic 🚫 Benign postatic hyperplasia, HTN

Dulaglutide(Trulicity)

T2DM

Empagliflozin(Jardiance)

T2DM, CKD, HF

Enalapril(Vasotec)

AMI, kidney disease with proteinuria

Esomeprazole(Nexium)

H. pylori GI infection, erosive esophagitis, NSAID induced gastropathy

Ezetimibe(Zetia)

cholesterol absorption 🚫 Familial hypercholesterolemia, mixed hyperlipidemia, primary hypercholesterolemia, homozygous familial sitosterolemia

famotidine(pepcid)

GERD, indigestion, heartburn

Furosemide(Lasix)

edema related to HF

Gemfibrozil(lopid)

fibric acid coronary arteriosclerosis, familial type V hyperlipoproteinemia-Fridrickson Type 4hyperlipoproteinemia

Glimepiride(Amaryl)/Glyburide(Glynase)

2nd gen SU T2DM

Hydralazine(apresoline)

Peripheral vasodilator HTN

Irbesartan(Avapro)

T2DM Diabetic nephropathy, HTN

Labetalol(Normodyne)

αβ adrenergic 🚫 HTN

Lansoprazole(Prevacid)

duodenal ulder disease, gastric ulcer disease, H. pylori GI tract infection triple therapy, erosive esophagitis, zollinger-ellison syndrome

Lisinopril(Zestril)

ST segment elevation MI, HFrEF, HTN

Losartan(Cozaar)

HTN, CV accident reduction in HTN w left ventricular hypertrophy, diabetic nephropathy

Lovastatin(Altoprev)

coronary arteriosclerosis, familial hypercholesterolemia

Lubiprostone(Amitiza)

Cl channel activator Chronic idiopathic constipation, IBS-C, OIC

Liniaclotide(Linzess)

guanylate cyclase agonist Chronic idiopathic constipation, IBC-C, Functional constipation

Metformin(Glucophage)/Pioglitazone(Actos)/

Saxagliptin(Onglyza)/

Sitagliptin(Januvia)

T2DM

Metoprolol(Lopressor)

cardioselective β adrenergic 🚫 Angina, HFrEF, HTN, AMI

Nebivolol(Bystolic)/Olemsartan(Benicar)

cardioselective β1 selective adrenergic 🚫 HTN

Omeprazole(Prilosec)

GERD, Peptic ulder disease, H.pylori eradication, zollinger-ellison syndrome

Pantoprazole(Protonix)

H. pylori GI tract infection, duodenal ulcer disease

PEG(Miralax)

hyperosmotic laxative colonoscopy, barium enema prep, constipation

Propranolol(Inderal)

nonselective β adrenergic 🚫 Angina pectoris, cardiac dysrhythmia, HTN, prophylaxis migraine

Rifaximin(Xifaxan)

Hepatic encephalopathy, IBC without constipation, Travele’s diarrhea

Rosuvastatin(Crestor)

Hyperlipidemia, CV prevention, familial hypercholesterolemia

Semaglutide(Ozempic)

T2DM, weight

Simvastatin(zocor)

Hyperlipidemia, Primary/2ndary ASCVD prevention, CV 2ndary prevention, familial hypercholsterolemia

Spironolactone(Aldactone)

HF, Primary aldosteronism, HTN, Liver cirrhosis ascites

Torsemide(Demadex)

HF edema, renal failure, cirrhosis, HTN

Valsartan(Diovan)

HF, HTN, Acute coronary syndrome