IMB review section 7

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6 Terms

1
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What is the HSV gene cascade?

VP16 turns on alpha regulators which lead to beta enzymes, then gamma structural glycoproteins. VHS shuts off host protein synthesis

2
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What type of diseases are caused by HSV1?

oral-facial disease

3
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What type of diseases are caused by HSV2?

genital herpes

4
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Where does HSV1 like to spend its latency time?

trigeminal ganglion of sensory neurons

5
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Where does HSV2 like to spend its latency time?

sacral ganglia or the sensory neurons

6
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