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skin, hair, nails, glands
structures a part of integument
Protection against UV light, water loss, and microorganisms
Sensation receptors for temperature, touch, pressure, pain
Temperature regulation
Vitamin D production
Excretion of small amounts of waste
Funtions of integumentary system
Epidermis
Superficial layer of epithelial tissue
Dermis
Deep layer of connective tissue
Subcutaneous tissue
NOT part of skin
Loose connective tissue that connects skin to underlying structures
Epidermis
Dermis
parts of skin?
Epidermal Strata
Stratum basale
Stratum spinosum
Stratum granulosm
Stratum lucidum
Stratum corneum
Stratum basale
deepest portion of epidemis and single layer.
High miotic activity and cells become keratinized
stratum spinosum
Limited cell division, contain desmosomes, lamellar bodies, and additional keratin fibers
stratum granulosum
contains keratohyalin
in superficial layers, nucleus and other organelles degenerate and cell dies
stratum lucidum
thin, clear zone
found only in palms and soles
stratum corneum
most superficial and consists of cornified cells
thick skin
has 5 epithelial strata
found in areas subject to pressure or friction (palms of hands, fingertips, soles of feet)
fingerprints and footprints
thin skin
composed of 4 strata (no stratum lucidum)
more flexible than thick skin
covers rest of body
hair grows here
callus
increase in number of layers in stratum corneum
when this occurs over a bony prominence a corn forms.
cyanosis
blue color caused by decrease in blood oxygen content
erythema
red color caused by increased blood flow
dermis contains
contains nerves, blood vessels, hair follicles, smooth muscles, glands, and lymphatic vessels.
dermis function
sensory functions:
pain, itch, tickle, temperature, touch, pressure, two-point discrimination
subcutaneous tissue/hypodermis
deep to skin
contains: fibroblasts, adipose cells (1/2 of body’s adipose tissue), machrophages
subcutaneous tissue function
energy source
insulation
padding
arrector pili
type of smooth muscle
skin pushed up by movement of hair follicle
muscle contraction causes “hair to stand up”
sebaceous glands
holocrine (death of secretory cells)
oily secretion
prevents drying
apocrine
eccrine (merocrine)
two types of sweat glands
eccrine (merocrine) glands
most common
produce isotonic fluid (sweat) containing mostly water and some wastes.
numerous in palms and soles
appocrine glands
active at puberty
found in axillae, genitalia (external labia, scrotum), around anus.
ceruminous glands
modified merocrine sweat glands, external auditory meatus
cerumen (earwax)
in combonation with hairs, prevents dirt and insexts from entry and keeps eardrum supple
mammary glands
modified apocrine sweat glads that produce milk
stratum corneum
nail body
burns are measured in?
partial thickness: first degree (epidermis), second degree (epidermis and dermis)
full thickness: third degree (epidermis, dermis and subcutaneous tissue)
fourth degree affects deeper structures
skeletal system functions
support
protection
movement
storage
blood cell production
osteomalacia
if mineral removed bone bendy
osteoporosis
if collagen removed bone very brittle
mesenchyme stem cells
osteochondral progenitor (original) cells become chondroblasts or osteoblasts
trabeculae
interconnecting rods of plates of bone (scaffolding)
trabeculae contain
spaces filled with marrow
covered with endosteum
oriented along stress lines
central or haversian canals
parallel to long axis
contain blood vessels
lamellae
concentric, circumferential, interstitial.
osteon or haversian system
central canal, contents, associated concentric lamellae and osteocytes.
perforating or volkmanns canal
perpendicular to long axis.
contain blood vessels
direct flow of nutrients from vessels through cell processes of osteoblasts and from one cell to the next.
perforating canals
deliver blood to central canals
run perpendicular to length of the bone
diaphysis
shaft primarily made of compact bone
epiphysis
end of bone primatily made of spongy bone
epiphyseal plate: growth
hyaline cartilage; present until growth stops
epiphyseal line
bone stops growing in length
medullary cavity (child)
in children medullary cavity is red marrow
medullary cavity (adult)
in adults, red marrow is replaced by yellow in limb bones (except for proximal epiphyses of arm and thigh bones). Elsewhere, varying proportions of yellow/red marrows are found
periosteum
outer fibrous
inner is single layer of bone cells including osteoblasts, osteoclasts, and osteochondral progenitor cells
fibers of tendon become continuous with fibers of periosteum
Sharpey’s fibers
some periosteal fibers penetrate through the periosteum and into the bone. this strengthens the attachment of tendon to bone.
endosteum
similiar to periosteum, but more cellular. Lines all internal spaces including spaces in spongy bone.
Flat bones
no diaphyses, epiphyses
sandwhich of spongy
short and irregular bones
no diaphyses and not elongated
some flat and irregular bones of skull have sinuses lined by mucous membranes
sinuses lined by mucous membranes
Intramembranous ossification
takes place in connective tissue membrane
endochondral ossification
takes place in cartilage
Intramembranous ossification
bone development
which type of ossification forms skull bones, parts of mandible, diaphyses of clavicles?
what are fontanels?
Large membrance-covered spaces between developing skull bones; unossified.
what occurs at the epiphyseal plate?
bone grows in length organized into 5 zones
interstitial cartilage growth
when bone grows in length in anatomy terms is?
When bone grows in diameter
Appositional growth on the surface of the cartilage.
what happens to the epiphyseal plate when bone growth finishes?
It ossifies and becomes the epiphyseal line, stopping further height growth.
At what age range does the closure of the epiphyseal plate typically occur?
Between 12 and 25 years of age.
What can affect bone growth?
vitamin D levels
rickets:lack of vitamin D during childhood
Vitamin C levels
osteomalacia is the lack of what during adulthood?
lack of vitamin D leading to softening of bones.
Scurvy
Defiency of vitamin C
How does a lack of vitamin c affect the body?
wounds heal slower and teeth can fall out
Where does Growth Hormone come from, and what is its main job?
Origin The anterior pituitary gland (at the base of the brain).
Job: It acts as the body's "Build More!" signal to make you grow bigger and taller.
What is interstitial cartilage growth?
growth in length
What is appositional bone growth?
growth on the surface of cartilage (growth in diameter)
what hormone is required for growth of all tissues?
Thyroid hormone is requires for growth of all tissues.
What do reproductive hormones cause?
Estrogen and testosterone cause growth at puberty and closure of epiphyseal plates and the cessation of growth.
Increased stress causes what to the bones?
increase in strength
what is fracture classification based on?
mechanism of fracture
soft-tissue damage
displacement versus nondisplacement
fracture pattern
number of fragments in the fractured bone
age specific
what are the possible mechanisms of fractures?
traumatic
disease
pathologic
when trying to classify soft tissue damage you have to analyze?
closed versus open
types of fracture patterns
linear
spiral
avulsion
stress
compression
The number of fragments in the fractured bone is?
incomplete
complete
communited
when looking at age specific fracture classification what must we identify?
greenstick and epiphyseal features
The level of calcium in the blood depends upon movement of?
calcium enters bone when osteoblasts create new bone and calcium leaves bone when osteoclasts break down bone
what controls blood calcium levels
parathyroid hormone (PTH)
calcitriol
calcitonin
what are the direct affects of the parathyroid hormone (PTH)?
Activates osteoclasts, increases number of osteoclasts, and prevents inhibition of osteoclst formation.
more osteoclast activity impacts the bone how?
Bone is reabsorbed and calcium released into blood.
calcitriol does what and is from where?
Increases blood calcium by stimulating intestinal absorption of calcium.
Derived from vitamin D3.
calcitonin does what?
lowers blood calcium by inhibiting osteoclast activity
what decreases as the skeletal system ages?
Bone matrix decreases and bone mass, posture and potenially teeth
when does bone mass decrease and which sex has denser bone?
after 30 years old and men due to testosterone and greater weight
what is the structural classification of joints based on?
the major connective tissue type that binds the bones together
what are the three major structural categories of joints?
Fibrous
Cartilaginous
Synovial
which structural joint type is bound by dense fibrous connective tissue?
Fibrous joint
Which structural joint type is united tightly by cartilage?
Cartilaginous joint
which structural joint features a joint cavity surrounded by a membrane?
synovial joint
what is the functional classification of joints based on?
the degree of motion allowed
what are three functional categories of joints?
synarthrosis
amphiarthrosis
diarthrosis
what is synarthrosis?
a non-movable joint
what is an amphiarthrosis?
a slightly moveable joint
what is a diarthrosis?
a freely moveable joint
Characteristics of fibrous joints?
united by fibrous connective tissue (strong threads that lock bones together tightly)
have no joint cavity (two bones are directly cemented together by solid collagen fibers; designed for protection rather than movement (shock absorber))
move little or none (cement or heavy duty rivets holding bone in place against one another)
Bones farther apart than suture and joined by ligaments
some movement may occur
(Ex. radioulnar (intreosseus membrane)
syndesmoses