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which imaging techniques do not use ionizing radiation?
MRI and ultrasound
what imaging techniques use ionizing radiation?
CT, X-Ray, PET
what two phenomena explain X-ray generation
Brehmsstrahl reaction and characteristic radiation
what two phenomena explain X-ray attenuation
compton scatter and the photoelectric effect
what is the Brehmsstrahl Reaction?
when the high speed electrons are shot at the anode, the electrons slow down as they approach the nuclei in the anode. the lost kinetic energy is converted into an X-ray photon.
what is characteristic radiation?
when the high speed electrons knock out an inner shell electron, an outer shell electron will fill the vacancy. the outer shell electron is moving into a lower energy state when becoming an inner shell electron, so the difference in energy is released as an x-ray photon.
what is the photoelectric effect
when photons hit an atom, a photoelectron is ejected. the leftover atom becomes an ion, and the photoelectron ionizes other atoms
what is compton scatter?
when the x-ray is not fully attenuated by the electron, the leftover photon energy is released at an angle and creates scatter → makes image less detailed
how does the atomic number and density of an atom affect imaging
atoms with high atomic numbers and high density will attenuate more X-rays, appearing white in the image
atoms with low density and low atomic numbers will not attenuate as many X-rays, appearing black in the image
who discovered the X-ray
Roentgen
what is the term for tissues with higher density that attenuate more x-rays
radiodense
what is the term for tissues with lower density that attenuate less x-rays
radiolucent
what makes a CT different from an X-ray scan
takes longer
has a rotating x-ray source
has better detail
higher radiation
what is the similarity between CT and X-ray scans
both create maps of tissue density using x-rays
what is the unit of a CT and how is it rated?
Hounsfield Units are based off the density of water (0). anything denser than water is >0. anything less dense than water is <0.
what is the difference between taking an anterior-posterior vs. posterior-anterior x-ray scan?
AP scan sends x-rays from front to back; creates magnification of mediastinal shadow by 20-25%
PA scan sends x-rays from back to front; creates a clearer image
how does the MRI work
a strong magnet sends different radiofrequency pulse sequences to excite protons. receiver coils read the energy released by the protons when the relax into their new energy level.
why does MRI have great soft tissue contrast compared to other imaging methods?
water and fat have lots of protons, so they react well to radiofrequency pulses compared to x-rays that are based off of density
types of MRI images
t1-weighted and t2-weighted
what happens in a t1-weighted image and what does it highlight
a short TR and TE highlights fat; good for structure detail and anatomy
what happens in a t2-weighted image and what does it highlight?
a longer TR and TE which highlights water and fluid containing spaces; good for pathology of tumors, edemas, etc.
strengths of MRI
no radiation (good for women and children), good soft tissue contrast
weaknesses of MRI
expensive, inaccessible, takes longer to generate images, strong magnet may have complication risks
what is the longitudinal axis of an MRI
the time it takes for a proton to realign with external magnetic field
what is the transverse axis of an MRI
time it takes for protons to relax to a new baseline frequency
how does an ultrasound work
high frequency sound waves travel through tissue and are reflected back to a probe to generate an image
what is a hypoechoic tissue
a tissue that reflects little/no ultrasound signals → appears black
what is a hyperechoic tissue
tissue that reflects lots of ultrasound signals → appears white
what kind of images will low frequency ultrasound create
low resolution but better depth
what kind of images will a high frequency ultrasound create
high resolution but poor depth
what is acoustic window and how does it work?
using fluid filled spaces to get a better view of deeper structures. this occurs because the sound waves travel well through the fluid, creating a better image,
applications of ultrasound
pregnancy, evaluating heart function, blood clots, muscles and tendons, and abdominal organs
what is an echocardiogram and what is it for
ultrasound of the heart that gives anatomical and functional information in real time → can show contractility, blood flow, and anatomy
what is hypertrophic cardiomyopathy and what is its etiology and prevalence?
thickening of the septum or left ventricle of the heart, causing blockage of the aorta, which can lead to sudden cardiac death.
occurs in 1/500 and is the leading cause of SCD in the young.
what is the leading cause of death in men and women
cardiovascular disease; 1/5 women
what is the most common genetic myopathy?
hypertrophic cardiomyopathy
best noninvasive test for coronary artery disease assessment
CT
acute chest pain, normal enzymes, normal/non-diagnostic ECG may indicate what?
coronary artery disease
first line of imaging for the chest
chest x-ray
uses for chest x-ray
emergency line placement
post surgical imaging
pneumonia, pneumothorax
shortness of breath
what does blunted costophrenic angles indicate
pleural effusion (fluid buildup) or thickening
pneumothorax cause
air enters the pleural cavity, disrupting surface tension and collapsing the lung
types of pneumothorax
open pneumothorax: pleural cavity pressure < atm pressure
closed pneumothorax: pleural cavity pressure = atm pressure
tension pneumothorax: pleural cavity pressure > atm pressure
strength of CT scan
great bone and lunge anatomic detail
good contrast and spatial resolution
can do CT angiography, cinematic rendering
weakness of CT scan
high radiation
weight limit
possible complications
ray tracing
simulation of how light rays bounce off objects when 3d rendering
global illumination
figuring out shadows, depth, and contrast in 3d rendering
what is cinematic rendering
3d rendering using cross sectional images to make them photorealistic
differences between cinematic rendering and volume rendering
lighting model
realism
detail
computation amount
advantages of cinematic rendering (CR)
enhanced realism and clarity for visualization of anatomy
effective communication
chance for innovative research and accurate surgical planning
improved diagnosis
cons of cinematic rendering
high computational demands
can’t be used as a standalone diagnostic tool
potential for artifacts
what is the precentral gyrus made of
grey matter
what is the internal capsule made of
white matter
what is the function of the caudate and lentiform nuclei
tuned movements
types of ultrasound probes
linear, curvilinear, phased array
what is a linear probe for?
low imaging depth; arteries, veins, soft tissue, musculoskeletal system, breast, pleura, eyes, testes
what is a curvilinear probe for
medium imaging depth; abdominal organs, abdominal aorta, abdominal free fluid
what is a phased array probe for
deep imaging depth; heart, lungs, abdomen, pleura, inferior vena cava
ultrasound artifacts
acoustic shadowing, color doppler, comet tail, mirror image, reverberation
what is refraction and what does it cause?
when an ultrasound wave hits a surface and changes its angle of insonation; causes some edges to be brighter than others and can cause acoustic shadowing or mirror image
what is acoustic shadowing
when an ultrasound wave refracts or is completely absorbed by a high density structure, obstructing the view of structures below/behind it
what is mirror image
when an ultrasound wave bounces off a structure and strikes another mass, causing the wave to take longer to return to the probe. this creates a duplicate of the mass.
what is reverberation
when ultrasound waves bounce off the probe or off a returning surface and creates lines and reflections
what is comet tail
when an ultrasound wave bounces off a highly reflective object (ie. calcification), it may cause linear reverberation below the object
what is twinkling phenomenon
when intrinsic ultrasound waves bounce within the machine and cause alternating colors below a reflective object in color doppler mode
what is b-mode for
brightness mode is the a-mode but it scans th whole plane
what is m-mode for
motion mode is used to show movement over time (contractility over time)
what is color doppler for
shows direction and velocity of flow; blue=away from transducer, red=towards transducer
cinematic rendering process
collection of data
assigning opacity and colors to different voxels
path tracing (monte-carlo)
image generation
what is mote-carlo path tracing
a formula/equation used to calculate and integrate all the different light scattering from different directions to reduce compuation