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homeostasis, feedback loops, disease, pathogens, immune system, vaccines
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homeostasis
the process by which the body maintains a constant, stable, balanced internal environment, despite changes in the external environment
conditions the body must keep stable in order to maintain homeostasis
temperature, blood glucose, pH (acidity), oxygen and carbon dioxide levels
ways your body cools you down
sweating, flushing (red face), vasodilation
ways your body warms you up
shivering, raising hairs (goosebumps), paleness of skin, vasoconstriction
what is shivering?
involuntary, small muscle contractions
how does sweating cool you down?
when sweat evaporates it removes heat from your body which cools you down
vasoconstriction
narrowing of blood vessels to reduce heat loss.
vasodilation
widening of blood vessels to increase heat loss
receptor
protein that detects a stimulus and performs an action in response
mechanoreceptor
detects pressure, touch and sound
thermoreceptor
detects changes in temperature
photoreceptor
detects light
chemoreceptor
detects chemical stimuli (molecules in air, food or blood)
examples of mechanoreceptors in body
skin and ear
examples of thermoreceptors in body
skin and central nervous system
examples of photoreceptor in body
retina of the eye
examples of chemoreceptors in body
nose, tongue and blood vessels
control centre
processes information and determines response
where does the control centre recieve information from?
the receptors
where does the control centre send the processed information to?
the effectors
effectors
organs/glands/muscles that work to reverse the change
response
the body will act and return to homeostasis
negative feedback loop
a feedback loop that does the opposite of what the original stimulus does
positive feedback loop
a feedback loop that amplifies what the original stimulus does
place in order: effector, response, stimulus, receptor, control centre
stimulus -> receptor -> control centre -> effectors -> response
thermoregulation
internal regulation of body temperature
what is the optimal temperature for humans to operate at?
37 degrees celcius
central nervous system (CNS)
a processing centre that manages everything your body does
name two body parts that are part of your CNS
brain and spinal cord
peripheral nervous system (PNS)
the nerves that connect the cns to the rest of your body
what does pns do
it sends info to different body parts and carries out commands from brain to various body parts
brain parts
cerebrum, cerebellum, brain stem
cerebrum
wrinkled tissue - most of the brain. responsible for many functions e.g. senses, personality, language, etc.
cerebellum
controls complex muscle movement
brain stem
connects cerebrum to spinal cord.
pathogen
a microorganism that causes disease by feeding off the host - causes infectious disease
disease
when body cannot function normally
living pathogens
bacteria, fungi, parasites, (protists)
non-living pathogens
viruses and prions
virus
microscopic, acellular (does not have a cell structure) and needs to live inside a host to survive (intracellular).
prion
misfolded protein particle that causes disease
bacteria
microorganism which is unicellular and lacks a nucleus (prokaryotic). Can multiply rapidly and cause disease.
fungi
organisms with a nucleus (eukaryotic) which feeds on other organisms.
salmonella (food poisoning) - infectious or non infectious, if applicable what pathogen?
infectious, bacteria
influenza - infectious or non infectious, if applicable what pathogen?
infectious, virus
cancer - infectious or non infectious, if applicable what pathogen?
non infectious
malaria - infectious or non infectious, if applicable what pathogen?
infectious, parasite
mad cow disease - infectious or non infectious, if applicable what pathogen?
infectious, prion
diabetes - infectious or non infectious, if applicable what pathogen?
non infectious
strep throat - infectious or non infectious, if applicable what pathogen?
infectious, bacteria
athletes foot - infectious or non infectious, if applicable what pathogen?
infectious, fungi
ringworm - infectious or non infectious, if applicable what pathogen?
infectious, fungi
lice - infectious or non infectious, if applicable what pathogen?
infectious, parasite
COVID-19 - infectious or non infectious, if applicable what pathogen?
infectious, virus
endemic
disease that is constantly present in a particular area or population
epidemic
a sudden increase in cases of disease above what is expected in a population or area
pandemic
when a disease spreads over multiple countries or continents and affects a large number of people
immune system
protects the body from pathogens
define 'innate'
born with
innate immune system
a barrier against pathogens, often is the first and second lines of defence
innate - specific or non-specific?
non-specific
adaptive immune system
a response to antigens by producing antibodies, often slower but more effective
adaptive - specific or non specific?
specific
phagocytes
a type of white blood cell capable of engulfing some types of pathogens
what is the process of a phagocyte engulfing a pathogen called?
phagocytosis
what are the scientific names of B and T cells
lymphocytes
which cell produces antibodies - B or T?
B
which cell identifies and kills pathogens - B or T?
T
how do T cells destroy pathogens?
by binding themselves to a pathogen and killing it
how do B cells destroy pathogens?
by turning into plasma cells and producing antibodies
how do B and T cells fight off disease faster?
by multiplying
what cells are created that remember how to fight of a disease?
memory cells
which immune system remembers how to fight off a disease?
adaptive immune system
first line of defence
line of defence that includes barriers that prevent pathogens from entering the body - non-specific
first line of defence barrier types
physical, chemical or biological
an example of each type of barrier
skin, saliva, stomach acid, good bacteria
second line of defence
If pathogen passes the first line of defense, the second line of defense starts - non-specific
what usually fights off invaders in the second line of defence?
phagocytes
what are some symptoms of the second line of defence?
inflammation - swelling, redness, heat, fever
how many days does it usually take to fight off an infection?
10-17 days
vaccination
the process of giving a vaccine to stimulate the immune system and provide protection against a specific disease.
how do vaccines work?
by inserting a dead or weakened pathogen to produce an immune response
antigen
the thing on the surface of a pathogen that triggers immune response
what disease discovered vaccines?
smallpox
what disease was a weaker version of another serious disease?
cow pox