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Purpose of research literature review
to provide information to guide a high quality study
Primary source for research review
research reports that are descriptions of the studies written by researchers who conducted them.
Secondary Sources research review
Descripition made by someone other than the original researcher.
Major steps and strategies in a Narrative Research Review
Formulate and Refine the primary and secondary research questions
Device search strategy(Identify Keywords, Databases and other sources): Document search decisions and results organize materials
Search for, indenitify, and retrieve primary source material.:Document search decisions and result organize materials
Screen the abstract for relevance: Idenitify new references and new leads + discard sources that irrevelant
Extract and record information from studies.
Critically apraise the studies.
Analyze and intergrate information and search for themes.
Prepare for synthesis/critical summary
Biblographical databases
Database searches that can done on computers and tablets has largest number of research references.
Ancestry Approach
using references cited in recent relevant studies to track down earliest research on the same study
gray literature
studies with limited distrubution such as conference papers and unpublished reports.
Descendant approach
to find a pivolt study we search citation index to find a more recent the study cited the study.
Eligibility criteria
limiting your search through filters
Indentifying keywords
reviews that begins with a bunch of search terms
Pico
Population
Influence/Intervene
Comparison
Outcome
Searching electronic databases
-Coded to facilitate retrieval.
-some are free of charge and some are sold commerically.
-user friendly
-subject heading searching
-keywords
-mapping: a feature that facilitates a search using your own keywords
Boolean
used to expand or delimit a search
boolean operators are: ,or, and not.
Truncation
expands search to include all forms of the root words uses an * (asterik)
Wildcard symbol
a question that can be inserted into middle of a search that can allow alternative spelling
Screening and gathering reference
-Title of the article
-Examine the abstract
-Purge duplicates
-Open access journal
-Retrieve full text of references
Critical Appraisal of Evidence
-Research Critique vs Critical appraisal
-Peer Reviews
-Appraisal of Invidual studies.
-Critical Assement Skills Programme(CASP)
-Evalauting a body of research
Theory
an abstraction that purports to account or explains a phenomena
Grand Theory
A theory attempts to explain large aspects of the human experience
Middle range theory
a that focuses on specific aspects of the human experience
Practice Theory
Highly Specific, Narrow in Scope, and has action orientation
Conceptual Models/Frameworks/Schemes
-Deals with an abstractions assembled in coherent schemes.
-A less formal attempt than theories to explain phenomena
-Do not have formal stances about relationships among phenomena.
Conceptual Maps
-Visual representations about some aspects of reality.
-Uses concepts as building blocks with minimal usage of words.
-Common in qualitative and quantitave research.
Theoretical Framework
Based on a theory
Conceptual Framework
based on a conceptual model
Nursing Metaparadigm/Conceptual model of Nursing
-Human Beings
-Environment
-Health
-Nursing
Commonalities between theories and conceptual models
-cannot be proven: to greater or lesser degrees.
-can serve as a stimuli for research
-can used to generate a hypothesis
Ray’s Adaptation Model
-Humans are viewed as a biopsychosocial adaptive systems who cope with environmental changes with the process of adaption
Orem’s Self Care Deficit Theory
Patients are responsible for their own care only need nurse assistance if they’re unable to meet their own self care needs.
Pender Health Promotion Model
-Health promotion entails activites directed towards developing resources that maintains or enchances a person’s wellbeing.
Kolcaba’s Comfort Theory
Describes comfort existing in 3 forms relief, transcendence, and ease.
-Describes 4 contexts in which patient comfort can occurs; physical, pyschospiritual, environmental, and sociocultural.
Bandara’s Social Cognitive Theory
-Self efficacy concerns people’s belief in their own capacity to carry out particular behaviors.
-Self efficacy expectations influence the behaviors a person choses to perform, their degree of peverance, and the quality of performance.
Use of theories in research
-Testing a theory
-Testing two competing theories
-Using a theory/model as organized structure.
-Fitting a problem into theory
-developing original theory/model.
The numberg code
Developed after nazi crimes were made public in the the numberg trial was international effort to set ethical standards
The declaration of Helsinki
Another set of international set of ethical principals regarding human experimentation was adopted by world medical association
ANA codes of Ethics
a document with interprepative statements that includes principals that apply to nursing researchers
ICN codes of ethics for nurses
Is a statement that guides ethically nurse practice globally.
Belmont Report
Serves as basis for regulations affecting research sponsored by US government
Ethical Dilemna
is situation in which the rights of participants are in direct conflict with the requirements for the study.
Benefience
-freedom from harm and discomfort
-protection from explotation
Respect for Human Diginity
-The right to self determination
-The right to full disclosure
Informed Consent
participants have adequate information about the study, understand the information, and can consent or decline participation voluntarily.
Anonymity
researchers can’t link participants to their data
Confidentiality
is a pledge that any information participants provides will not be reported in a manner that indenitifies them will not be acessible to others
Justice
-The right to fair treatment
-The right to privacy
Instiutional Review Board
they ensure that the proposed research plan meets the federal requirements for ethical research
Vulrenable groups
vulnerable populations may be incapable of giving fully informed consent or may be at risk for unattended side effects based on circumstances
Experiment, True Experiment, Experimental Study
randomized control trial
Quasi Experimental Study
Controlled clinical trial, clinical trial without randomization
Non experimental/Corrential study
observational study
Retrospective Study
Case control study
Prospective Non Experimental Study
cohort study
Group or Condition
Group or Arm
Experimental Group
treatment or intervention group
Dependent Variable
outcome or end point
Experiment
-Randomized Control Trial:
Gold Standard
-Manipulation
-Control
-Randomization
Manipulation
-Doing something to the study particpants
-Experimenter maniuplates the independent variable by administering a treatment (intervention) to some subjects and witholding it from other, by adminstering some other treatment.
-Has interventions: Tailored Interventions/Patient Centered Interventions
Randomization
-Involves placing subjects into treatment conditions at random.
-Approximates the ideal but impossible counterfactual of having some people in mutiple treatment groups simultaneoulsy.
-Basic Randomization
Manipulation examples
No treatment, Alternative Treatment, Placebo, Standard Treatment, Different Dosages of Treatment, and Waitlist
Control group
refers to a group of participants whose perfomance on an outcome is used to evaulate the treatment group on the same outcome
Treatment Group
set of participants in experiment that receives the specific condition, intervention, or variable being tested.
Quasi Randomization
is a method of allocating participants in a manner that’s not strictly random
Stratified randomization
-In which randomization occurs separately for distinct subgroups (eg males and female)
Partial Randomization
people without a strong treatment preference are randomized
Cluster Randomization
which involves randomly assigning cluster rather than people to different treatment groups
Counterfactual
What would happen to same group of people exposed to causal factor if they weren’t exposed to it
Blinding or Masking
The prevention of those involved in a study from having information that could lead to bias.
Bias
any influence that distorts the results of a study and undermines validlity
Single Blind Study
A study in which only one group does not know participants status in terms of the group which they have been assigned to
Double Blind Study
In which two sets of people are blinded in which neither participant nor those who administer the treatment know who is in the experimental or control group
Pottest only design
data on outcome are only collected after randomization and completion of intervention
Pretest pottest design
mixed designs: analyses can examine both differences between groups and changes within the group overtime.
Hawthorne Effect
The effect on outcome resulting from people’s awareness that they participants are under a study
Clinical Trials phase 1
occurs after development of the drug or therapy is designed to establish safety and tolerance to determine the optimal dosae
Clinical Trials phase 2
Involves gathering evidence about interventions praticability.
Clinical Trials Phase 3
A full test of the intervention a randomized control trial
Clinical Trials phase 4
are studies of effectiveness of the intervention in a general population
Evaluation of Research
effectiveness of a program, policy, or procedure.
-assists in decision maker.
Qualy
Measurement of disease burden includes both quality and quantity of life lived.
CER
involves in direct comparsion of two or more health interventions
Health services research
Broad field that studies how organizational structures, processes, social factors, and personal behaviours affect acess to healthcare, the cost and quality of healthcare, people health and well being.
Outcome research
comprises efforts to understand the end results of structure and processes of health care and assses the effectiveness of health care services
Survery Research
Non experimental research involves gathering people’s characteristics, behaviours, and intentions by asking them to answer questions
Secondary analysis
researchers analyze the previously collected data
need assesment
-needs of a group or community
delphi survery
-problem solving
-several rounds of questionnaires
Methodologic Studies
aims at gathering about strategies of conducting quality research
Population
the aggregate cases in which a researcher interested in
Accesible Population
the aggregate of cases that apply to the criteria and that acessible for a study
Target Population
the aggregate of cases which researcher would like to generalize
Translational research
systematic effort to convert basic research knowledge into practical applications to enchance the human well being
Implementation Research
solves problems in the implementation of health care improvements such as new programs, policies, or practices
Replication Studies
Identical to another study.
-Can findings replicated in another setting?
eligibility/inclusive criteria
criteria that specify population characteristics.
-cost
-practical constraints
-people ability to participate
-Design Considerations
-Exclusion Cricteria
Sampling
selection of a portion of the population to represent the entire population
Element
basic unit about which information is collected
Sample
a subset of population elements
Strata
sub populations; mutually exclusive segment of a population
staged sample
sample are sometimes collected in multiple in phases
sampling bias
the systematic over or underrepresentation of segments of the population on key variables.