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What causes Ebola disease?
Ebolavirus (Filoviridae).
Ebola Pathogenesis
Virus infects mononuclear phagocytes → immune response disrupted → virus replicates extensively → capillaries leak and clotting abnormalities develop.
Ebola Epidemiology
Reservoir is believed to be fruit bats; spread through body fluids.
Ebola Treatment and Prevention
Supportive care, monoclonal antibodies, strict infection control.
Ebola High-Yield Facts
Family: Filoviridae
Reservoir: Fruit bats
Transmission: Body fluids
Hallmark: Hemorrhagic fever