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3 flux points of regulation in glycolysis
step 1 (hexokinase converts glucose to g6o)
step 3 (PFK converts g6p into f1,6bp)
step 10 pyruvate kinase converts pep into 2 pyruvate and yields 2 atp
insulin activates ______ and inhibits _____ by _______
glycogen synthase and inhibits phosphorylase by dephosphorylating
glucagon activates ______- and inhibits ______ by
activates phosphorylase and inhibits synthase by phosphorylsizing
PFK is activated by
fructose 2,6 BP , AMP, ADP, P
PFK is inhibited by
atp, citrase
2 methods of fermentation
lactate and ethanol (+ co2) formation
lactate formation
fermentation where pyrvuate is reduced by lactate dehydrogenous
ethanol formation
fermentation where pyruvate releases a co2 (by pyrvuate decarboxylase) into acetylaldehyde and then is reduced by alchol dehydrogenous
fermentation produces
2 ATP without NAD+/NADH or oxygen
gluconeogenesis occurs in
liver and kidneys