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enantiomers:
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3 enantiomers:
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5 emulsifer for parenteral solution
egg lecithin
6 bond angle atom in h2o:
104.5=105(or109)
8 cetrimide o/w:
cationic
9 oleic acidis:
anion (and sodium lauryl sulfate)
10 not o/w:
bee wax
11 what is cationic:
cetylpyridum(cetrimide, benzalkonium cl)
12 hlb for o/w:
8 to 20(5-18)
13 polysorbat use with cortisone why:
solubilizer (wetting agent)
16 jacob disease causative organism:
prion
17 what is the nature of prion?
infectious proteins
22 acacia insoluble in :
alcohol
28 causative agent for meningitis:age 2-10
neisseria
33 combination of drug occur through except:
exclusion
34 in lab pharmacies should not?
touch or cut neoplastic tablet
38 not seen in lab in iron anemia:
high tranferrin
40 not appear in asthma:
5HT
41 pneumoniae ttt by:
amoxcillin (if allergic to penicillin choose: doxycyclin or clarithromycin)
42 leukocytosis:
inc. leukocytes
45 cause miosis:
pilocarpine
46 pilocarpine is:
cholinergic agonist
47 whooping cough ttt:
macrolide AB (incubation-ủ bệnh 1-2 wks)
55 ciplastin what is approriate:
contains platinum (and 2 adjacent Cl)
56 flouride toxicity:
Cacl2
57 definition of molarity:
number of moles in 1 liter solution
62 fats are:
ester of glycerin and fatty acid
63 eye drop weak:
weak acid
64 methyl paraben ester of what:
parahydrohybenzoic acid
64 methyl paraben used as?
preservation
69 what is true for cystic fibrosis:
drugs are metabolite quicker
71 lice quest:
egg about 6mm from shaft
75 aspirin toxcity cause:
respiratory acidosis (& metabolic acidosis)
82 intermediate release tab limiting rate?
dissolution
83 pregnancy safe ? (amiodaron,carbamezepine,acitresin)?
carbamezepine
85 ketone or aldehyde group in:
methadone, prednisolone, camphor, caffein
86 longest-acting opioid:
fentanyl patch (if not present choose: methadone)
88 COPD should not use:
pholcodine
89 cholinergic crisis with treatment of which disease?
myasthenia gravis
90 cretinism which ion decrease:
iodine
94 starch?
disintegrant
103 polysorbate+coal tar?
dispersant
106 causative micro organism for impetigo?
S.aureus& strept. pyogen
109 stock law, factors affecting it?
density (viscosity), specific gravity,particle size
115 UV range:
200-400
116 loading dose depend on:
Cp0 and Vd
117 procain degradation?
hydrolysis (&penicillin)
120 preparation of KI?
Ki-h2o-iodine-pepermint&glycerin
124 shingles appear after:
72hrs
125 CHCl2 (dichloromethane) moa
monotropic (homotropic)
134 GTN in ?
amber bottle(light resistant bottle)
140 antifactor Xa is used for measuring apixaban?
incorrect
146 factor for vitamin K?
2.7.9.10
150 dabigatran metabolized by conjugation(only phase 2)
by the liver
158 ethylen oxide sterilization:
alkylation
159 most channel in epilepsy:
na. chan.
161 psoriatic lession:
keratinocytes
162 insecticide:
kill egg and nit
166 not true about TNF:
antiviral
168 hemodialysis:
polar compounds
170 NE precurosr:
tyrosin
171 serotonin precursor:
tryptophan
175 true about enatiomers:
not superimposed
176 vitamin not related to eye:
vit d
177 wrong for suppositories;
melt below 30
181 hydroxylated steroid metabolized by;
glucuronidation
181 steroid phase 1&2 metabolism;
hydroxylation then glucuronidation
182 role of Na or Ca in Ca edetate;
inc. stability
183 hypemellose in morphine;
coat
186 anaphylactic reaction;
occur within minutes
186 anaphylactic reaction;
after 2nd exposure
188 dry powder sterilized'
160 celcius in 2hrs
193 not aromatase inhibitor;
Nillutamide
194 most in blood;
erythrocyte
195 velocity fastest in;
arteries
196 lipophilicity;
propanolol>metoprolol>atenolol
199 chondrocyte in osteoarthritis:
tophi in gout, pannus in RA
200 least to produce ATP;
pentose phosphate pathway
206 not in parkinson;
dyskinesia (or hyperreflexia if present)
207 when holding chemotherapeutic drug, which is wrong;
crushing tablet should only be done by pharmacist
217 legionella ttt;
NO amoxicillin ( azithromycin, clarithromycin, doxycycline)
226 emulsion stability depend on;
difference between density
229 not factor in determining therapeutic approach in breast cancer ttt;
age of pt
230 not induce seizures;
loud noise (&moderate excercise)
231 diabetic ketoacidosis;
ketone body production
232 CSF not true:
used as a antiviral
233 phenolbarbital toxicity ttt
give o2 supplement
234 should be absorbed in the intestine to provide action;
methionine
237 which organism cause pyelonephritis;
e.coli
238 pt take IV infusion, dose Css affected by;
t half
242 term used for bluish discolouration of nails and toes;
cyanosis
246 not given in copd;
mast cell stabilizer
249 oily cream incorrect;
aqueous base
253 protein structure, select best;
sequence of amino acid structure
255 boiling protein with ethylen dioxide;
alkylation
259 metered dose inhaler, incorrect?
dont shake before use
260 cyp enzyme (metabolite site);
ER (endoplasmic reticulum)
261 atropine toxicity;
dilate pupil
263 wrong about alkaloids;
pka less than 7
271 not used in Cytomegalovirus;
famyclovir