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Acetylcholine
Primary neurotransmitter transmitting signals from nerve cells to muscles, glands, and other cells.
Actin filament
Thin filaments found in a sarcomere.
Action potential
Special type of electrical signal that travels along a cell membrane as a wave.
Depolarization
Process where internal membrane potential of excitable cells becomes more positive.
Excitation-contraction coupling
Process linking a nervous system action potential to mechanical contraction.
Motor end plate
Location of ACh-receptors in the muscle fiber sarcolemma.
Muscle tension
Mechanical force generated by muscle fiber contraction or stretching of elastic structures.
Myasthenia gravis
Chronic autoimmune disorder causing fluctuating weakness and rapid fatigue in skeletal muscles.
Myosin filament
Thick filaments found in a sarcomere.
Neuromuscular junction
Specialized chemical synapse between a motor neuron and a skeletal muscle fiber.
Neurotransmitter
Chemical messengers allowing neurons to communicate with each other or muscles.
Refractory period
Brief interval immediately following an action potential where an excitable cell recovers.
Repolarization
Plasma membrane of a muscle fiber returns to its negative resting state after depolarization.
Sarcoplasmic Reticulum
Specialized form of smooth endoplasmic reticulum found in striated muscle cells.
Sliding Filament theory
Scientific explanation for how muscle fibers contract to generate force.
Synaptic cleft
Microscopic physical space or gap between a presynaptic and postsynaptic neuron.
Synaptic vesicles
Small, spherical, membrane-bound organelles inside presynaptic nerve terminals.
Terminal cisternae
Enlarged, sac-like regions of the sarcoplasmic reticulum that store and release calcium ions.
Triads
Three-part structure that plays a vital role in triggering muscle contraction.
T-tubule
Deep, branching inward folds of the sarcolemma in striated muscle cells.