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What is dosage compensation?
A mechanism balancing expression of X-linked genes across different X-chromosome numbers.
What is X-inactivation?
Silencing most genes on one X chromosome in typical XX mammalian cells.
What is a Barr body?
A highly condensed, mostly inactive X chromosome.
Why do calico cats have different fur-color patches?
Different cells inactivate different X chromosomes, creating mosaic expression.
What does XIST RNA do?
It coats the X chromosome being inactivated and contributes to silencing.