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Last updated 2:08 AM on 10/3/26
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7 Terms

1
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what is chromosome painting

chromosome labeling techniques that uses chromosome specific DNA probes each labeled with different color (flurochrome) for hybridization with a chromosome completement

2
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what is SKY and FISH

spectral karyotyping

fluorescence in situ hybridization

3
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what is dosage compensation

regulates X linked genes such that their activities are equal in males and females

  • in mammals this results in random inactivation of one X chromosome in females

    • X inactivation


4
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what is the single active X principle hypothesis

after the very early stage embryo, the female body will randomly inactivate one of its X chromosomes in each cell

  • makes sure there is not too many X gene related products


5
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what is the Barr body

a darkly stained body found in the interphase nucleus of certain cells in female mammals

  • it is the condensed inactived X chromosome


6
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do different types of tissue undergo X inactivation at the same or different times

different

7
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is the X chromosome that gets inactivated standardized

no