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Nicotine (NicoDerm, Nicorette, etc.) Pharm class
Nicotine replacement therapy
Nicotine (NicoDerm, Nicorette, etc.): MOA
Minimizes withdrawal by providing nicotine without the carcinogens in tobacco.
Nicotine (NicoDerm, Nicorette, etc.): Indication
Gradually decrease nicotine dose so the patient can quit smoking altogether.
Nicotine (NicoDerm, Nicorette, etc.): S/Es
All the negative effects of nicotine.
Nicotine (NicoDerm, Nicorette, etc.): Considerations
Intended as a way to quit smoking, not an ongoing source of nicotine.
Varenicline (Chantix): pharm class
Smoking cessation
Varenicline (Chantix): MOA
Acts in the brain to reduce pleasurable effects of nicotine.
Varenicline (Chantix): Indication
Helps to quit smoking
Varenicline (Chantix): S/Es
N/V, headache, flatulence, insomnia, taste disturbances
Varenicline (Chantix): Considerations
12 week regimen, very effective
Bupropion (Wellbutrin, Zyban): pharm class
Smoking cessation and anti depressant
Bupropion (Wellbutrin, Zyban): MOA
Acts in the brain to reduce the pleasurable effects of nicotine.
Bupropion (Wellbutrin, Zyban): Indication
Helps to quit smoking
Bupropion (Wellbutrin, Zyban): S/Es
Drowsiness, anxiety, insomnia, dizziness, headache.
Bupropion (Wellbutrin, Zyban): Considerations
Avoid alcohol, may make side effects worse.