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Digestive System
body systems consisting of the GI tract and accessory structures
(liver, pancreas, and gallbladder)
What is the main function of the digestive system
break down food, absorb nutrients, and eliminate waste
What is the main function of the GI tract
digestion and absorption of nutrients
Types of digestion
Mechanical: physical breakdown of food for digestion/absorption of nutrients
Chemical: breakdown of large nutrient molecules in food into short components
GI Tract
Mouth, esophagus, stomach, small intestine, large intestine, and the rectum
Mouth (oral cavity)
preforms chemical and physical digestion
(amylase: produced in saliva and breaks down carbs)
saliva contains: amylase (starch digestion), lipase (fat digestion), and mucus (lubricant)
taste receptors: unami (broth, meaty, and savory flavors) and oleogustus (taste for fat)
Esophagus
primary function: transfer the bolus (mass of moistened swallowed food) into the stomach - regulates the movement of food
esophagus sphincters: upper (opens to let food from the throat to the esophagus) and lower (closes the opening of the esophagus to the stomach)
muscular tube-10 in. long
connects the throat (pharynx) to the stomach
(no digestion/absorption)
Stomach
Primary function: temporarily stores, mixes, and dissolves ingested food
chyme: mixture of stomach secretions and partially digested food
pyloric sphincters: controls the rate of chyme release into the small intestine
gastric secretions- gastric juice: water hydrochloric acid enzymes
HCI (hydrochloric acid): activates digestive enzymes and partially digests food protein
Small Intestine
Primary function: primary site for nutrient digestion and absorption
Consists of 3 sections: duodenum (main site for chemical digestion), jejunum (main site for absorption of nutrients), and Ileum (absorbs the remaining nutrients)
Villi: fingerlike protrusions that help digestion and absorption
absorption cells: intestinal cells that line villi and participate in nutrient absorption
microvilli: helps digest proteins and carbs
Nutrient Absorption Process
Passive Diffusion: nutrients move from the cell membrane higher to lower concentration — no energy/carrier
Facilitated Diffusion: uses carrier protein to move nutrients from higher to lower concentration — no energy but requires protein
Active Absorption: moves nutrients from lower to higher concentration — requires both energy and carrier
Large Intestine
made up of five segments:
cecum: absorbs water, electrolytes, and salt
ascending colon: absorbs remaining cecum nutrients
transverse colon: good bacteria breaks down fiber
descending colon: stores and solidifies waste
sigmoid colon: holding chamber for solid waste
The Rectum
Last portion of the large intestine
Anal sphincters: help control expulsion
Accessory Organs
Liver: processes and stores nutrients, synthesizes cholesterol, and makes bile
Galbladder: stores bile
Pancreas: produces and secretes digestive enzymes to neutralize the highly acidic chyme
Probiotics
live microorganisms from food or supplements that can have beneficial effects on the body (adequate amount)
found in fermented foods and supplements (has to be live/active)
killed in heat
Prebiotics
selectively fermented ingredients that result in specific changes in composition and activity of gas
Postbiotics
metabolic by products of microorganisms that colonize the human body
Parabiotic
inactivated cells or cell extracts of probiotic microorganisms that may confer
Symbiotic
combination of pro/pre biotics taken to confer health benefits on host
Gut Microbiome
promotes a healthy gut in which probiotics, prebiotics, and postbiotics reduce inflammation toxins and improve the immune system
indigestible protein, sugar, and antacids + antibiotics can increase chances for diseases
Irritable Bowel Syndrome (IBS)
hard time digesting certain carbs
symptoms: abdominal pain, gass, bloating
treatments: elimination diet, limit caffeine intake, low fodmaps
FODMAP Diet
limit short chain carbs
Fructose: fruit sugar
Lactose: sugar in milk
Fructose: wheat garlic
Galactans: beans, lentils
Polyols: avocado, cherries
Inflammatory Bowel Disease
Crohn’s Disease: mostly in the ileum but also all layers of the intestine
Ulcerative Colitis: ulcers or cores in the colon/rectum
Celiac Disease: chronic, immune-meditated disease precipitated by exposure to dietary gluten in genetically predisposed people
—Symptoms: cramps, fatigue, weight loss, anemia, infertility, and bone loss
Non-Gluten Celiac Disease
no as much damage in the small intestine but still the same symptoms
Carbohydrates
main fuel source for the brain, nervous system and red blood cells
(single/complex)
4 kcal/gram
Glycogen: storage form of glucose in the body— regulates blood glucose
Simple: one sugar- monosaccharide (1) + disaccharide (2)