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anatomy
structure
physiology
function
homeostasis
-maintenance of a stable internal conditions, without changing outer enviornments
-maintains optimal range
-uses negative feedback loops
the body is in the state of _____ equilibrium
dynamic;
meaning it is consintnly changing
negative feedback loops
body does oppostie, if blood sugar goes up body brings it back down
how does negative feedback work
stimulus (the signal)
receptor (what grabs onto the signal)
integration (decision to FIX the problem)
effector (where the body CORRECTS), if too hot body sweats to cool off
positive feedback
amplifies stimulus and once stimulis is gone it will stop
it strengthens a change and pushes it further in the same direction until a specific event is completed.
examples of positive feedback
Childbirth: Contractions release oxytocin, which makes contractions stronger until the baby is born.
Blood clotting: Platelets attract more platelets until the wound is sealed.
electrolytes
salts, acids, and bases that ionize in water, into ions
these give electrical signals
things put into water make mixtures… what are the three types of mixtures
solution, colloid and suspension
(blood is all there types of mixtures)
solution mixture
easy to pass through membrane, clear becuase small particles
ex- sugar in coffee, glucose in blood
colloid mixture
cloudy, does not pass through membrane becuase a bit bigger particles, but do not form participation
ex- proteins in blood
suspension mixture
cloudy-opaque, parcipitation
ex- fats in blood, blood cells, cornstartch in water
carbohydrates in the body
energy source
lipids in the body
hydrophobic
main ones- cholesterol, fatty acids, phospholipids, triglycerides
cholesterol
in cell membrane, precursor to steroids
fatty acids
precursor of triglycerides and a source of energy
phospholipids
major factor in cell membrane and aids in fat digestion
cell membrane foundation ( with hydrophilic head and hydrophobic tail )
triglycerides
primary energy storage, thermal insulation, filling space by binding organs together, cushioning organs
proteins in the body
monomers- amino acids
peptides- short chain
protiens- long chain
what do the proteins need to do in order to function
fold to function
helps with structure, communication, membrane transport, enzymes, and movement
nucleic acids
made of nucleotides (monomers), most important is ATP
important for DNA and RNA
ATP
used for everything, happens during hydrolysis when bonds break they release energy
types of diffusion
simple diffusion, carrier fac diffusion, and channel fac diffusion
for simple diffusion what can pass right through
H20, O2, and CO2
osmosis
diffusion of water through a semipermeable membrane
slow- when going through membrane itself
fast- when there are aquaporins which are water carrier proteins
secondary active transport
uses energy indirectly, ones passive then the active uses that energy to launch against gradient
primary active transpot
use energy directly using atp
intracellular fluid
in cells
intersitutial fluid
between cells
what concentration do all body fluids have
300 mOsm/L
exocytosis
releases larger items from cell
endocytosis
brining larger material into cell
autocrine signaling
signal to itself
paracrine signaling
signals to neighboors
endocrine signaling
signals carry to blood, then can travel farh
hormones
circulate in the blood and have access to entire body
only affects cells with receptors that can read the signal
direct cell junctions
gap junctions- communication
channels between cells allowing small molecules to pass to one another for communication
tight junctions
help prevent molecules from passing through the intercellular space between the cells
desmosomes
bind neighbooring cells together holding them together
tissues
groups of cells working together to perform a common function
epithelial tissues
covering and lining tissue
is polar because it lines an envionment
apical and basal surface
avascular- no blood vesseles
regenerative quickly
classes of epithelial tissues
simple- one layer
pseudostratified columnar- looks like many layers, but really only one
stratified- many layers
cell shapes
squamous- looks squished, nucleus is flat
cubodial- cube shaped, nucleus shpere
columnar- column shaped, oval nucleus
form follows function
A body part’s shape and structure are designed to help it perform its job.
structural organizational level hierarchy
atom, molecule, macromolecule, organelle, cells, tissues, organs, organ system, and organism
people share the same basic body plan, but we have small differences that are normal…
Anatomical variation = differences in body structure, such as height, bone shape, or where a blood vessel runs.
Physiological variation = differences in how the body functions, such as heart rate, metabolism, or body temperature.
interdependence of body systems
body systems depend on each other and work together to keep you alive and healthy.
what does it mean in the body when something has a set point
that the body tries to keep it in that range of a set point, like body temp
negative feedback loop example on thermoregulation
Body temperature becomes too high.
The brain detects the increase.
Sweating and widening of blood vessels release heat.
Temperature decreases toward normal.
If body temperature is too low, the body shivers and narrows blood vessels to conserve and produce heat.
negative feedback loop example on blood pressure
Blood pressure becomes too high.
Receptors detect the increase.
The heart slows down and blood vessels widen.
Blood pressure decreases toward normal.
If blood pressure is too low, the opposite happens.
homeostatic imbalance
happens when the body cannot keep its internal conditions within a healthy range.
examples… Diabetes: Blood sugar stays too high or a Fever: Body temperature rises above normal.
The body has two main control systems that maintain homeostasis:
Nervous system: Uses fast electrical signals to create quick, short-term responses.
Example: detecting heat and quickly pulling your hand away.
Endocrine system: Uses hormones carried through the blood to create slower, longer-lasting responses.
what are some examples of energy flowing down a gradient in the body
high pressure to low pressure in blood flow down a pressure gradient
heat flow down thermal gradient
what are the six major elements in the human body
Oxygen (O)
Carbon (C)
Hydrogen (H)
Nitrogen (N)
Calcium (Ca)
Phosphorus (P)
Memory trick: OCHN CaP (“Ocean Cap”).
what is an ion, and what happens when an electrolyte dissolves in water
An ion is an atom or molecule with an electrical charge.
When an electrolyte dissolves in water, it separates into charged ions
what are some of the major ions found in the body
Sodium (Na⁺)
Potassium (K⁺)
Calcium (Ca²⁺)
Magnesium (Mg²⁺)
Chloride (Cl⁻)
Bicarbonate (HCO₃⁻)
what are the three main chemical bonds in the body
covalent, ionic, and hydrogen bonds
covalent bonds
Atoms share electrons. These are the strongest bonds in the body.
ionic bonds
Positive and negative ions attract each other. They are weaker in the body because water can separate the ions.
ionic= ironic opposities attract
hydrogen bonds
A weak attraction between slightly positive and slightly negative areas of molecules. These are the weakest bonds, but many together can provide stability.
water is the universal…
solvent
because it can dissolve many different substances.
When electrolytes dissolve in water, they separate into ions.
hydrophilic substances
water loving— these dissolve in water or mixes with it
like sugar or salts
hydrophobic substances
“Water-fearing”—does not mix with or dissolve in water.
Example: fats or oils.
energy in the body
is the capacity to do work, or move something
chemical bonds store free energy that is then used in the body
Decomposition reaction
A larger substance breaks into smaller substances.
AB → A + B
Synthesis reaction
Smaller substances join to create a larger substance.
A + B → AB
Example: joining amino acids to make a protein.
Exchange reaction
Parts of two substances switch places.
AB + CD → AD + CB
metabolism
all chemical reactions in the body
catabolism
Breaking large molecules into smaller ones, usually releasing energy.
anabolism
forming bonds, storing energy
but requires energy
carbohydrates found in the body
monosaccharides, disaccharides, polysaccharides
how are nucleic acids important for dna
instructions for protein synthesis and transfers hereditary information
how are nucleic acids important for rna
carry out protien synthesis
animal cell three basic parts
cell membrane- acts as barrier separating internal and external
cytoplasm w/ organelles- each have specific functions
nucleus- control center
some basic functions of membrane protiens
receptor, enzyme, channel, gated channel
sending signals or acting as a gate
membrane permeability
how easily a substance can pass through a membrane.
selective permeability
membrane lets some substances cross more easily than others.
solute
what is dissolved
solvent
liquid that dissovles somehting
water is the most common
osmolarity
the concentration of dissolved particles (solutes) in a solution.
tonicity
describes how a fluid affects a cell’s size by causing water to move into or out of it.
Osmotic equilibrium
means there is no net movement of water: water still crosses the membrane in both directions, but equal amounts move each way.
what does vesicular transport do
move larger items by exocytosis and endocytosis
what are the four main types of tissues in the body
epithelial, connective, nervous, and muscular tissues
CT- connective tissue
holds structires together and provides support
CT- cartilage
provides flexible support and cushions joints
CT- bone tissue
provides ridgid support and protects organs
CT- blood
transports oxygen and nutrients and waste
three basic structure to CT
fibers and ground substance, and a small portion of cells
ground substance in CT
components that attract water to form a gel
fibers in CT
provide structural support
from most to least strength…
collagen, elastic, reticular fibers
extracellular matrix consists of
ground substance and fibers
cells in CT
form the fibers and ground substance
like fibroblasts
basic structure to cartilage
have cells called chondrocytes that sit into the lacuna
Chondroblasts come first than mature into chondrocytes
Around them is a firm but flexible matrix made of ground substance and fibers. The type of fiber is the main difference between the three types
Perichondrium: a covering around most cartilage that helps it grow and repair.
what does cartilage lack?
ts own blood vessels or nerves. Nutrients must slowly move in from nearby tissue through diffusion, so cartilage heals slowly.
has to be thin to stay alive!
hyaline cartilage
tough with a small amount of flexibility
ex. nasal cartilage
elastic cartilage
tons of elastic fibers, so very flexable
ex. ear cartilage
fibrocartilage
very tough, think areas of pressure and stretch
ex. invertabral disk
appositional growth of cartilage
new cartilage formed on the edges. Chondroblasts beneath the perichondrium add new cartilage to the surface, making it thicker.
perichondrium → chondroblasts → new layers outside.