GAE - BSCI207 Unit 2

True or false?

→"Ultrabithorax mutant flies have four wings because an additional T2 segment is duplicated and inserted where the T3 segment would normally be and inhibits the T3 gene expression."

False

Which of the following is true?

• Hox genes are named for the homeobox DNA-binding protein domain they all encode.

• Mice, like fruit flies, have Hox genes.

• Mouse Hox genes, like those of fruit flies, are required for segment identity.

• Hox genes' arrangement on the chromosome is collinear with their embryonic expression pattern.

• all of the above

All of the above

Which of the following is true?

• The Pax6 gene evolved independently in different animal phyla.

• Pax6 is necessary for eye development in mice, but not flies.

• Pax6 is so conserved that the mouse Pax6 gene can direct eye development in flies.

• Pax6 is necessary for eye development in flies, but not in humans.

Pax6 is so conserved that the mouse Pax6 gene can direct eye development in flies.

TRUE/FALSE: Hox genes are completely different genes between organisms with different body plans

False

Which is NOT true about Hox genes in mice and flies?

• Mice have many more copies of each Hox gene due to whole genome duplications in vertebrates

• Hox genes only determine limb development in flies

• Mice have many more copies of each Hox gene due to individual gene duplications

• Hox expression determines the fate of the somites in early vertebrate dvelopment

Hox genes only determine limb development in flies