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What is a catalyst
A chemical which speeds up a chemical reaction without being used it itself
What is an enzyme
Biological catalyst , proteins
How do enzymes work
Lock and key model
Enzymes active site is complementary to the active site - specific
Which factors affect enzyme activity (2)
Tenperature and pH
What does denature mean
Active site permanently changes shape
Where is amylase found
Salivary glands
What does amylase do
Starch into glucose
How to test for starch
Iodine
Orange/ brown to blue black
Where is protease found
Stomach and small intestine
What does protease do
Protein into amino acids
What is the test for protein
Biuret reagent
Blue to purple
Where is lipase found
Small intestine
test for lipase
Ethanol
Clear to milky white
What does lipase do
Fats / lipids into fatty acids and glycerol
What is the optimum pH for amylase
7
What is the aim of the amylase RP
To see if the pH increases the rate of reaction of amylase
How does food travel in the digestive system
Peristalsis - muscle contractions
What acid is in the stomach and why
Hydrochloric acid
To kill bacteria and give optimum pH for protease
Which enzyme is found in the stomach and what is it’s optimum pH
Protease 1-2
Stomachs adaptations
Thick muscular walls
Walls havs mucus lining to protect from ulcers
Where is bile made
Liver
Where is bile stored
Gall bladder
Is bile acidic or alkaline
Alkaline
2 jobs of bile
Neutralise stomach acid
Emulsify fat
What does emulsify mean
To break down fat into smaller droplets - to increase surface area
What is lipases optimum pH
8-9
Main function of small intestine
Absorption
What is the function of pancreas
Secrets enzymes
Job of large intestine
Absorb water
What does metabolism mean
The sun of all chemical reactions in the body
3 adaptations of small intestine
Vilis- surface area
Capillaries - maintain concentration gradient
One cell thick - short difffusion distance
Test for glucose
Benedict’s solution at 65•c
Blue - brick red
4 things in blood
Red blood cells
White blood cells
Platelets
Plasma
Function of blood
To transport oxygen and other substances to every cell in the body AND REMOVE WASTE
How are red blood cells adapted
No nucleus
Biconcave
Small and flexible
Thin
Haemoglobin
Define Haemoglobin
Red protein inside red blood cells ro bind to oxygen reversibly to make oxyhaemoglobin
job of circulatory system
To circulate blood around the body
Single circulatory
Blood goes through heart once - lowER pressure
3 blood vessels
Arteries veins capillaries
Double circulatory system
Blood goes through the heart twice - highER pressure
Adaptation of artery
ThickER muscular + elastic wall
SmallER lumen
Function of artery
Carry oxygenated blood away from heart - highER pressure
Vein adaptation
ThinnER muscular + elastic walls
LargER lumen
Valves
Function of veins
Carry deoxygenated blood towards the heart twice- lowER pressure
Function of capillary
Connect arteries to veins
Allow diffusion of substances
Capillaries adaptions
1 cell thick
Walls are permeable
Job of the left side of heart
Pump oxygenated blood towards whole body - highER pressure
job of the right side of heart
Pump deoxygenated blood to the lungs- lowER pressure
Function of atrium
Receive blood
Function of ventricle
Pump blood out of heart
Function of valves
Prevent back flow
Where is pacemaker
Right atrium
What does the pacemaker do
Control heart rate
what are coronary artery
Arteries to supply the heart muscle with blood
What is coronary heart disease
Fat blockages in coronary arteries
Less oxygen to heart muscle
Less pumping
Less oxygen to body
What are causes of coronary heart disease (4)
High cholesterol diet
Lack of exercise
Smoking
Alcohol
Treatments for coronary heart disease
Statin
Stent
Bypass surgery
What does statin do
Lowers blood cholesterol
What does stent do
Holds artery open and wide
What does bypass surgery do
Replaces artery
Wnat is an arrhythmia
Irregular heartbeat
What causes arrhythmia
Coronary heart disease
High blood pressure
Genetic
Treatments for arrhythmia
medicine
Pacemaker device implanted
What is heart valve disease
When valves are leaky
Treatments for heart valve disease
Replace with mechanical or biological valve
Advantages of mechanical valve
Lasts long
No rejection
Disadvantages of mechanical valve
Blood clots - needs meds
Advantages of biological valve
Cheap
disadvantages of biological valve
Rejection - needs meds
What is heart failure
When heart is unable to pump blood around the body
Treatment for heart failure
Heart transplant
Disadvantages of heart transplants
Risk of infection
Waiting list
Rejection - need meds
Why does heart rate increase during exercise
Heart rate increases to provide more blood to muscle cells
So more oxygen and glucose for respiration
So more carbon dioxide can be removed
So more energy can be released
What’s in the respiratory system (8)
Trachea
Bronchi
Bronchioles
Alveoli
Ribs
Lung
Diaphragm
Intercostal muscles
Function of alveoli
Gaseous exchange
Alveoli adaptation (3)
Thin walls- 1 cell thick
Large surface area
Good blood supply - maintain concentration gradient
How do fish do gas exchange
Using gills
gill filaments
How are gills adapted
Large surface area- gill filaments
Good blood supply
Filaments have Thin wall