purine biosynthesis

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Last updated 5:49 PM on 10/15/26
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15 Terms

1
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step 0

substrate: ribose-5P

enzyme: PRPP synthetase

product: PRPP

<p>substrate: ribose-5P</p><p>enzyme: PRPP synthetase</p><p>product: PRPP</p>
2
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step 1

substrate: PRPP

enzyme: glutamine-PRPP amidotransferase

product: 5PRA

<p>substrate: PRPP</p><p>enzyme: glutamine-PRPP amidotransferase</p><p>product: 5PRA</p>
3
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step 2

substrate: 5PRA

enzyme: GAR synthetase

product: GAR

<p>substrate: 5PRA</p><p>enzyme: GAR synthetase</p><p>product: GAR</p>
4
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step 3

substrate: GAR

enzyme: GAR transformylase

product: FGAR

<p>substrate: GAR</p><p>enzyme: GAR transformylase</p><p>product: FGAR</p>
5
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step 4

substrate: FGAR

enzyme: FGAM synthetase

product: FGAM

<p>substrate: FGAR</p><p>enzyme: FGAM synthetase</p><p>product: FGAM</p>
6
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step 5

substrate: FGAM

enzyme: AIR synthetase

product: AIR

<p>substrate: FGAM</p><p>enzyme: AIR synthetase</p><p>product: AIR</p>
7
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step 6

substrate: AIR

enzyme: AIR carboxylase

product: CAIR

<p>substrate: AIR</p><p>enzyme: AIR carboxylase</p><p>product: CAIR</p>
8
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step 7

substrate: CAIR

enzyme: SAICAR synthetase

product: SAICAR

<p>substrate: CAIR</p><p>enzyme: SAICAR synthetase</p><p>product: SAICAR</p>
9
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step 8

substrate: SAICAR

enzyme: SAICAR lyase

product: AICAR

<p>substrate: SAICAR</p><p>enzyme: SAICAR lyase</p><p>product: AICAR</p>
10
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step 9

substrate: AICAR

enzyme: AICAR transformylase

product: FAICAR

<p>substrate: AICAR</p><p>enzyme: AICAR transformylase</p><p>product: FAICAR</p>
11
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step 10

substrate: FAICAR

enzyme: IMP synthase

product: IMP

<p>substrate: FAICAR</p><p>enzyme: IMP synthase</p><p>product: IMP</p>
12
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step 11 (AMP)

substrate: IMP

enzyme: adenylosuccinate synthetase

product: adenylosuccinate

<p>substrate: IMP</p><p>enzyme: adenylosuccinate synthetase </p><p>product: adenylosuccinate</p>
13
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step 12 (AMP)

substrate: adenylosuccinate

enzyme: adenylosuccinate lyase

product: AMP

<p>substrate: adenylosuccinate</p><p>enzyme: adenylosuccinate lyase</p><p>product: AMP</p>
14
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step 11 (GMP)

substrate: IMP

enzyme: IMP dehydrogenase

product: XMP

<p>substrate: IMP</p><p>enzyme: IMP dehydrogenase</p><p>product: XMP</p>
15
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step 12 (GMP)

substrate: XMP

enzyme: GMP synthetase

product: GMP

<p>substrate: XMP</p><p>enzyme: GMP synthetase</p><p>product: GMP</p>