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Three factors determining degree of cell activation
Blood levels of hormone, number of receptors for hormone, Affinity of binding between receptor and hormone
Receptor protien
Binds to a hormone to activate target cell
Adrenocorticotropic (ACTH)
receptor protein in adrenal cortex cells
Up-regulation
low concentration of a hormone causes target cells to form additional receptors
Down-regulation
high hormone concentrations decreases the number of receptors