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pulmonary embolism
the blockage of one or more pulmonary arteries by a thrombus, fat or air embolus, or tumor tissue
1. deep veins of the legs (i.e., DVT/VTE)
2. right atrium in patients with a-fib
3. pelvic veins
4. upper extremities
5. long bone fractures (fat emboli)
6. bacteria vegetation on heart valves
7. amniotic fluid emboli
8. tumors
sites of origin of pulmonary embolism (8)
deep veins of the legs (i.e., DVT/VTE)
the most common site of origin of pulmonary embolism
1. dyspnea
2. hemoptysis
3. chest pain
the classic triad in 85% of patients with pulmonary embolism
pulmonary embolism
accentuation of the pulmonic heart sound (split S2) =
massive emboli
sudden collapse with shock, pallor, severe hypoxemia, crushing chest pain, altered mental status, hypotension, and feelings of impending doom
D-dimer
non-specific and not sensitive diagnostic test for pulmonary embolism
< 0.50
normal D-dimer
spiral contrast CT scan
with an elevated D-dimer, confirm diagnosis of a PE with a _____
spiral contrast CT scan
a negative venous ultrasound and positive D-dimer requires a _____ to confirm diagnosis of a PE
pulmonary angiogram
most sensitive and specific diagnostic test for pulmonary embolism
spiral contrast CT scan
diagnostic test for pulmonary embolism that has reduced the need for pulmonary angiograms
1. D-dimer
2. troponin
what labs may be elevated with a pulmonary embolism? (2)
1. IV fluids
2. pressors
3. intubation
interventions to support cardiopulmonary status in patients with a pulmonary embolism (3)
1. TCDB
2. IS
respiratory measures to prevent or treat atelectasis in patients with pulmonary embolism (2)
1. H/H
2. INR
3. PLT
what should be monitored in patients taking heparin (Warfarin) for pulmonary embolism? (3)
2-3
therapeutic INR for patients taking heparin (Warfarin) for pulmonary embolism
enoxaparin (Lovenox)
patients with a pulmonary embolism should bridge with _____ until therapeutic oral anticoagulant therapy can be initiated
3 mo
treatment time for oral anticoagulants for a pulmonary embolism is a minimum of _____ unless therapy is contraindicated
enoxaparin (Lovenox)
safer and more effective anticoagulant than unfractionated heparin
1 mg/kg BID or 1.5 mg/kg QD
therapeutic dose of enoxaparin (Lovenox)
40 mg QD or 30 mg QD with renal insufficiency
prophylactic dose of enoxaparin (Lovenox)
fibrinolytic therapy (streptokinase)
dissolves/breaks down blood clots
EKOS acoustic pulse thrombosis
a minimally invasive procedure that uses ultrasound and medication to dissolve blood clots
inferior vena cava filter (IVC filter)
a small, metal device that prevents blood clots from traveling to the lungs. indicated for high-risk patients with contraindications to anticoagulation
1. misplacement
2. migration
3. perforation
complications of IVC filters (3)
1. pulmonary infarction
2. pulmonary hypertension
complications of pulmonary embolism (2)
right-sided
pulmonary hypertension r/t pulmonary embolism leads to atrial hypertrophy and _____ heart failure
1. early ambulation
2. compression stockings (30-40 mmHg)
3. DVT prevention
4. SCDs
prevention of pulmonary embolism (4)