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development
produces organisms with a defined set of characteristics
growth
increase in size or number of cells
Morphology
structure or form of an organism
Hox genes
series of genes that controls the differentiation of cells and tissues in an embryo
how many planes do our body have?
3
what are the purpose of having different plane/axis?
direct and control tissue
how do cell receives information?
concentration of intercellular and extracellular molecules
morphogens (intracellular)
Signaling molecules that stimulate cell differentiation and development
cell adhesion molecules (CAMs)
-proteins found on surface of most cells
-aid in binding the cell to the extracellular matrix or to other cells
- present with cell to cell contacts
effect of cell positional information
- cell migration within the embryo
- division
- apoptosis: separate tissue
- cellular differentiation: stem cells are being use for different purpose
How is cells distribute asymmetrically?
concentration gradient, positional information
How are the position influenced?
contacts it makes with other cells and extracellular matrix
transcription factor
A regulatory protein that binds to DNA and affects transcription of specific genes.
Tripoblastic
having 3 germ layers: ectoderm, mesoderm, and endoderm
5 stages of embryogenesis
1. fertilization
2. cleavage
3. gastrulation
4. neurulation
5. organogenesis
sometimes metamorphosis
what do sperm use to break through the jelly coat of egg?
hydrolytic enzymes
what happen when sperm enters the egg?
the egg is depolarized to block additional sperm
cleavage
- repeated mitotic cell divisions without cell growth
- daughter cells are blastomere
- solid ball of cells hollows out to form blastula
meroblastic cleavage
incomplete division of the egg, occurs in species with yolk-rich eggs, such as reptiles and birds
vegetal pole
The portion of the egg where most yolk is concentrated
animal pole
The portion of the egg where the least yolk is concentrated and more cytoplasm in egg
holoblastic cleavage
- complete cleavage
- smaller amount of yolk
- amphibians and mammals
- mammal undergo compaction forming a blastocyst
Blastocyst
stage of early development in mammals that consists of a hollow ball of cells
Gastrula
An embryonic stage in animal development encompassing the formation of three layers: ectoderm, mesoderm, and endoderm.
Ectoderm
- outer layer
- skin
- nervous system
Mesoderm
- middle layer
- heart
- limbs
- muscles
- kidneys
- blood
- connective tissues
- notochord
Endoderm
- inner layer
- form lining of gut, liver, pancreas, thyroid, lungs, and bladder
where does cell derived from?
germ layers
Blastopore
the opening of the central cavity of an embryo in the early stage of development.
blastopore (human anus)
the first opening that forms on the surface of an early animal embryo during the gastrulation stage. It connects the embryo's inside cavity to the outside world
Archenteron
the primitive gastric cavity of an embryo
when is gastrulation complete?
when the 3 germ layers are present
what is the precursor for all nerve?
neural crest and the ectoderm
neural tube
an embryonic structure that gives rise to the central nervous system
what do embryo develops during the neuralation?
segmented structures
how does the neural tube form?
1. thickening and elongation
2. folding
3. convergence
4. fusion
what happen in thickening and elongation?
- Ectoderm thickens over the notochord.
- This forms the neural plate.
- The surrounding ectoderm becomes the neural crest and epidermis.
what happen in folding?
- Cells in the middle (medial hinge point) change shape.
- The neural plate folds upward.
- This creates a neural groove.
what happen in convergence?
- The two sides of the neural plate move toward each other.
- Dorsal lateral hinge points help the sides bend inward.
- The folds meet and form a tube-like structure.
what happen in fusion?
- The two sides fuse together.
- This closes the neural tube.
- The epidermis closes over the top.
- Neural crest cells separate and migrate away.
what happen when the neural tube doesn't close all the way?
nutrition deficiency or paralysis
neural crest
- cells on the dorsal side of the neural tube
- unique to vertebrates
- migrate to different regions of the embryo
- from neurons and supporting cells of the peripheral nervous system (PNS)
what does neural crest form?
- peripheral nervous system (PNS): neuron forming and supporting cells
- melanocytes: skin pigment
- facial skeleton and cartilage: face and skull forma
- medulla of the adrenal gland: inner part of adrenal gland
how are segments form?
dividing blocks of mesoderm into somites become ribs, intercostal muscles, and vertebrae
when does organ form?
during or after neurulation
what controls and organize organ development?
hox genes
when does life emerged?
between 4 and 3.5 bya
what do you need before you can have a living cell?
1. polymers
2. information transfer
3. membrane to protect you from damage
4. cellular properties
stages that first cell might have arisen
1. nucleotides and amino acids produced
2. nucleotides and amino acids became polymerized to form DNA, RNA, and proteins
3. polymers became enclosed in membrane (copy molecule)
4. polymers enclosed in membranes acquired cellular properties
how does organic molecules form on earth?
earth may have been more conductive to spontaneous formation of organic molecules
what are the hypotheses of how life were created on earth?
1. reducing atmosphere: stanley miller
2. extraterrestrial: meteorites brought C to earth
3. deep sea vent: molecule formed between extremely hot water vent and cold ocean water
Europa
moon of jupiter
enceladus
Moon of Saturn
where did the organic polymers come from?
clay surface of shallow pools
characteristics of protobiont
1. Boundary separated external environment from internal contents
2. Polymers inside contained information
3. Other polymers had enzymatic function
4. capable of self-replication
Coacervates
droplets that form spontaneously from the association of charged polymers. enzymes trapped inside can perform primitive metabolic function. basically charged ball
liposomes
vesicles surrounded by a lipid layer. clay can catalyze formation of liposomes that grow and divide. can enclose RNA.
Central Dogma
DNA -> RNA -> Protein
what does scientist expect molecule to be able to do?
- store information
- self replicate
- have enzymatic function
what was the first macromolecule of probiotants and why?
RNA because it can store information, self replicate, and have enzymatic function
what can fossils tell us about early earth?
life, climate, and geography
what type of rocks contain most fossil?
sedimentary rocks
how can fossil be dated?
radiometric dating
can anything become a fossil?
no
Hadean Eon
no life on earth
Archean Eon
only prokaryotes
Proterozoic Eon
- first eukaryotes
- multicellular eukaryotes
- define animals: sponges and jellyfish
Phanerozoic Eon
- cambrian explosion of animals; land and plants came later
macroevolution/ major environmental changes can caused by
- climate/temperature, glaciation
- atmosphere, oxygen, humidity, light penetration
- movement of land masses
- floods
- volcanic eruptions
- metrorics impacts
5 mass extinctions
Ordovician, Devonian, Permian, Triassic, Cretaceous
Hetrotroph cells
fed on organic molecules
autotroph cells
evolved as a supply of organic molecules
stomatolites
Rocks built up by ancient photosynthetic prokaryotes (layered) first evidence of life on Earth. Calcium carbonate. produced oxygen as a waste product of photosynthesis.
Mesozoic Era
- dinosaurs
- true mammals
- early birds
- flowering plants
Cenozic Era
- mammals expanded quickly
- angiosperms dominate land plants
- hominids
Homo erectus
- normal size but smaller brain
- use tools, hunted animals, and cook over fires
- extinct abt 100,000 ya
Homo heidelbergensis
- same body and barin size as human
- use tools to hunt
- gave rise to 3 species: H. neanderthalis, the denisovans, and H. sapiens
Homo neanderthalis
- shorter and stockier than heidelbergensis
- conserving heat better
- massive skull and larger brain size
- live in europe
- hyoid bone= speech was used
Homo sapiens
- smaller brain
- body required lower energy
- increased longevity
- social structures and cultural adaptations
does physical differences reflect genetic differences?
no
inherited traits
traits that are passed from parents to their offspring
what is the cause of adaptive evolution?
natural selection
what is natural selection
A natural process resulting in the evolution of organisms best adapted to the environment.
what did darwin notice in population?
variation
2 important points that darwin made
1. modern species have descended from common ancestors
2. natural selection is the mechanism of evolution
populations produce more individuals that can survive =
competition was a factor for all living things
natural selection can lead to ________
evolution
transitional forms
fossils that connect ancestral species with their descendants through a series of tiny steps
Biogeography and its impact on evolution
Study of past and present distribution of organisms. isolated continents and island groups evolve their own distinct plant and animal communities
homology
similarity resulting from common ancestry
vestigial structures (anatomical homology)
A structure that is present in an organism but no longer serves its original purpose
developmental homology
A similarity in embryonic form, or in the fate of embryonic tissues
molecular homology
many species share similar DNA and amino acid sequences. (replication, transcription, translation, respiration, and membrane transport)
Microevolution
Change in allele frequencies in a population over generations.
Alleles
Different forms of a gene
allele frequency
# of copies of an allele/total # of alleles in population
Population
A group of individuals that belong to the same species and live in the same area
gene pool
Combined genetic information of all the members of a particular population
Polymorphism
two or more variations for a given character
polymorphic gene
two or more alleles