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Schizophrenia affects 1% of adults
Characterized by psychosis
-- Altered cognition, perception, and reality testing
75%: Develop gradually, presenting at 15 to 25 years of age
Child-onset and late-onset are more rare
clinical picture (schizophrenia)
Two or more of the following for a significant portion of time in 1 month:
- Delusions (fixed false beliefs)
- Hallucinations (sensing something that isnt here)
- Disorganized speech
- Gross disorganization or catatonia (just existing. not talking or eating etc.)
- Negative symptoms (diminished emotional expression or avolition)
- Functional impairment of some kind
Continuous disturbance for at least 6 months
DSM-V Criteria: Highlights for schizophrenia
Eric M, 18, has always been a good student. However, in his second semester of college, he begins, for the first time in his life, to have trouble concentrating. When his family doesn't hear from Eric, they contact the school, only to discover that his roommate says Eric is "talking weird."
Asked what he means, the roommate says, "Well, you know, he says stuff that doesn't connect, doesn't make any sense. I asked him if he was high or something, but he said no, and I believed him."
On further investigation, Eric's professors say he's been missing class, after starting out so well.
Eric's roommate says his speech "... doesn't connect; it doesn't make any sense. He sort of gets derailed." Which of the following symptoms is Eric displaying?
A. Avolitional speech
B. Delusional speech
C. Disorganized speech
D. Diminished emotional expression
C. Disorganized speech
Childhood-onset schizophrenia: 1 in 40,000 children
No difference related to
- Race
- Social status
- Culture
More frequently diagnosed:
- Among males
- In urban areas
Epidemiology (schizophrenia)
Substance abuse disorders
- Nicotine dependence
Anxiety, depression, and suicide
Physical health or illness
Polydipsia
comorbidity (schizophrenia)
Biological factors
- Genetics
Neurobiological
- Dopamine theory
- Other neurochemical hypotheses
Brain structure abnormalities
Psychological and environmental factors
- Prenatal stressors
- Psychological stressors
- Environmental stressors
- Prognostic considerations
etiology (schizophrenia)
Prodromal phase of schizophrenia
Onset; mild changes
Acute phase of schizophrenia
Exacerbation of symptoms
stabilization phase of schizophrenia
Symptoms diminishing
Movement toward previous level of functioning
maintenance or residual phase of schizophrenia
New baseline is established
Eric agrees to see a psychiatrist and an initial assessment and history indicate that he has only been experiencing some mild changes in his thinking and mood for about a month—ever since returning from the winter holiday. The examiner confirms that his speech is sometimes disorganized and his ability to concentrate and study is diminished from his previous longstanding as a strong student.
Given the evidence we have so far, if Eric has schizophrenia, which is suspected, which phase is he most likely experiencing?
A. Acute
B. Residual
C. Prodromal
D. Stabilization
C. Prodromal

During the prodromal phase
General ______________:
- Positive symptoms
- Negative symptoms (flat, restrictive)
- Cognitive symptoms (mini cog)
- Affective symptoms
assessment (schizophrenia)
Alterations in reality testing
- Delusions—false, fixed beliefs
- Alterations in speech
- Concrete thinking—inability to think abstractly
positive symptoms
Word salad—most extreme form; jumble of words meaningless to a listener
Associative looseness
Words chosen based on sound
Clang association
Meaning for the patient only, Using their own words
Neologisms
Pathological repetition of another's words
Echolalia
Circumstantiality
Tangentiality
Cognitive retardation
Pressured speech
Flight of ideas
Symbolic speech
Abnormal Speech Patterns
Thought blocking
Thought insertion
Thought deletion
Magical thinking
Paranoia
disorders or distortions of thought
During assessment, Eric has trouble staying on topic, zipping rapidly from one thought to the next, making it hard to follow what he's trying to say. Which speech disturbance is he exhibiting?
A.Pressured speech
B.Circumstantiality
C.Flight of ideas
D.Tangentiality
C.Flight of ideas
Depersonalization
Derealization
Hallucinations
- Auditory
- Visual
- Olfactory
- Gustatory
- Tactile
- Command
- Illusions
Alterations in Perception
Catatonia
Motor retardation (slowed)
Motor agitation (restless)
Stereotyped behaviors
Waxy flexibility
Echopraxia (copy motions)
Negativism
Impaired impulse control
Gesturing or posturing
Boundary impairment (intrusive)
Alterations in Behavior
The absence of essential human qualities
- Anhedonia
- Avolition
- Asociality
- Affective blunting
- Apathy
- Alogia
Affect: Outward expression of a person's internal emotional state
- Flat (no emotion at all)
- Blunted (may show slight emotion but nearly flat)
- Inappropriate
- Bizarre
negative symptoms
Concrete thinking
Impaired memory
Impaired information processing
Impaired executive functioning (requiring steps for completion)
cognitive symptoms
Assessment for depression is crucial
- May herald impending relapse
- Increases substance abuse
- Increases suicide risk
- Further impairs functioning
affective symptoms
Inability to realize they are ill
Caused by the illness itself
May result in resistance to or cessation of treatment
Often combined with paranoia so that accepting help is impossible
no insight
Anosognosia
Anxiety or fear
Frustration
Expectations
nonjudgemental culturally appropriate care!!!!!!!
Nurse's self-assessment (schizophrenia)
Eric becomes anxious and says, "There are worms under my skin eating the hair follicles." How would you classify this assessment finding?
A.Positive symptom
B.Negative symptom
C.Cognitive symptom
D. Depressive symptom
A.Positive symptom
Any medical problems
Medical problems that mimic psychosis
Drug or alcohol use disorders
Mental status examination
Include cognitive assessment (e.g., reality testing)
Assess for hallucinations
Assess for delusions
Assess for suicide risk
Assess ability to ensure personal safety and health
Assess prescribed meds
Assess symptoms' impact on functioning
Assess family knowledge
Assessment Guidelines (Schizophrenia)
The psychiatric nurse conducting Eric's assessment believes that he is also suffering from command hallucinations. Discuss what kinds of questions could help affirm this.
are you hearing voices? what are they saying? is it male or female? are there many voices or just one? do you know who it is?
Disturbed sensory perception
Risk for self-directed or other-directed violence
Impaired verbal communication
Positive symptoms - nursing diagnoses
Social isolation
Chronic low self-esteem
Negative symptoms - nursing diagnoses
Phase I—acute
- Patient safety and medical stabilization
Phase II—stabilization
- Help patient understand illness and treatment
- Stabilize medications
- Control or cope with symptoms
Phase III—maintenance
- Maintain achievement
- Prevent relapse
- Achieve independence, satisfactory quality of life
Outcomes Identification (schizophrenia)
After an acute admission, discharge is being planned for Eric. What are some things that need to be considered?
Home life? Medication adherence? Follow up appointments? transportation? orientation? money? fiduciary needed?
Phase I—acute
- Best strategies to ensure patient safety and provide symptom stabilization
Phase II—stabilization
Phase III—maintenance
- Provide patient and family education
- Relapse prevention skills are vital
planning (schizophrenia)
Psychiatric, medical, and neurological evaluation
Psychopharmacological treatment
Support, psychoeducation, and guidance
Supervision and limit setting in the milieu
Monitor fluid intake
Working with aggression
-- Regularly assess for risk and take safety measures
Acute phase - implementation (schizophrenia)
Stabilization and maintenance phases
- Medication administration/adherence
- Relationships with trusted care providers
- Community-based therapeutic services
- Teamwork and safety
- Activities and groups
Counseling and communication techniques
- Hallucinations
- Delusions
- Associative looseness
- Health teaching and health promotion
Interventions (schizophrenia)
Antipsychotic medications
- First-generation (target only + symptoms)
- Second-generation (targets both + and - symptoms, less side effects)
- Other Second-generation/Third-generation
Injectable antipsychotics
- Short-acting
- Long-acting, Table 12.4
Psychobiological Interventions (schizophrenia)
Dopamine antagonists (D2 receptor antagonists)
Target positive symptoms of schizophrenia
Advantage
- Less expensive than second generation
Disadvantages
- Extrapyramidal side effects (EPS)
- Anticholinergic (ACh) side effects
- Tardive dyskinesia (will not go away)
- Weight gain, sexual dysfunction, endocrine disturbances
First-Generation Antipsychotics
Serotonin (5-HT2A receptor) and dopamine (D2 receptor) antagonists, e.g., clozapine (Clozaril)
Treat both positive and negative symptoms
Minimal to no EPS or tardive dyskinesia
Disadvantage—tendency to cause significant weight gain; risk of metabolic syndrome
Second-Generation Antipsychotics
Really a subset of the SGAs
Aripiprazole (Abilify), brexpiprazole (Rexulti), and cariprazine (Vraylar)
Dopamine system stabilizers (stops spikes in dopamine)
May improve positive and negative symptoms and cognitive function
-- Little risk of EPS or tardive dyskinesia
Other Second-Generation/Third-Generation Antipsychotics
ACh toxicity
Neuroleptic malignant syndrome (NMS) - antipsychotic toxicity
Agranulocytosis
Prolongation of the QT interval
Liver impairment
Potentially Dangerous Responses to Antipsychotics
Individual and group therapy
Psychoeducation
Medication prescription and monitoring
Basic health assessment
Cognitive remediation
Family therapy
Advanced Practice Interventions (schizophrenia)
Reevaluate progress regularly and adjust treatment when needed
Even after symptoms improve outwardly, inside the patient is still recovering.
Set small goals; recovery can take months.
Active, ongoing communication and caring is essential.
Evaluation (schizophrenia)
Loose associations in a person with schizophrenia indicate
A.paranoia.
B.mood instability.
C.depersonalization.
D. poorly organized thinking.
D. poorly organized thinking.
Which assessment finding represents a negative symptom of schizophrenia?
A.Apathy
B.Delusion
C.Motor tic
D. Hallucination
A.Apathy
Clinical picture
- Reactive attachment disorder
- Disinhibited social engagement disorder
- Posttraumatic stress disorder (PTSD) in preschool children
Trauma-Related Disorders in Children
Reactive attachment disorder
Disinhibited social engagement disorder
Attachment Disorders
Post traumatic stress disorder (PTSD)
Epidemiology
Comorbidity
Etiology
- Genetic
- Neurobiological
- Psychological
- Environmental
Post traumatic Stress Disorder in Children and Adolescents
Genetic
- How individuals react to trauma
Neurobiological
- Trauma dysregulates neural pathways that integrate emotional regulation and arousal
- Triggers hypoaroused state leading to dissociation
- Polyvagal theory
Environmental factors
- Dependence on adults and systems
- External factors that support or add stress
Etiology: Biological Factors (PTSD in children)
Assessment
- Developmental assessment
Nursing diagnoses
Outcomes identification
Implementation
Evaluation
Application of the Nursing Process (PTSD in children)
Stage 1: Provide safety and stabilization
Stage 2: Reduce arousal and regulate emotion through symptom reduction
Stage 3: Catch up on developmental and social skills; develop a value system
Intervention Stages (PTSD in children)
Establish trust and safety
Use developmentally appropriate language
Teach relaxation techniques
Use art and play to promote expression of feelings
Involve caretakers in 1:1s, unless they are the cause of trauma
Educate child and caretakers about grief process
Assist caretakers in resolving personal distress
Coordinate with social work for protections
Interventions for Child with PTSD
1. The child's safety has been maintained.
2. Anxiety has been reduced, and stress is handled adaptively.
3. Emotions and behavior are appropriate for the situation.
4. The child achieves normal developmental milestones for his or her chronological age.
5. The child is able to seek out adults for nurturance and help when needed.
Evaluation for Child with PTSD
Max, age 6, has been traumatized by a history of violence from an alcoholic father. A neighbor calls the police one night, and the father is taken in for questioning and agrees to enroll in rehab. Max is taken to the hospital for assessment of his arm, which is covered with bruises. His mother is distraught and says she wants help for the whole family, including her husband. The nurse prepares to assess Max's mental health.
The nurse prepares to assess Max's mental health. Identify some broad areas of mental health assessment for this child.
play therapy, assess arm, ask how he is doing, ask about school, adaptability? does he flinch? is he isolated? PTSD? depression?
Before going home from the hospital, Max and his family begin intervention therapy. Which is probably the least useful strategy at this time?
A.Establish trust and safety in the therapeutic relationship.
B.Use art to help Max express his feelings.
C.Bring Max's father into 1:1 play therapy sessions.
D. Teach Max and his parents about grief.
C.Bring Max's father into 1:1 play therapy sessions.
Which of the following should be established first in working with a child with PTSD?
A.Provide safety and stabilization
B.Reduce symptoms
C.Develop a value system
D.Provide support for catching up on developmental and social skills
A.Provide safety and stabilization
Re-experiencing of the trauma
Avoidance of stimuli associated with trauma
Persistent symptoms of increased arousal
Alterations in mood
Assessment
Outcomes identification
- Manage anxiety
- Increase self-esteem
- Improve ability to cope
Implementation
- The same 3-stage model used for children
- Psychoeducation
- Psychopharmacology
Advanced practice
- EMDR therapy
Evaluation
- The patient recognizes symptoms as related to the trauma
- The patient is able to use newly learned strategies to manage anxiety
- The patient experiences no flashbacks or intrusive thoughts about the traumatic event
- The patient is able to sleep adequately without nightmares
- The patient can assume usual roles and maintains satisfying interpersonal relationships
Post traumatic Stress Disorder in Adults
Immediately after a highly traumatic event
Symptoms persist for 3 days
Diagnosis made within month
After 1 month
- Resolution or
- Becomes PTSD
Diagnosis
- Alterations in concentration
- Anger
- Dissociative amnesia
- Headache
- Irritability
- Nightmares
- Related to:
-- Victimization
Implementation
- Establish therapeutic relationship
- Assist to problem solve
- Connect person to supports
- Collaborate for coordination of care
- Ensure and maintain safety
- Refer to a licensed mental health provider
- Monitor response and/or adherence to treatment
Advanced practice: cognitive-behavioral therapy (CBT)
Acute Stress Disorder
Adjustment disorder
- Precipitated by stressful event
- Debilitating cognitive, emotional, and behavioral symptoms that negatively impact normal functioning
- Responses to stressful event may include combinations of depression, anxiety, and conduct disturbances
Trauma-Related Disorders in Adults
Occur after significant adverse experiences/traumas
Individuals respond to stress with severe interruption of consciousness
Unconscious defense mechanism
Protects individual against overwhelming anxiety through emotional separation
Dissociative amnesia
Depersonalization/derealization disorder
Dissociative identity disorder
Cognitive factors
Environmental factors
Cultural considerations
Epidemiology
Etiology
Biological factors
- Genetic
- Neurobiological
Dissociative Disorders
Inability to recall important personal information
Often of traumatic or stressful nature
Dissociative fugue
- Subtype characterized by sudden, unexpected travel and inability to recall one's identity
Dissociative Amnesia
Depersonalization—focus on self (im not real)
Derealization—focus on outside world (nothing is real)
Depersonalization/Derealization Disorder
Presence of two or more distinct personality states
Each alternate personality (alter) has own pattern of
- Perceiving
- Relating to and
- Thinking about the self and environment
Dissociative Identity Disorder aka multiple personality disorder
History
Moods
Impact on patient and family
Suicide risk
Self-assessment
Dissociative Disorders Assessment
Phase 1: Establishing safety, stabilization, and symptom reduction
Phase 2: Confronting, working through, and integrating traumatic memories
Phase 3: Identity integration and rehabilitation
Dissociative Disorders Planning
Interventions
- Psychoeducation
- Pharmacological interventions
Advanced practice interventions
- CBT, psychodynamic psychotherapy, exposure therapy, modified EMDR therapy, hypnotherapy, neurofeedback, ego state therapies, somatic therapies, and medication
Dissociative Disorders implementation
A nurse assesses a patient diagnosed with dissociative identity disorder. Which finding would likely be part of the patient's history?
A.Travel to a foreign country
B.Physical or sexual abuse
C.Thyroid dysfunction
D.Eating disorder
B.Physical or sexual abuse
Expression of stress through physical symptoms that are often manifestations of psychological and emotional distress
Symptoms expressed in place of anxiety, depression, or irritability
Holistic approach: multidimensional interplay of biological, psychological, and sociocultural needs and its effects on somatization
somatization
Somatic symptom disorder (SSD) (physical symptoms)
Illness anxiety disorder
Conversion disorder (convert mental illness to physical)
Psychological factors affecting medical condition
Factitious disorder (make yourself sick or injured for the attention)
clinical picture (somatic symptom disorder)
One or more distressing symptoms
Excessive thoughts, anxiety and behaviors around symptoms, or health concerns
Without significant physical findings and medical diagnosis
Suffering is authentic
High level of functional impairment
Somatic Symptom Disorder
Misinterpretation of physical sensations
Preoccupation with having or acquiring serious illness for at least 6 months
High anxiety about health
Excessive health-related behaviors or maladaptive avoidance
May be care-seeking or care-avoidant
Illness Anxiety Disorder
Neurological symptoms in the absence of a neurological diagnosis
Presence of deficits in voluntary motor or sensory functions
Common symptoms—paralysis, blindness, movement and gait disorders, numbness, paresthesias, loss of vision or hearing, or episodes resembling epilepsy
"La belle indifférence" versus distress
Conversion Disorder
Psychological factors that increase risk for medical diseases, magnify them, or interfere with their treatment
Depression
- Cardiovascular diseases and cancer
Stress
Psychological Factors Affecting Medical Condition
Mr. Brazzali is brought to the Emergency Department by a cab driver who walks with him into the entrance and says, "This guy says he just lost his sight! He just went blind after he got into my cab."
Mr. Brazzali is very patient and says, during assessment, "Well, I've had several episodes like this. I guess this just happens sometimes."
During assessment, Mr. Brazzali says that when these "episodes of blindness" come over him it is often immediately after "an epileptic fit." Testing, however, shows no signs of recent seizure.
The ED physician records that Mr. Brazzali has neurological symptoms but in the absence of a neurological diagnosis. He also makes note of this patient's lack of distress about what should be an alarming condition.
Which diagnosis best describes Mr. Brazzali's condition?
A.Psychological factors affecting medical condition
B.SSD
C.Illness anxiety disorder
D. Conversion disorder
D. Conversion disorder
Psychosocial factors
Coping skills
Spirituality and religion
Secondary gains
Cognitive style
Ability to communicate feelings and emotional needs
Dependence on medication
Self-assessment
assessment (somatic symptom disorder)
Ineffective coping
Anxiety
Risk for loneliness
Powerlessness, hopelessness
Social isolation
Pain
Altered family processes
Risk for suicide
Nursing Diagnoses (somatic symptom disorder)
Shared decision making
Patient participation
Outcome criteria realistic and attainable
Small steps or increments
- Patient can see concrete evidence of progress
Outcomes Identification (somatic symptom disorder)
Establish therapeutic relationship
Educate patient regarding treatment
Refer to support groups or systems
Teach effective coping
Focus on strengths and reinforce skills
Psychosocial interventions
- Coping strategies that preclude somatization
- Promotion of self-care activities
- Assertiveness training
Pharmacological interventions
Health teaching and promotion
Case management
implementation (somatic symptom disorder)
1. Provide continuity of care
2. Avoid unnecessary procedures
3. Provide frequent, brief, and regular visits
4. Always conduct a physical exam
5. Avoid disparaging comments
6. Set reasonable therapeutic goals
Six Key Elements for Effective Treatment (somatic symptom disorder)
Psychotherapy or consultation
Holistic approach
- Biological, environmental, psychological, spiritual, and sociocultural needs
Cognitive-behavioral therapy (CBT)
Act as nurse consultant or liaison
Advanced Practice Interventions (somatic symptom disorder)
Based on clear, realistic, measurable outcomes
Goals often reported as partially met
Patients
- Often report continuing somatic symptoms
- Often report less concern about them
evaluation (somatic symptom disorder)
Artificially, deliberately, and dramatically fabricate symptoms or self-inflict injury
Goal of assuming a sick role
Compulsivity
FAKE FAKE FAKE
Munchausen by proxy: done to the other person ex: gypsy rose
Factitious Disorder
Factitious disorder imposed on self (ATTENTION)
Factitious disorder imposed on another
Malingering (faking being sick for secondary gain)
- Condition related to factitious disorders
- Conscious fabrication of illness or exaggerating symptoms for secondary gain such as insurance fraud, prescription medication, avoidance of prison or military service
Types of Factitious Disorder
Assessment and diagnosis
- Determine if symptoms are conscious or unconscious
- Avoid confrontation
- Self-assessment: Frustrations related to countertransference
Planning and implementation
- Monitor for safety
- Prevent dangerous unnecessary treatments
Evaluation
- New coping strategies
Application of the Nursing Process (Factitious disorder)
Which problem does NOT fit the group?
A.Malingering
B.Conversion disorder
C.Illness anxiety disorder
D.SSD
A.Malingering
Which is an example of malingering?
A.Mr. Harris injures his foot to avoid military service.
B.Mrs. Adams has been making her child vomit and lose weight to pretend he has cancer.
C.Mr. Singleton has difficulty walking and uses a wheelchair, but without neurological deficits, which began 2 months after the death of his wife of 32 years.
D.Ms. Munini frequently calls or comes to the clinic in a panic, believing she is ill. Her suffering is genuine, but she never has concrete signs of any illness.
A.Mr. Harris injures his foot to avoid military service.
Which is an example of illness anxiety disorder?
A.Mr. Harris injures his foot to avoid military service.
B.Mrs. Adams has been making her child vomit and lose weight to pretend he has cancer.
C.Mr. Singleton has difficulty walking and uses a wheelchair, but without neurological deficits, which began two months after the death of his wife of 32 years.
D.Ms. Munini frequently calls or comes to the clinic in a panic, believing she is ill. Her suffering is genuine, but she never has concrete signs of any illness.
D.Ms. Munini frequently calls or comes to the clinic in a panic, believing she is ill. Her suffering is genuine, but she never has concrete signs of any illness.