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Longitudinal bone growth
Continuous remodeling of the epiphyseal plate on the diaphysis facing side in long bones. Ends when the chondrocytes of plate are replaced by bone.
Appositional bone growth
Increasing thickness or width. Addition to outside by osteoblasts in the osteogenic layer of the periosteum, destruction of the endosperm surface by osteoclasts
Infancy and childhood
Growth hormone from the anterior pituitary regulated by the thyroid- most important and ensures proper proportions of the skeleton
Puberty
Sex hormones promote a growth spurt and sex specific changes in the skeleton- ultimately leads to closure of the epiphyseal plate