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How long does the pancreas measure
12-15 cm long
what are the four areas of the pancreas
head, neck, body, and tail
what is the location of the pancreas
Non-encapsulated, Retroperitoneal Organ, Anterior pararenal space, Epigastric region, Lies Horizontal-oblique plane, Between C-loop of duodenum (2nd portion) and splenic hilum
what are the structures anterior to the pancreas
Stomach, portion of duodenum, transverse colon, GDA
what are the structures posterior to the pancreas
Common bile duct, Portal-splenic confluence (union of splenic vein and SMV), Aorta, IVC, Splenic vein, SMA & SMV (except for uncinate process)
where is the pancreas head located
Anterior to the inferior vena cava (IVC) and left renal vein, Most inferior portion of the gland, Inferior to the caudate lobe of the liver and the main portal vein
what does the pancreas head measure
2-3 cm AP
where does the common bile duct pass through the pancreas
passes through a groove posterior to the pancreatic head, and the GDA gastroduodenal artery passes through the anterior aspect of the head.
where is the uncinate process located
Medial, posterior extension of the head. It lies anterior to the IVC and posterior to SMV.
what is the uncinate process
Curved tip at the end of the pancreatic head.
where is the pancreas neck found
directly anterior to the portal-splenic confluence or superior mesenteric vein.
where is the portal vein formed
posterior to the neck by the junction of the superior mesenteric vein and splenic vein
what does the pancreas neck measure
1.5-2.5 cm AP
what is the largest and most anterior section
body of the pancreas
where does the body of the pancreas lie
anterior to the Aorta and Superior Mesenteric Artery
The tortuous splenic artery is usually the ___ of the pancreatic body
superior border
The splenic vein courses the ___ surface of the pancreas
posterior
what does the pancreas body measure
2-2.5 cm AP
where does the tail of the pancreas lie
Anterior to the left kidney, Posterior to left colic flexure & transverse colon
Splenic artery forms the ____ of the tail of pancreas
superior border
Splenic vein forms the ____ of the pancreas tail
posterior border
Stomach forms the ____ of the tail of the pancreas
anterior border
what does the tail of the pancreas measure
1-2 cm AP
what is the primary duct extending the entire length of the gland.
wirsung’s duct
what does the wirsung’s duct do
It receives tributaries from lobules at right angles and enters the duodenum with the common bile duct at major papilla--Ampulla of Vater (guarded by the sphincter of Oddi).
what is the sonographic appearance of wirsung’s duct
visualized coursing through the midline of the pancreas. It should measure < 2 mm
what is the accessory duct in the upper portion of the pancreatic head
santorini’s duct
what enters the duodenum at the minor papilla approximately 2 cm proximal to ampulla of Vater.
santorini’s duct
where is Blood supply to the head of the pancreas is supplied from
the GDA
The splenic artery and several smaller branches as well as the SMA supply blood to the
body and tail
what is venous drainage is through
tributaries of the splenic (SV) and superior mesenteric veins (SMV)
What are the superior border vascular and ductal landmarks
celiac axis (left gastric, common hepatic, splenic), GDA, and splenic artery
___ is a branch of the common hepatic artery and can be entering the anterior portion of the pancreatic head
GDA
Splenic artery is seen running along the ___ portion of the pancreas
superior
what is on the posterior border of the vascular and ductal landmarks
SMA, portal vein, and CBD
where can the SMA be seen
can be seen posterior to the pancreatic body
what is formed by the confluence SMV and splenic vein
portal vein
where is the CBD seen
Seen at the posterior portion of the pancreatic head
Where is the endocrine portion of the pancreas located
islets of langerhans
What is the primary function of the exocrine process
digestion
Acini cells are connected to what function
exocrine
Approxixmately how much pancreatic juice is produced per day
2L
What does sodium bicarbonate do in pancreatic juice
neutralize gastric acid
What enzyme breaks down fats
lipase
which enzyme breaks down proteins
trypsin
Which enzyme breaks down carbohydrates
amylase
which enzyme breaks down nucleic acids
nucleases
what are two main components of pancreatic juice mentioned on the slide
digestive enzymes and sodium bicarbonate
Is the endocrine portion of the pancreas ductal or non ductal
non ductal
where does the endocrine portion of the pancreas release hormones
directly into the bloodstream
which three types of cells are found in the islets of langerhans
alpha, beta, delta cells
which cells produce glucagon
alpha cells
what is the primary function of glucagon
converts glycogen to glucose to increase sugar levels
what cells produce insulin
beta
what is the primary effect of insulin in blood sugar
converts glucose to glycogen to decrease sugar levels
which cells inhibit the production of glucagon and insulin
delta
What happens when there is failure to produce adequate hormones
diabetes mellitus
what two main enzymes are affected with pancreatic disease
amylase and lipase
what does 2x normal level of amylase indicate
acute pancreatitis