Protein synthesis 2
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Last updated 2:39 PM on 4/28/23
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7 Terms
1
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Ribosome
* 2 subunits, one large and small
* E, P, and A site
* **E site**: releases tRNA molecules
* **P site**: holds onto one aa-tRNA and growing chain of amino acids
* **A site**: holds tRNA bringing the next amino acid
* A, P, E order
* arrival, projection, ejection
\
* E, P, and A site
* **E site**: releases tRNA molecules
* **P site**: holds onto one aa-tRNA and growing chain of amino acids
* **A site**: holds tRNA bringing the next amino acid
* A, P, E order
* arrival, projection, ejection
\
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Steps
1. Initiation
2. elongation
3. termination
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Initiation
1. start codon reaches the P site
2. tRNA attaches to the start codon
3. find the codon which tells us what amino acid attaches to the anticodon (tRNA)
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Start Codon
AUG
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mRNA
is the __codon__, tRNA is the __anticodon__.
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Elongation
1. A site gets an anticodon that attaches with the matching nucleotides
2. both amino acids attach to each other with a peptide bond
3. ribosome moves down, the tRNA gets to the E site, and gets ejected
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Termination
1. A site reaches a STOP codon
2. a release factor binds to the A site
3. release factor cuts the protein off from the mRNA
4. goes to the Golgi apparatus to be folded